IT8522214A0 - Esapeptidi ad attivita' ipotensiva. - Google Patents
Esapeptidi ad attivita' ipotensiva.Info
- Publication number
- IT8522214A0 IT8522214A0 IT8522214A IT2221485A IT8522214A0 IT 8522214 A0 IT8522214 A0 IT 8522214A0 IT 8522214 A IT8522214 A IT 8522214A IT 2221485 A IT2221485 A IT 2221485A IT 8522214 A0 IT8522214 A0 IT 8522214A0
- Authority
- IT
- Italy
- Prior art keywords
- hexapeptides
- hypotensive activity
- hypotensive
- activity
- Prior art date
Links
- 230000001077 hypotensive effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22214/85A IT1190389B (it) | 1985-09-19 | 1985-09-19 | Esapeptidi ad attivita' ipotensiva |
US06/893,146 US4732890A (en) | 1985-09-19 | 1986-08-05 | Retro-inverso hexapeptide neurotensin analogs, process for their preparation and pharmaceutical compositions containing them |
JP61208104A JPS6270396A (ja) | 1985-09-19 | 1986-09-05 | retro逆転ヘキサペプチドニユ−ロテンシン類似体 |
EP86112387A EP0215410A3 (en) | 1985-09-19 | 1986-09-08 | Retro-inverso hexapeptide neurotensin analogs, process for their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22214/85A IT1190389B (it) | 1985-09-19 | 1985-09-19 | Esapeptidi ad attivita' ipotensiva |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8522214A0 true IT8522214A0 (it) | 1985-09-19 |
IT1190389B IT1190389B (it) | 1988-02-16 |
Family
ID=11193147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22214/85A IT1190389B (it) | 1985-09-19 | 1985-09-19 | Esapeptidi ad attivita' ipotensiva |
Country Status (4)
Country | Link |
---|---|
US (1) | US4732890A (it) |
EP (1) | EP0215410A3 (it) |
JP (1) | JPS6270396A (it) |
IT (1) | IT1190389B (it) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5162497A (en) * | 1987-09-24 | 1992-11-10 | The Administrators Of The Tulane Educational Fund | Bradykinin analogs with non-peptide bond |
US5877277A (en) | 1987-09-24 | 1999-03-02 | Biomeasure, Inc. | Octapeptide bombesin analogs |
US5084555A (en) * | 1989-08-21 | 1992-01-28 | The Administrators Of The Tulane Educational Fund | An octapeptide bombesin analog |
IT1228451B (it) * | 1989-02-22 | 1991-06-19 | Sclavo S P A Siena | Nuovi derivati diamminici geminali e loro impiego nelle sintesi di peptidi retro-inversi |
US5767236A (en) * | 1990-05-09 | 1998-06-16 | Biomeasure, Inc. | Linear therapeutic peptides |
US5393740A (en) * | 1991-07-30 | 1995-02-28 | Tsumura & Co. | Neurotensin Hexapeptides |
US5374621A (en) * | 1991-09-13 | 1994-12-20 | Regents Of The University Of California | Neurotensin method for inhibiting vascular leakage |
US6458357B1 (en) | 1997-09-09 | 2002-10-01 | Myelos Corporation | Retro-inverso neurotrophic and analgesic peptides |
DK1400551T3 (da) * | 1998-08-28 | 2007-10-15 | Amylin Pharmaceuticals Inc | Polyamidkæder med præcis længde og deres konjugater med proteiner |
US6610820B1 (en) * | 1999-10-12 | 2003-08-26 | University Of Lausanne | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US6560542B1 (en) * | 2000-01-24 | 2003-05-06 | The Cielo Institute | Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins |
US6865492B2 (en) * | 2000-01-24 | 2005-03-08 | The Cielo Institute, Inc. | Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins |
US20050119454A1 (en) * | 2000-01-24 | 2005-06-02 | The Cielo Institute, Inc. | Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins |
WO2007031098A1 (en) | 2005-09-12 | 2007-03-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the jnk signal transduction pathway |
US8080517B2 (en) * | 2005-09-12 | 2011-12-20 | Xigen Sa | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
US20120058937A9 (en) * | 2008-04-15 | 2012-03-08 | Tsrl, Inc. | Prodrugs of Neuraminidase Inhibitors |
WO2009143864A1 (en) * | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases |
WO2009143865A1 (en) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
WO2010072228A1 (en) | 2008-12-22 | 2010-07-01 | Xigen S.A. | Novel transporter constructs and transporter cargo conjugate molecules |
JP5457813B2 (ja) * | 2009-12-16 | 2014-04-02 | ルネサスエレクトロニクス株式会社 | Adpll回路、半導体装置及び携帯情報機器 |
WO2011160653A1 (en) | 2010-06-21 | 2011-12-29 | Xigen S.A. | Novel jnk inhibitor molecules |
CA2807036C (en) | 2010-10-14 | 2018-01-16 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases |
WO2013091670A1 (en) | 2011-12-21 | 2013-06-27 | Xigen S.A. | Novel jnk inhibitor molecules for treatment of various diseases |
WO2014206427A1 (en) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
PL3013353T3 (pl) | 2013-06-26 | 2021-09-20 | Xigen Inflammation Ltd. | Przenikające do komórki inhibitory peptydowe szlaku przekazywania sygnału jnk do leczenia zapalenia pęcherza |
WO2015197097A1 (en) | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3929756A (en) * | 1973-11-21 | 1975-12-30 | Univ Brandeis | Synthetically produced tridecapeptide having the same activity as the hypothalamic substance, neurotensin |
IT1212508B (it) * | 1981-12-22 | 1989-11-22 | Anic Spa | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
IT1190891B (it) * | 1982-06-24 | 1988-02-24 | Anic Spa | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
IT1164225B (it) * | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
IT1164239B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica |
IT1164240B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica |
IT1206339B (it) * | 1984-01-13 | 1989-04-14 | Anic Spa | Analoghi retro-invertiti esapeptidici c-terminali della sostanza p. |
IT1178786B (it) * | 1984-12-21 | 1987-09-16 | Assorenti | Analoghi retro-inverso parzialmente modificati della neurotensina |
-
1985
- 1985-09-19 IT IT22214/85A patent/IT1190389B/it active
-
1986
- 1986-08-05 US US06/893,146 patent/US4732890A/en not_active Expired - Fee Related
- 1986-09-05 JP JP61208104A patent/JPS6270396A/ja active Pending
- 1986-09-08 EP EP86112387A patent/EP0215410A3/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0215410A2 (en) | 1987-03-25 |
US4732890A (en) | 1988-03-22 |
JPS6270396A (ja) | 1987-03-31 |
IT1190389B (it) | 1988-02-16 |
EP0215410A3 (en) | 1989-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT8522214A0 (it) | Esapeptidi ad attivita' ipotensiva. | |
IT8423173A0 (it) | Dipeptidi ad attivita'farmacologica. | |
FI861210A0 (fi) | N,n'-dialkylguanidinodipeptider. | |
IT8520973A0 (it) | Benzoil-uree ad attivita'insetticida. | |
NO862970L (no) | 3-propenylcephalosporinsolvater. | |
IT1187756B (it) | Isoindolinil-alchil-piperazine ad attivita' farmaceutica | |
IT8721063A0 (it) | Composizione ad attivita'tricogena. | |
IT1208512B (it) | Benzoil-uree ad attivita'insetticida. | |
NO863638D0 (no) | Oktapeptid. | |
FI854730A0 (fi) | Vattentorn 2000. | |
IT8521042A0 (it) | Composti tripeptidici ad azione ipotensiva. | |
IT8621194A0 (it) | Azolilderivati ad attivita'antifungina. | |
IT8620026A0 (it) | Tripeptide ad attivita'immunostimolante. | |
ATE74912T1 (de) | 2,2'-bi-1h-imidazole. | |
DK212786A (da) | 1,3-dioxanethere | |
IT8620027A0 (it) | Tripeptide ad attivita'immunostimolante. | |
IT8522424A0 (it) | Composto ad attivita'pilostimolante. | |
IT8419683A0 (it) | Composti ad attivita'ipolipemizzante. | |
IT8419682A0 (it) | Composti ad attivita'ipolipemizzante. | |
IT8522705A0 (it) | Azolilderivati ad attivita'antufungina. | |
IT8620495A1 (it) | 2,4-Dicloro-5-nitro-tiazolo | |
IT8419819A0 (it) | Azetidin-2-oni con attivita'antimicotica. | |
IT8821431A0 (it) | Composti ad attivita' fungicida. | |
IT8422702A0 (it) | Nuovi 2,3-diidro-1,4-benzodiossini 2,2-disostituiti ad attivita'ipotensiva. | |
IT207187Z2 (it) | Struttura di suola a flessibilita'differenziata. |