IT1264855B1 - Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici - Google Patents

Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici

Info

Publication number
IT1264855B1
IT1264855B1 IT93MI001324A ITMI931324A IT1264855B1 IT 1264855 B1 IT1264855 B1 IT 1264855B1 IT 93MI001324 A IT93MI001324 A IT 93MI001324A IT MI931324 A ITMI931324 A IT MI931324A IT 1264855 B1 IT1264855 B1 IT 1264855B1
Authority
IT
Italy
Prior art keywords
isobutylphenyl
propionic acid
basic amino
amino acids
pharmaceutical compositions
Prior art date
Application number
IT93MI001324A
Other languages
English (en)
Italian (it)
Inventor
Federico Stroppolo
Daniele Bonadeo
Gian Franco Fornasini
Annibale Gazzaniga
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of ITMI931324A0 publication Critical patent/ITMI931324A0/it
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to IT93MI001324A priority Critical patent/IT1264855B1/it
Priority to BE9400519A priority patent/BE1007193A5/fr
Priority to CH01672/94A priority patent/CH686866A5/it
Priority to GB9410987A priority patent/GB2279251A/en
Priority to FR9406817A priority patent/FR2706891B1/fr
Priority to US08/255,945 priority patent/US5510385A/en
Priority to CA002125644A priority patent/CA2125644C/en
Priority to DE4420858A priority patent/DE4420858A1/de
Priority to JP6136833A priority patent/JPH0710749A/ja
Priority to NL9401006A priority patent/NL9401006A/nl
Priority to ES09401336A priority patent/ES2099022B1/es
Priority to SE9402156A priority patent/SE9402156L/xx
Publication of ITMI931324A1 publication Critical patent/ITMI931324A1/it
Application granted granted Critical
Publication of IT1264855B1 publication Critical patent/IT1264855B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT93MI001324A 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici IT1264855B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT93MI001324A IT1264855B1 (it) 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici
BE9400519A BE1007193A5 (fr) 1993-06-21 1994-05-20 Compositions pharmaceutiques contenant les sels d'acide s(+)-2-(4-isobutylphenyl) propionique avec des aminoacides basiques.
CH01672/94A CH686866A5 (it) 1993-06-21 1994-05-30 Composizioni farmaceutiche contenenti sali dell'acido S(+)-2-(4-isobutilfenil)propionico con amminoacidi basici scelti tra L-arginina e L-lisina
GB9410987A GB2279251A (en) 1993-06-21 1994-05-31 High dose pharmaceutical compositions
FR9406817A FR2706891B1 (enExample) 1993-06-21 1994-06-03
US08/255,945 US5510385A (en) 1993-06-21 1994-06-07 Pharmaceutical compositions containing the salts of S(+)-2-(4-isobutylphenyl)propionic acid with basic aminoacids
CA002125644A CA2125644C (en) 1993-06-21 1994-06-10 Pharmaceutical compositions containing the salts of s(+)-2-(4-isobutylphenyl)propionic acid with basic aminoacids
DE4420858A DE4420858A1 (de) 1993-06-21 1994-06-15 Pharmazeutische Zusammensetzungen, die Salze von S(+)-2-(4-Isobutylphenyl)propionsäure mit basischen Aminosäuren enthalten
JP6136833A JPH0710749A (ja) 1993-06-21 1994-06-20 Ｓ（＋）−２−（４−イソブチルフェニル）プロピオン酸と塩基性アミノ酸との塩を含有する医薬組成物
NL9401006A NL9401006A (nl) 1993-06-21 1994-06-20 Farmaceutische samenstellingen die de zouten van S(+)-2-(4-isobutylfenyl) propionzuur met basische aminozuren bevatten.
ES09401336A ES2099022B1 (es) 1993-06-21 1994-06-20 Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos.
SE9402156A SE9402156L (sv) 1993-06-21 1994-06-20 Farmaceutiska kompositioner innehållande salterna av s(+)-2- (4-isobutylfenyl)-propionsyra med basiska aminosyror

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001324A IT1264855B1 (it) 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici

Publications (3)

Publication Number Publication Date
ITMI931324A0 ITMI931324A0 (it) 1993-06-18
ITMI931324A1 ITMI931324A1 (it) 1994-12-21
IT1264855B1 true IT1264855B1 (it) 1996-10-17

Family

ID=11366435

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001324A IT1264855B1 (it) 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici

Country Status (12)

Country Link
US (1) US5510385A (enExample)
JP (1) JPH0710749A (enExample)
BE (1) BE1007193A5 (enExample)
CA (1) CA2125644C (enExample)
CH (1) CH686866A5 (enExample)
DE (1) DE4420858A1 (enExample)
ES (1) ES2099022B1 (enExample)
FR (1) FR2706891B1 (enExample)
GB (1) GB2279251A (enExample)
IT (1) IT1264855B1 (enExample)
NL (1) NL9401006A (enExample)
SE (1) SE9402156L (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0740935A4 (en) * 1994-02-24 1999-06-16 Otsuka Pharma Co Ltd ANALGETIC ACTIVITY AMPLIFIER
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US6251426B1 (en) 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6344479B1 (en) 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
CN100408029C (zh) * 2001-09-28 2008-08-06 麦克内尔-Ppc股份有限公司 有镶嵌部分的组合剂型
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
JP2006514982A (ja) 2003-03-21 2006-05-18 マクニール−ピーピーシー・インコーポレイテッド 非ステロイド抗炎症薬投薬計画
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
CA2570649A1 (en) * 2004-06-07 2005-12-22 Strides Arcolab Limited Pharmaceutical composition containing a stable and clear solution of anti-inflammatory drug in soft gelatin capsule and process for producing the same
US20050281876A1 (en) * 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20080075767A1 (en) * 2006-06-30 2008-03-27 Jin Xiao P Ibuprofen-containing liquid filled hard capsules
WO2008064192A2 (en) 2006-11-21 2008-05-29 Mcneil-Ppc, Inc. Modified release analgesic suspensions
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
JP5345620B2 (ja) 2007-08-15 2013-11-20 マクニール−ピーピーシー・インコーポレーテツド 即時放出及び徐放型イブプロフェンの投与法
US8143314B1 (en) * 2007-09-13 2012-03-27 Robert Carl Stover Methods and formulations for treating ineffective or decreased esophageal motility
CN101390844B (zh) * 2007-09-23 2011-11-09 天津医科大学 精氨酸布洛芬片剂及其制备方法
CN101265178A (zh) * 2008-04-25 2008-09-17 北京阜康仁生物制药科技有限公司 一种右旋布洛芬的氨基酸盐及其药用组合物
WO2010065936A1 (en) * 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
WO2010125212A1 (es) * 2009-04-27 2010-11-04 Laboratorio De Aplicaciones Farmacodinamicas, S.A. Suspensión oral de lisinato de ibuprofeno
CN101978955A (zh) * 2010-11-05 2011-02-23 航天中心医院 右旋布洛芬氨基酸盐片剂及其制备方法
ES2519592T3 (es) * 2011-11-17 2014-11-07 Zambon S.P.A. Composiciones sólidas farmacéuticas que contienen sales de ibuprofeno
HK1203162A1 (en) 2012-02-07 2015-10-23 麦克内尔-Ppc股份有限公司 Rapidly disintegrating coated tablets
BR112015005968A2 (pt) 2012-09-18 2017-07-04 Mcneil Ppc Inc formas de dosagem orais de liberação prolongada compreendendo partículas derivadas do ácido propiônico com baixo ponto de fusão
AU2013318356A1 (en) 2012-09-18 2015-03-19 Mcneil-Ppc, Inc. Low melting propionic acid derivative particles for use in oral dosage forms
US10583089B2 (en) 2016-07-19 2020-03-10 Johnson & Johnson Consumer Inc. Tablets having discontinuous coated regions
WO2018017553A2 (en) 2016-07-19 2018-01-25 Johnson & Johnson Consumer Inc. Tablets having discontinuous coated regions
WO2018094316A1 (en) 2016-11-21 2018-05-24 Just Biotherapeutics, Inc. Aflibercept formulations and uses thereof
JP7183268B2 (ja) 2017-11-20 2022-12-05 ジャスト－エヴォテック バイオロジックス、インコーポレイテッド 等張化剤としてリジン塩を含有するアフリベルセプト製剤及びその使用
WO2019142063A1 (en) 2018-01-22 2019-07-25 Johnson & Johnson Consumer Inc. Perforated capsules
US20210378968A1 (en) 2020-05-28 2021-12-09 Johnson & Johnson Consumer Inc. Multi-cavity customizable dosage forms

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
DE69022678T2 (de) * 1989-10-17 1996-03-21 Merck & Co Inc S(+)-Ibuprofen-L-Aminosäure und S(+)-Ibuprofen-D-Aminosäure als Analgetika mit grösserem pharmakologischem Potential.
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
HUT59656A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components
DK0505180T3 (da) * 1991-03-22 1997-03-24 Merck & Co Inc Farmaceutisk præparat med højt indhold af ibuprofenlysinat
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations

Also Published As

Publication number Publication date
CA2125644C (en) 2007-06-05
DE4420858A1 (de) 1994-12-22
ITMI931324A1 (it) 1994-12-21
ES2099022B1 (es) 1998-01-16
FR2706891B1 (enExample) 1995-10-20
ITMI931324A0 (it) 1993-06-18
GB9410987D0 (en) 1994-07-20
CA2125644A1 (en) 1994-12-22
GB2279251A (en) 1995-01-04
NL9401006A (nl) 1995-01-16
SE9402156L (sv) 1994-12-22
CH686866A5 (it) 1996-07-31
ES2099022A1 (es) 1997-05-01
SE9402156D0 (sv) 1994-06-20
FR2706891A1 (enExample) 1994-12-30
US5510385A (en) 1996-04-23
JPH0710749A (ja) 1995-01-13
BE1007193A5 (fr) 1995-04-18

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970522