IT8023768A0 - Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina eprocedimento per la sua preparazione. - Google Patents

Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina eprocedimento per la sua preparazione.

Info

Publication number
IT8023768A0
IT8023768A0 IT8023768A IT2376880A IT8023768A0 IT 8023768 A0 IT8023768 A0 IT 8023768A0 IT 8023768 A IT8023768 A IT 8023768A IT 2376880 A IT2376880 A IT 2376880A IT 8023768 A0 IT8023768 A0 IT 8023768A0
Authority
IT
Italy
Prior art keywords
indazol
lysine
benzyl
salt
procedure
Prior art date
Application number
IT8023768A
Other languages
English (en)
Other versions
IT1131779B (it
Inventor
B Silvestrini
L Baiocchi
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of IT8023768A0 publication Critical patent/IT8023768A0/it
Priority to IT23768/80A priority Critical patent/IT1131779B/it
Priority to US06/269,923 priority patent/US4352813A/en
Priority to GB8118767A priority patent/GB2081708B/en
Priority to MX187939A priority patent/MX156471A/es
Priority to ES503509A priority patent/ES503509A0/es
Priority to PT73365A priority patent/PT73365B/pt
Priority to AR286096A priority patent/AR227677A1/es
Priority to FR8114549A priority patent/FR2489318B1/fr
Priority to JP56119033A priority patent/JPS5753465A/ja
Priority to NL8200222A priority patent/NL8200222A/nl
Priority to CA000394976A priority patent/CA1166643A/en
Priority to CH457/82A priority patent/CH651556A5/fr
Priority to SE8200424A priority patent/SE455306B/sv
Priority to AU79870/82A priority patent/AU536243B2/en
Priority to BE0/207152A priority patent/BE891914A/fr
Priority to DE19823202561 priority patent/DE3202561A1/de
Priority to SE8302552A priority patent/SE8302552L/xx
Application granted granted Critical
Publication of IT1131779B publication Critical patent/IT1131779B/it
Priority to BG098555A priority patent/BG60797B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT23768/80A 1980-07-29 1980-07-29 Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione IT1131779B (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT23768/80A IT1131779B (it) 1980-07-29 1980-07-29 Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione
US06/269,923 US4352813A (en) 1980-07-29 1981-06-02 [(1-Benzyl-1H-indazol-3-yl)oxy] acetic acid salt with L. lysine
GB8118767A GB2081708B (en) 1980-07-29 1981-06-18 Novel derivatives of (1-benzyl-1h-indazol-3-yl) oxyacetic acid and pharmaceutical composition containing it
MX187939A MX156471A (es) 1980-07-29 1981-06-23 Procedimiento para preparar la sal del acido ((1-bencil-1h-indazol-3-il)-bxi)acetico con lisina
ES503509A ES503509A0 (es) 1980-07-29 1981-06-29 Un procedimiento para preparar la sal del acido (1-bencil- 1h-indazol-3-il)oxi acetico con lisina
PT73365A PT73365B (en) 1980-07-29 1981-07-14 Process for the preparation of a new<(1-benzyl-1h-inazol-3yl) oxy>acetic acid salt with lysine
AR286096A AR227677A1 (es) 1980-07-29 1981-07-15 Procedimiento para preparar una sal de acido((1-bencil-1h-indazol-3-il)oxi)acetico con lisina
FR8114549A FR2489318B1 (fr) 1980-07-29 1981-07-27 Sel d'acide((1-benzyl-1h-indazol-3-yl)oxy)acetique avec la lysine
JP56119033A JPS5753465A (en) 1980-07-29 1981-07-28 Ricin salt of bendazac
NL8200222A NL8200222A (nl) 1980-07-29 1982-01-21 (1-benzyl-1h-indazool-3-yl)oxyazijnzuurlysinezout, werkwijze voor het bereiden ervan, alsmede therapeutische samenstelling, die dit zout bevat.
CA000394976A CA1166643A (en) 1980-07-29 1982-01-26 Salt of ¬(1-benzyl-1h-indazol-3-yl)oxy| acetic acid (or bendazac) with the lysine
CH457/82A CH651556A5 (en) 1980-07-29 1982-01-26 Salt of (benzylindazolyl)oxyacetic acid, process for the preparation of this salt and pharmaceutical composition containing this salt
SE8200424A SE455306B (sv) 1980-07-29 1982-01-27 Lysinsalt av /(1-bensyl-1h-indazol-3-yl)oxi/-ettiksyra
AU79870/82A AU536243B2 (en) 1980-07-29 1982-01-27 ((benzyl-1h-indazol-3-yl)oxy)acetic acid salt with lysine
BE0/207152A BE891914A (fr) 1980-07-29 1982-01-27 Sels d'acide (1-benzyl-1h-indazol-3-yl)oxy acetique avec la lysine, leur preparation et leur utilisation
DE19823202561 DE3202561A1 (de) 1980-07-29 1982-01-27 Lysinsalze der ((1-benzyl-1h-indazol-3-yl)-oxy)-essigsaeure, verfahren zu deren herstellung und diese enthaltende arzneimittel
SE8302552A SE8302552L (sv) 1980-07-29 1983-05-04 ( (1-bensyl-1h-indazol-3-yl)oxi) ettiksyrasalt med lysin
BG098555A BG60797B2 (bg) 1980-07-29 1994-02-24 Сол на(1-бензил-1н-индазол-3-ил)оксиоцетна киселина с лизин и метод за получаването й

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23768/80A IT1131779B (it) 1980-07-29 1980-07-29 Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione

Publications (2)

Publication Number Publication Date
IT8023768A0 true IT8023768A0 (it) 1980-07-29
IT1131779B IT1131779B (it) 1986-06-25

Family

ID=11209809

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23768/80A IT1131779B (it) 1980-07-29 1980-07-29 Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione

Country Status (17)

Country Link
US (1) US4352813A (it)
JP (1) JPS5753465A (it)
AR (1) AR227677A1 (it)
AU (1) AU536243B2 (it)
BE (1) BE891914A (it)
BG (1) BG60797B2 (it)
CA (1) CA1166643A (it)
CH (1) CH651556A5 (it)
DE (1) DE3202561A1 (it)
ES (1) ES503509A0 (it)
FR (1) FR2489318B1 (it)
GB (1) GB2081708B (it)
IT (1) IT1131779B (it)
MX (1) MX156471A (it)
NL (1) NL8200222A (it)
PT (1) PT73365B (it)
SE (2) SE455306B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1189052B (it) * 1981-11-27 1988-01-28 Acraf Trattamento della cataratta
IT1194564B (it) * 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
IT1230441B (it) 1989-02-07 1991-10-23 Acraf Eteri della serie dell'indazolo
IT1229674B (it) * 1989-04-26 1991-09-06 Acraf Composizione farmaceutica per uso topico oftalmico contenente bendazac o 5-0h bendazac
US5272169A (en) * 1992-03-27 1993-12-21 The Dupont Merck Pharmaceutical Company (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories
US5217983A (en) * 1992-03-27 1993-06-08 Du Pont Merck Pharmaceutical Company (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories
IT1293794B1 (it) * 1997-07-28 1999-03-10 Acraf Farmaco attivo nel ridurre la produzione di proteina mcp-1
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
CN103641784B (zh) * 2013-12-03 2018-06-19 杭州民生药业有限公司 一种苄达赖氨酸合成工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28032A (en) * 1966-08-29 1971-08-25 Acraf Indazol-3-yl-oxyalkanoic acids and process for the preparation thereof
FR1530097A (fr) 1966-08-29 1968-06-21 Acraf Acides indazole-3-yl-oxyalcanoïques et procédé pour leur préparation
NL6717184A (it) * 1967-12-16 1969-06-18 Stamicarbon
FR2217003A1 (en) * 1973-02-14 1974-09-06 Inst Investigaciones Terapeuti Benzopyrilacetic acid deriv prepn - by reacting 1-(p-chlorobenzoyl-2-methyl)-5-methoxy-benzopyrilacetic acid with a base
DE2940373A1 (de) * 1979-10-05 1981-04-23 Troponwerke GmbH & Co KG, 5000 Köln Lysin-(1-(p-chlorbenzoyl)-5-methoxy-2-methyl-3-indol) -acetoxy-acetate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
BE891914A (fr) 1982-05-17
FR2489318A1 (fr) 1982-03-05
BG60797B2 (bg) 1996-03-29
AU536243B2 (en) 1984-05-03
ES8203850A1 (es) 1982-04-01
MX156471A (es) 1988-08-26
SE8302552L (sv) 1983-07-28
GB2081708A (en) 1982-02-24
PT73365A (en) 1981-08-01
DE3202561A1 (de) 1983-08-04
JPH0322384B2 (it) 1991-03-26
IT1131779B (it) 1986-06-25
PT73365B (en) 1982-09-23
JPS5753465A (en) 1982-03-30
CA1166643A (en) 1984-05-01
CH651556A5 (en) 1985-09-30
FR2489318B1 (fr) 1986-01-03
SE8200424L (sv) 1983-07-28
AU7987082A (en) 1983-08-04
SE8302552D0 (sv) 1983-05-04
SE455306B (sv) 1988-07-04
NL8200222A (nl) 1983-08-16
ES503509A0 (es) 1982-04-01
AR227677A1 (es) 1982-11-30
GB2081708B (en) 1984-06-20
US4352813A (en) 1982-10-05

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 33

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 33, 19920211; AZIENDE CHIMICHE RIUNITE ANGELINI F RANCESCO

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960628