IT7968840A0 - Bis imidazoli particolarmente utili come antinfiammatori - Google Patents
Bis imidazoli particolarmente utili come antinfiammatoriInfo
- Publication number
- IT7968840A0 IT7968840A0 IT7968840A IT6884079A IT7968840A0 IT 7968840 A0 IT7968840 A0 IT 7968840A0 IT 7968840 A IT7968840 A IT 7968840A IT 6884079 A IT6884079 A IT 6884079A IT 7968840 A0 IT7968840 A0 IT 7968840A0
- Authority
- IT
- Italy
- Prior art keywords
- inflammators
- bis
- particularly useful
- imidazoles
- imidazoles particularly
- Prior art date
Links
- 150000002460 imidazoles Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/944,672 US4188397A (en) | 1978-09-22 | 1978-09-22 | 2,2-Alkyldiylbis(thio)bis(imidazoles) |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7968840A0 true IT7968840A0 (it) | 1979-09-19 |
IT1119165B IT1119165B (it) | 1986-03-03 |
Family
ID=25481849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT68840/79A IT1119165B (it) | 1978-09-22 | 1979-09-19 | Bis imidazoli particolarmente utili come antinfiammatori |
Country Status (6)
Country | Link |
---|---|
US (1) | US4188397A (it) |
EP (1) | EP0010361B1 (it) |
JP (1) | JPS5545693A (it) |
DE (1) | DE2965287D1 (it) |
IE (1) | IE49461B1 (it) |
IT (1) | IT1119165B (it) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5837255A (ja) * | 1981-08-26 | 1983-03-04 | 住金鋼材工業株式会社 | 合成床板 |
DE3468622D1 (en) * | 1983-05-17 | 1988-02-18 | Sanofi Sa | Pharmaceutical compositions containing symmetrical disulfides |
US4728656A (en) * | 1985-12-12 | 1988-03-01 | Smithkline Beckman Corporation | 2,2-alkyldiylbis(thio)bis(imidazoles) useful for inhibition of the 5-lipoxygenase pathway |
US4847270A (en) * | 1985-12-12 | 1989-07-11 | Smithkline Beckman Corporation | Inhibition of the 5-lipoxygenase pathway utilizing certain 2,2'-alkyldiyl bis(thio)bis-imidazoles and derivatives |
JPH0680057B2 (ja) * | 1986-04-28 | 1994-10-12 | 保土谷化学工業株式会社 | トリフエニルイミダゾ−ル及びその二量体 |
US4778806A (en) * | 1986-08-19 | 1988-10-18 | Smithkline Beckman Corporation | Inhibition of interleukin-1 production by monocytes and/or macrophages |
NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
US5021440A (en) * | 1989-07-31 | 1991-06-04 | Merck & Co., Inc. | Imidazole compounds and their use as transglutaminase inhibitors |
IE904450A1 (en) * | 1989-12-11 | 1991-06-19 | Rhone Poulenc Sante | Imidazoles |
IT1265209B1 (it) * | 1993-11-22 | 1996-10-31 | Pierrel Spa | Difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro |
US5620999A (en) * | 1994-07-28 | 1997-04-15 | Weier; Richard M. | Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation |
US6426360B1 (en) | 1994-07-28 | 2002-07-30 | G D Searle & Co. | 4,5-substituted imidazolyl compounds for the treatment of inflammation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3070599A (en) * | 1962-12-25 | Method fos preparing secondary amino- | ||
DE960279C (de) * | 1954-09-29 | 1957-03-21 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung von Bis-[imidazyl-(2)]-disulfid und dessen Abkoemmlingen |
US3086018A (en) * | 1957-12-24 | 1963-04-16 | Goodyear Tire & Rubber | Manufacture of amino thiazole disulfides |
DE1797027C3 (de) * | 1968-08-06 | 1980-03-13 | Agfa-Gevaert Ag, 5090 Leverkusen | Lichtempfindliches photographisches Aufzeichnungsmaterial |
SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
DE2856909A1 (de) * | 1978-12-28 | 1980-07-17 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
-
1978
- 1978-09-22 US US05/944,672 patent/US4188397A/en not_active Expired - Lifetime
-
1979
- 1979-09-13 IE IE1744/79A patent/IE49461B1/en unknown
- 1979-09-19 IT IT68840/79A patent/IT1119165B/it active
- 1979-09-20 EP EP79301957A patent/EP0010361B1/en not_active Expired
- 1979-09-20 DE DE7979301957T patent/DE2965287D1/de not_active Expired
- 1979-09-21 JP JP12250679A patent/JPS5545693A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
IE49461B1 (en) | 1985-10-16 |
IE791744L (en) | 1980-03-22 |
EP0010361A1 (en) | 1980-04-30 |
JPS6350353B2 (it) | 1988-10-07 |
IT1119165B (it) | 1986-03-03 |
EP0010361B1 (en) | 1983-04-27 |
US4188397A (en) | 1980-02-12 |
JPS5545693A (en) | 1980-03-31 |
DE2965287D1 (en) | 1983-06-01 |
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