IT1254991B - Procedimento per la preparazione di glicerofosfolipidi - Google Patents
Procedimento per la preparazione di glicerofosfolipidiInfo
- Publication number
- IT1254991B IT1254991B ITMI921552A ITMI921552A IT1254991B IT 1254991 B IT1254991 B IT 1254991B IT MI921552 A ITMI921552 A IT MI921552A IT MI921552 A ITMI921552 A IT MI921552A IT 1254991 B IT1254991 B IT 1254991B
- Authority
- IT
- Italy
- Prior art keywords
- glycerophospholipids
- procedure
- preparation
- fractionation
- inexpensive
- Prior art date
Links
- 150000002327 glycerophospholipids Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 238000005947 deacylation reaction Methods 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Abstract
Viene descritto un nuovo procedimento, semplice, economico ed applicabile su larga scala, per l'ottenimento con resa elevata di glicerofosfolipidi deacilati a partire da miscele dei corrispondenti derivati acilati di origine naturale o sintetica, caratterizzato dal fatto che la reazione di deacilazione e il frazionamento sono effettuati in una singola operazione in un reattore contenente una resina a scambio ionico di natura basica.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI921552A IT1254991B (it) | 1992-06-24 | 1992-06-24 | Procedimento per la preparazione di glicerofosfolipidi |
CA002092005A CA2092005A1 (en) | 1992-06-24 | 1993-03-08 | A process for the preparation of glycerophospholipids |
US08/027,946 US5315023A (en) | 1992-06-24 | 1993-03-08 | Process for the preparation of glycerophospholipids |
KR1019930003839A KR100262281B1 (ko) | 1992-06-24 | 1993-03-13 | 글리세로포스포리피드의 제조방법 |
JP10499093A JP3483908B2 (ja) | 1992-06-24 | 1993-04-07 | グリセロりん脂質の製造方法 |
ES93105892T ES2118851T3 (es) | 1992-06-24 | 1993-04-08 | Un procedimiento para la preparacion de glicerofosfolipidos. |
EP93105892A EP0575717B1 (en) | 1992-06-24 | 1993-04-08 | A process for the preparation of glycerophospholipids |
DE69320262T DE69320262T2 (de) | 1992-06-24 | 1993-04-08 | Verfahren zur Herstellung von Glycerophospholipiden |
AT93105892T ATE169628T1 (de) | 1992-06-24 | 1993-04-08 | Verfahren zur herstellung von glycerophospholipiden |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI921552A IT1254991B (it) | 1992-06-24 | 1992-06-24 | Procedimento per la preparazione di glicerofosfolipidi |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI921552A0 ITMI921552A0 (it) | 1992-06-24 |
ITMI921552A1 ITMI921552A1 (it) | 1993-12-24 |
IT1254991B true IT1254991B (it) | 1995-10-11 |
Family
ID=11363572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI921552A IT1254991B (it) | 1992-06-24 | 1992-06-24 | Procedimento per la preparazione di glicerofosfolipidi |
Country Status (9)
Country | Link |
---|---|
US (1) | US5315023A (it) |
EP (1) | EP0575717B1 (it) |
JP (1) | JP3483908B2 (it) |
KR (1) | KR100262281B1 (it) |
AT (1) | ATE169628T1 (it) |
CA (1) | CA2092005A1 (it) |
DE (1) | DE69320262T2 (it) |
ES (1) | ES2118851T3 (it) |
IT (1) | IT1254991B (it) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH683671A5 (it) * | 1992-03-30 | 1994-04-29 | Golgi Sa | Uso topico di glicerofosfolipidi deacilati. |
IT1265647B1 (it) * | 1992-11-18 | 1996-11-22 | Farmin Srl | Composizione farmaceutiche topiche per le allergie respiratorie |
DE4402492A1 (de) * | 1994-01-28 | 1995-08-03 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern |
IT1274027B (it) * | 1994-03-03 | 1997-07-14 | Zambon Spa | Processo per la preparazione e purificazione di mezzi di contrasto iodurati |
US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
FR2818967A1 (fr) * | 2001-01-04 | 2002-07-05 | Evatex | Dispositif de recyclage des eaux chargees en saumure et en polluants organiques |
US6878532B1 (en) | 2003-04-28 | 2005-04-12 | Sioux Biochemical, Inc. | Method of producing phosphatidylserine |
JP5420848B2 (ja) * | 2008-02-28 | 2014-02-19 | 株式会社コーセー | 美白剤及び美白用皮膚外用剤 |
KR101616945B1 (ko) | 2014-02-10 | 2016-04-29 | 엔자이텍 주식회사 | 라세믹 또는 광학적으로 활성이 있는 α―글리세로포스포릴 콜린의 제조방법 |
KR101622376B1 (ko) * | 2014-06-10 | 2016-05-18 | 케미 에스.피.에이. | L-α-글리세로포스포릴콜린을 정제하기 위한 프로세스 |
KR20160037031A (ko) | 2014-09-26 | 2016-04-05 | 엔자이텍 주식회사 | 라세믹 또는 광학적으로 활성이 있는 D 또는 L-α-글리세로포스포릴콜린 고체의 제조방법 |
KR20160116463A (ko) | 2015-03-30 | 2016-10-10 | 주식회사 한서켐 | L-α-글리세릴 포스포릴 콜린의 III형 결정 및 그 제조방법 |
RU2685238C1 (ru) * | 2016-07-01 | 2019-04-17 | Общество с ограниченной ответственностью "ФАРМАЦЕЛЬ" | Способ получения кристаллического глицерофосфатидилхолина |
KR102202757B1 (ko) | 2018-08-31 | 2021-01-13 | 롯데첨단소재(주) | 열가소성 수지 조성물 및 이로부터 형성된 성형품 |
CN114106036A (zh) * | 2021-11-08 | 2022-03-01 | 云南开放大学(云南国防工业职业技术学院) | 一种L-α-甘油磷脂酰胆碱的分离提取方法 |
KR102531373B1 (ko) | 2022-02-21 | 2023-05-12 | 이광미 | 난황 레시틴으로부터 콜린 알포세레이트를 제조하는 방법 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1229238B (it) * | 1989-05-08 | 1991-07-26 | Istituto Chemioterapico | Procedimento per la preparazione di l-alfa-glicerilfosforilcolina e l alfa glicerilfosforiletanolammina. |
JPH0387191A (ja) * | 1989-08-30 | 1991-04-11 | Nisshin Oil Mills Ltd:The | ホスファチジルイノシトールの製造方法 |
IT1240614B (it) * | 1990-03-30 | 1993-12-17 | Istituto Chemioterapico Italiano Fine Chimicals | Procedimento per la separazione dei principali componenti di una miscela di fosfolipidi grezzi deacilati |
-
1992
- 1992-06-24 IT ITMI921552A patent/IT1254991B/it active IP Right Grant
-
1993
- 1993-03-08 US US08/027,946 patent/US5315023A/en not_active Expired - Lifetime
- 1993-03-08 CA CA002092005A patent/CA2092005A1/en not_active Abandoned
- 1993-03-13 KR KR1019930003839A patent/KR100262281B1/ko not_active IP Right Cessation
- 1993-04-07 JP JP10499093A patent/JP3483908B2/ja not_active Expired - Lifetime
- 1993-04-08 AT AT93105892T patent/ATE169628T1/de not_active IP Right Cessation
- 1993-04-08 DE DE69320262T patent/DE69320262T2/de not_active Expired - Lifetime
- 1993-04-08 ES ES93105892T patent/ES2118851T3/es not_active Expired - Lifetime
- 1993-04-08 EP EP93105892A patent/EP0575717B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE169628T1 (de) | 1998-08-15 |
JPH07291982A (ja) | 1995-11-07 |
US5315023A (en) | 1994-05-24 |
DE69320262T2 (de) | 1999-01-07 |
ES2118851T3 (es) | 1998-10-01 |
JP3483908B2 (ja) | 2004-01-06 |
KR940005645A (ko) | 1994-03-22 |
ITMI921552A0 (it) | 1992-06-24 |
DE69320262D1 (de) | 1998-09-17 |
KR100262281B1 (ko) | 2000-07-15 |
CA2092005A1 (en) | 1993-12-25 |
EP0575717A1 (en) | 1993-12-29 |
ITMI921552A1 (it) | 1993-12-24 |
EP0575717B1 (en) | 1998-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970626 |