IT7968009A0 - Arabinofuranosil nucleosidi e nucleotidi e procedimento per la loro preparazione - Google Patents

Arabinofuranosil nucleosidi e nucleotidi e procedimento per la loro preparazione

Info

Publication number
IT7968009A0
IT7968009A0 IT7968009A IT6800979A IT7968009A0 IT 7968009 A0 IT7968009 A0 IT 7968009A0 IT 7968009 A IT7968009 A IT 7968009A IT 6800979 A IT6800979 A IT 6800979A IT 7968009 A0 IT7968009 A0 IT 7968009A0
Authority
IT
Italy
Prior art keywords
arabinofuranosil
nucleosides
nucleotides
procedure
preparation
Prior art date
Application number
IT7968009A
Other languages
English (en)
Other versions
IT1120956B (it
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of IT7968009A0 publication Critical patent/IT7968009A0/it
Application granted granted Critical
Publication of IT1120956B publication Critical patent/IT1120956B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT68009/79A 1978-05-12 1979-05-11 Arabinofuranosil nucleosidi e nucleotidi e procedimento per la loro preparazione IT1120956B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/905,529 US4230698A (en) 1978-05-12 1978-05-12 2-Substituted arabinofuranosyl nucleosides and nucleotides

Publications (2)

Publication Number Publication Date
IT7968009A0 true IT7968009A0 (it) 1979-05-11
IT1120956B IT1120956B (it) 1986-03-26

Family

ID=25420991

Family Applications (1)

Application Number Title Priority Date Filing Date
IT68009/79A IT1120956B (it) 1978-05-12 1979-05-11 Arabinofuranosil nucleosidi e nucleotidi e procedimento per la loro preparazione

Country Status (7)

Country Link
US (1) US4230698A (it)
EP (1) EP0016005B1 (it)
JP (1) JPS55500441A (it)
DE (1) DE2967128D1 (it)
ES (1) ES480436A1 (it)
IT (1) IT1120956B (it)
WO (1) WO1979001068A1 (it)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5639019A (en) * 1979-09-05 1981-04-14 Yamasa Shoyu Co Ltd Antiviral agent
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
JPS5896024A (ja) * 1981-10-16 1983-06-07 リチヤ−ド・エフ・ストツケル 白金毒解毒剤
JPS58225097A (ja) * 1982-06-23 1983-12-27 Yamasa Shoyu Co Ltd ヌクレオシド５′−アルキルもしくはアルケニルりん酸
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
WO1987004929A1 (en) * 1986-02-20 1987-08-27 Greer Sheldon B Composition for and method of treating aids and certain related diseases
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
US4916122A (en) * 1987-01-28 1990-04-10 University Of Georgia Research Foundation, Inc. 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition
US4681933A (en) * 1986-05-01 1987-07-21 University Of Georgia Research Foundation, Inc. 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents
US4841039A (en) * 1986-05-01 1989-06-20 Emory University 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents
US5455339A (en) * 1986-05-01 1995-10-03 University Of Georgia Research Foundation, Inc. Method for the preparation of 2',3'-dideoxy and 2',3'-dideoxydide-hydro nucleosides
US5159067A (en) * 1987-01-28 1992-10-27 University Of Georgia Research Foundation Inc. 5'-Diphosphohexose nucleoside pharmaceutical compositions
US5190926A (en) * 1987-01-28 1993-03-02 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxypyrimidines and related compounds as antiviral agents
US5384396A (en) * 1988-02-23 1995-01-24 The University Of Georgia Research Foundation, Inc. Process for the deoxygenation of nucleosides
US5077280A (en) * 1988-04-12 1991-12-31 Brown University Research Foundation Treatment of viral infections
US5109124A (en) * 1988-06-01 1992-04-28 Biogen, Inc. Nucleic acid probe linked to a label having a terminal cysteine
US5006646A (en) * 1989-02-22 1991-04-09 Yuki Gosei Kogyo Co., Ltd. Process for preparing 2'-deoxy-5-trifluoromethyl-beta-uridine
US5118672A (en) * 1989-07-10 1992-06-02 University Of Georgia Research Foundation 5'-diphosphohexose nucleoside pharmaceutical compositions
US5681941A (en) * 1990-01-11 1997-10-28 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
US5175267A (en) * 1990-03-02 1992-12-29 University Of Georgia Research Foundation, Inc. Stereoselective glycosylation of hetercyclic bases
US5141943A (en) * 1990-04-12 1992-08-25 Brown University Research Foundation 5-benzyl barbiturate derivatives
US5278167A (en) * 1992-05-13 1994-01-11 Brown University Research Foundation 6-pyridyl substituted pyrimidine derivatives
US6232463B1 (en) 1997-10-09 2001-05-15 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
AUPP823099A0 (en) * 1999-01-18 1999-02-11 Alchemia Pty Ltd Protecting groups for carbohydrate synthesis
US6505948B2 (en) 2001-03-28 2003-01-14 Fusion Uv Systems, Inc. Method of modifying the spectral distribution of high-intensity ultraviolet lamps
JP5504179B2 (ja) 2008-03-03 2014-05-28 トスク インコーポレーティッド 毒性を低減するためのメトトレキセートアジュバントおよびその使用法
EP2794627B1 (en) 2011-12-22 2018-09-26 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
IL299328A (en) * 2020-07-07 2023-02-01 Theraonco Methods for treating cancer using an adapted monosaccharide compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3116282A (en) * 1960-04-27 1963-12-31 Upjohn Co Pyrimidine nucleosides and process
US3208997A (en) 1962-11-15 1965-09-28 Sankyo Co Process for preparing purine and pyrimidine nucleosides
US3501456A (en) * 1967-08-08 1970-03-17 Merck & Co Inc Arabinofuranosyl nucleosides and intermediates
US3755295A (en) * 1969-10-24 1973-08-28 Syntex Corp 1-(2-amino-2-deoxy-{62 -d-ribofuranosyl) pyrimidines and derivatives thereof
US3809689A (en) * 1971-02-25 1974-05-07 Syntex Inc Synthetic polyoxin type nucleosides and methods of preparing
US3987030A (en) * 1974-10-21 1976-10-19 Kyowa Hakko Kogyo Kabushiki Kaisha (2'-amino-2'-deoxypentofuranosyl) guanine and process for producing same
DE2627076A1 (de) * 1976-06-16 1977-12-29 Max Planck Gesellschaft Mittel zur inhibierung des zellwachstums
JPS5919556B2 (ja) * 1977-03-31 1984-05-07 協和醗酵工業株式会社 新規ヌクレオシドおよびその製法
JPS5919556A (ja) * 1982-07-27 1984-02-01 林化成株式会社 粒度分布幅のせまい板状軽質鉱物微粉末の製造法

Also Published As

Publication number Publication date
DE2967128D1 (en) 1984-08-30
EP0016005A1 (en) 1980-10-01
EP0016005B1 (en) 1984-07-25
ES480436A1 (es) 1980-08-16
US4230698A (en) 1980-10-28
EP0016005A4 (en) 1980-05-21
JPS55500441A (it) 1980-07-24
WO1979001068A1 (en) 1979-12-13
IT1120956B (it) 1986-03-26

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