FR2489318B1 - Sel d'acide((1-benzyl-1h-indazol-3-yl)oxy)acetique avec la lysine - Google Patents

Sel d'acide((1-benzyl-1h-indazol-3-yl)oxy)acetique avec la lysine

Info

Publication number
FR2489318B1
FR2489318B1 FR8114549A FR8114549A FR2489318B1 FR 2489318 B1 FR2489318 B1 FR 2489318B1 FR 8114549 A FR8114549 A FR 8114549A FR 8114549 A FR8114549 A FR 8114549A FR 2489318 B1 FR2489318 B1 FR 2489318B1
Authority
FR
France
Prior art keywords
indazol
oxy
lysine
benzyl
acetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8114549A
Other languages
English (en)
Other versions
FR2489318A1 (fr
Inventor
Bruno Silvestrini
Leandro Baiocchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Publication of FR2489318A1 publication Critical patent/FR2489318A1/fr
Application granted granted Critical
Publication of FR2489318B1 publication Critical patent/FR2489318B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8114549A 1980-07-29 1981-07-27 Sel d'acide((1-benzyl-1h-indazol-3-yl)oxy)acetique avec la lysine Expired FR2489318B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23768/80A IT1131779B (it) 1980-07-29 1980-07-29 Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione

Publications (2)

Publication Number Publication Date
FR2489318A1 FR2489318A1 (fr) 1982-03-05
FR2489318B1 true FR2489318B1 (fr) 1986-01-03

Family

ID=11209809

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8114549A Expired FR2489318B1 (fr) 1980-07-29 1981-07-27 Sel d'acide((1-benzyl-1h-indazol-3-yl)oxy)acetique avec la lysine

Country Status (17)

Country Link
US (1) US4352813A (fr)
JP (1) JPS5753465A (fr)
AR (1) AR227677A1 (fr)
AU (1) AU536243B2 (fr)
BE (1) BE891914A (fr)
BG (1) BG60797B2 (fr)
CA (1) CA1166643A (fr)
CH (1) CH651556A5 (fr)
DE (1) DE3202561A1 (fr)
ES (1) ES8203850A1 (fr)
FR (1) FR2489318B1 (fr)
GB (1) GB2081708B (fr)
IT (1) IT1131779B (fr)
MX (1) MX156471A (fr)
NL (1) NL8200222A (fr)
PT (1) PT73365B (fr)
SE (2) SE455306B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1189052B (it) * 1981-11-27 1988-01-28 Acraf Trattamento della cataratta
IT1194564B (it) * 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
IT1230441B (it) 1989-02-07 1991-10-23 Acraf Eteri della serie dell'indazolo
IT1229674B (it) * 1989-04-26 1991-09-06 Acraf Composizione farmaceutica per uso topico oftalmico contenente bendazac o 5-0h bendazac
US5272169A (en) * 1992-03-27 1993-12-21 The Dupont Merck Pharmaceutical Company (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories
US5217983A (en) * 1992-03-27 1993-06-08 Du Pont Merck Pharmaceutical Company (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories
IT1293794B1 (it) * 1997-07-28 1999-03-10 Acraf Farmaco attivo nel ridurre la produzione di proteina mcp-1
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
CN103641784B (zh) * 2013-12-03 2018-06-19 杭州民生药业有限公司 一种苄达赖氨酸合成工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28032A (en) * 1966-08-29 1971-08-25 Acraf Indazol-3-yl-oxyalkanoic acids and process for the preparation thereof
FR1530097A (fr) 1966-08-29 1968-06-21 Acraf Acides indazole-3-yl-oxyalcanoïques et procédé pour leur préparation
NL6717184A (fr) * 1967-12-16 1969-06-18 Stamicarbon
FR2217003A1 (en) * 1973-02-14 1974-09-06 Inst Investigaciones Terapeuti Benzopyrilacetic acid deriv prepn - by reacting 1-(p-chlorobenzoyl-2-methyl)-5-methoxy-benzopyrilacetic acid with a base
DE2940373A1 (de) * 1979-10-05 1981-04-23 Troponwerke GmbH & Co KG, 5000 Köln Lysin-(1-(p-chlorbenzoyl)-5-methoxy-2-methyl-3-indol) -acetoxy-acetate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
DE3202561A1 (de) 1983-08-04
CA1166643A (fr) 1984-05-01
PT73365A (en) 1981-08-01
IT8023768A0 (it) 1980-07-29
AR227677A1 (es) 1982-11-30
ES503509A0 (es) 1982-04-01
SE455306B (sv) 1988-07-04
BG60797B2 (bg) 1996-03-29
NL8200222A (nl) 1983-08-16
AU536243B2 (en) 1984-05-03
ES8203850A1 (es) 1982-04-01
CH651556A5 (en) 1985-09-30
MX156471A (es) 1988-08-26
SE8302552L (sv) 1983-07-28
FR2489318A1 (fr) 1982-03-05
GB2081708A (en) 1982-02-24
US4352813A (en) 1982-10-05
GB2081708B (en) 1984-06-20
SE8200424L (sv) 1983-07-28
AU7987082A (en) 1983-08-04
BE891914A (fr) 1982-05-17
SE8302552D0 (sv) 1983-05-04
JPH0322384B2 (fr) 1991-03-26
PT73365B (en) 1982-09-23
JPS5753465A (en) 1982-03-30
IT1131779B (it) 1986-06-25

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Legal Events

Date Code Title Description
ST Notification of lapse