IT1250645B - Derivati di idroisochinolina - Google Patents
Derivati di idroisochinolinaInfo
- Publication number
- IT1250645B IT1250645B ITMI911863A IT1250645B IT 1250645 B IT1250645 B IT 1250645B IT MI911863 A ITMI911863 A IT MI911863A IT 1250645 B IT1250645 B IT 1250645B
- Authority
- IT
- Italy
- Prior art keywords
- octa
- hydro
- pain
- useful
- treatment
- Prior art date
Links
- 101100244562 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) oprD gene Proteins 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 108700023159 delta Opioid Receptors Proteins 0.000 title 1
- 102000048124 delta Opioid Receptors Human genes 0.000 title 1
- 150000004800 hydroisoquinoline derivatives Chemical class 0.000 title 1
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical compound C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 abstract 2
- LRGZZEOWQURWFK-UHFFFAOYSA-N 1,2,3,4,4a,5,6,7-octahydroisoquinoline Chemical compound C1NCCC2CCCC=C21 LRGZZEOWQURWFK-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001863 IT1250645B (it) | 1991-07-05 | 1991-07-05 | Derivati di idroisochinolina |
| US08/175,371 US5441956A (en) | 1991-07-05 | 1992-07-01 | Hydroisoquinoline derivatives |
| KR1019940700018A KR100241662B1 (ko) | 1991-07-05 | 1992-07-01 | 히드로이소퀴놀린 유도체 |
| EP92913507A EP0596897B1 (en) | 1991-07-05 | 1992-07-01 | Hydroisoquinoline derivatives |
| PCT/EP1992/001483 WO1993001186A1 (en) | 1991-07-05 | 1992-07-01 | Hydroisoquinoline derivatives |
| DE69232484T DE69232484T2 (de) | 1991-07-05 | 1992-07-01 | Hydroisochinolinderivate |
| ES92913507T ES2173866T3 (es) | 1991-07-05 | 1992-07-01 | Derivados de hidroisoquinolina. |
| AT92913507T ATE214390T1 (de) | 1991-07-05 | 1992-07-01 | Hydroisochinolinderivate |
| JP50194493A JP3253077B2 (ja) | 1991-07-05 | 1992-07-01 | ヒドロイソキノリン誘導体 |
| CA002112744A CA2112744A1 (en) | 1991-07-05 | 1992-07-01 | Hydroisoquinoline derivatives |
| AU21948/92A AU662007B2 (en) | 1991-07-05 | 1992-07-01 | Hydroisoquinoline derivatives |
| ZA924959A ZA924959B (en) | 1991-07-05 | 1992-07-03 | Hydroisoquinoline derivatives |
| MX9203939A MX9203939A (es) | 1991-07-05 | 1992-07-03 | Derivados de hidroisoquinolina y composiciones farmaceuticas que los contienen. |
| NZ243436A NZ243436A (en) | 1991-07-05 | 1992-07-03 | 4a-phenyl-6,7-heterocyclyl fused isoquinoline derivatives; preparatory processes and pharmaceutical compositions |
| PT100658A PT100658A (pt) | 1991-07-05 | 1992-07-03 | Derivados de hidro-isoquinolina e processo para a sua preparacao |
| IE218792A IE922187A1 (en) | 1991-07-05 | 1992-07-03 | Hydroisoquinoline derivatives |
| TW081105338A TW211567B (xx) | 1991-07-05 | 1992-07-06 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001863 IT1250645B (it) | 1991-07-05 | 1991-07-05 | Derivati di idroisochinolina |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI911863A0 ITMI911863A0 (it) | 1991-07-05 |
| ITMI911863A1 ITMI911863A1 (it) | 1993-01-06 |
| IT1250645B true IT1250645B (it) | 1995-04-21 |
Family
ID=11360290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT001863 IT1250645B (it) | 1991-07-05 | 1991-07-05 | Derivati di idroisochinolina |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | IT1250645B (xx) |
| ZA (1) | ZA924959B (xx) |
-
1991
- 1991-07-05 IT IT001863 patent/IT1250645B/it active IP Right Grant
-
1992
- 1992-07-03 ZA ZA924959A patent/ZA924959B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA924959B (en) | 1993-03-31 |
| ITMI911863A0 (it) | 1991-07-05 |
| ITMI911863A1 (it) | 1993-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950731 |