IT1250360B - Apparecchiatura di liofilizzazione a flusso continuo. - Google Patents
Apparecchiatura di liofilizzazione a flusso continuo.Info
- Publication number
- IT1250360B IT1250360B ITTO910959A ITTO910959A IT1250360B IT 1250360 B IT1250360 B IT 1250360B IT TO910959 A ITTO910959 A IT TO910959A IT TO910959 A ITTO910959 A IT TO910959A IT 1250360 B IT1250360 B IT 1250360B
- Authority
- IT
- Italy
- Prior art keywords
- continuous flow
- freeze
- dried
- lyophilization equipment
- rotating surfaces
- Prior art date
Links
- 238000004108 freeze drying Methods 0.000 title abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000006199 nebulizer Substances 0.000 abstract 1
- 238000007790 scraping Methods 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000000859 sublimation Methods 0.000 abstract 1
- 230000008022 sublimation Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
- F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Drying Of Solid Materials (AREA)
- Freezing, Cooling And Drying Of Foods (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Apparecchiatura di liofilizzazione a flusso continuo costituita da un contenitore (10) nella cui camera interna (11) é alloggiato un cilindro girevole (22) raffreddato sul quale un nebulizzatore (30) spruzza del materiale da liofilizzare.Una lama raschiante (38), sfiorando il materiale congelato, lo rimuove facendolo cadere sui piani girevoli (46-48-50-52-54-56) forati riscaldati da elementi riscaldanti (68) interposti tra detti piani girevoli, onde ottenere una rapida sublimazione della sostanza da liofilizzare.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITTO910959A IT1250360B (it) | 1991-12-11 | 1991-12-11 | Apparecchiatura di liofilizzazione a flusso continuo. |
EP92203581A EP0546597B1 (en) | 1991-12-11 | 1992-11-20 | Continuous freeze drying apparatus |
AT92203581T ATE124532T1 (de) | 1991-12-11 | 1992-11-20 | Kontinuierliche gefriertrocknungsvorrichtung. |
DK92203581.1T DK0546597T3 (da) | 1991-12-11 | 1992-11-20 | Kontinuert frysetørreapparat |
ES92203581T ES2073859T3 (es) | 1991-12-11 | 1992-11-20 | Aparato de secado continuo por congelacion. |
DE69203220T DE69203220T2 (de) | 1991-12-11 | 1992-11-20 | Kontinuierliche Gefriertrocknungsvorrichtung. |
US07/982,075 US5269077A (en) | 1991-12-11 | 1992-11-24 | Continuous freeze drying apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITTO910959A IT1250360B (it) | 1991-12-11 | 1991-12-11 | Apparecchiatura di liofilizzazione a flusso continuo. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITTO910959A0 ITTO910959A0 (it) | 1991-12-11 |
ITTO910959A1 ITTO910959A1 (it) | 1993-06-11 |
IT1250360B true IT1250360B (it) | 1995-04-07 |
Family
ID=11409769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITTO910959A IT1250360B (it) | 1991-12-11 | 1991-12-11 | Apparecchiatura di liofilizzazione a flusso continuo. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5269077A (it) |
EP (1) | EP0546597B1 (it) |
AT (1) | ATE124532T1 (it) |
DE (1) | DE69203220T2 (it) |
DK (1) | DK0546597T3 (it) |
ES (1) | ES2073859T3 (it) |
IT (1) | IT1250360B (it) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2051092C (en) * | 1990-09-12 | 2002-07-23 | Stephen A. Livesey | Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions |
WO1996022496A1 (en) * | 1995-01-20 | 1996-07-25 | Freezedry Specialties, Inc. | Freeze dryer |
DE19808408C1 (de) * | 1998-02-27 | 1999-06-24 | Bernd Dreisbach | Vakuum-Trockenschrank |
JP2002071019A (ja) | 2000-08-31 | 2002-03-08 | Aisin Ai Co Ltd | 変速機に用いられるアクチュエータの制御装置 |
JP5183068B2 (ja) * | 2003-12-22 | 2013-04-17 | フィンレイ,ウォーレン,エイチ | 大気噴出凍結乾燥法による粉末形成 |
US6935049B2 (en) * | 2003-12-24 | 2005-08-30 | Edward K. Alstat | Method and apparatus for reclaiming effluent from a freeze-drying process, and uses for effluent |
CN100494841C (zh) * | 2006-02-20 | 2009-06-03 | 李志平 | 冻干机 |
US20070294908A1 (en) * | 2006-06-21 | 2007-12-27 | Paolo Debolini | System for washing driers with shelves |
CA2754988C (en) * | 2009-03-11 | 2017-11-07 | Borregaard Industries Limited, Norge | Method for drying microfibrillated cellulose |
CA2782908C (en) | 2009-12-11 | 2016-02-09 | Edward Weisselberg | Apparatus and method for continuous lyophilization |
CN114259457A (zh) * | 2022-01-12 | 2022-04-01 | 江西灏洋生物科技有限公司 | 一种含酵母发酵相关产物的护肤品及其制备方法 |
CN114847354A (zh) * | 2022-05-27 | 2022-08-05 | 汕头市旺龙香生物科技有限公司 | 一种保健咀嚼奶片及其制备方法 |
CN116086162B (zh) * | 2022-11-22 | 2024-07-02 | 珠海格力电器股份有限公司 | 用于制冰机的烘干装置、制冰机及其控制方法、存储介质 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2616604A (en) * | 1941-05-02 | 1952-11-04 | Theodore R Folsom | Method for freezing and drying liquids and semisolids |
US2528476A (en) * | 1942-03-20 | 1950-10-31 | Thomas Lipton Inc | Method and apparatus for dehydration |
CH313992A (fr) * | 1953-09-22 | 1956-05-31 | Mouton Robert | Procédé de lyophilisation continu et appareil pour la mise en oeuvre du procédé |
US3218731A (en) * | 1962-03-19 | 1965-11-23 | Little Inc A | Vacuum freeze dryer having integral freezing means |
GB1042081A (en) * | 1963-03-02 | 1966-09-07 | Leybold Hochvakuum Anlagen | Improvements relating to the freeze drying of materials |
DE1629062C3 (de) * | 1963-08-02 | 1973-10-04 | Grasso's Koninklijke Machinefabrieken N.V., Herzogenbusch (Niederlande) | Vakuumtrocknungskammer zum Gefrieren und anschliessenden Trocknen von Gütern |
US3293766A (en) * | 1965-04-19 | 1966-12-27 | Cryo Maid | Freeze dried product and method |
FR1449444A (fr) * | 1965-10-09 | 1966-08-12 | Atlas Soc As | Procédé de congélation-dessiccation, et appareil pour la mise en oeuvre du procédé |
CH471358A (fr) * | 1968-03-11 | 1969-04-15 | Secfroid S A | Procédé de préparation d'un produit sec à partir de sa solution et installation pour la mise en oeuvre de ce procédé |
US3620776A (en) * | 1968-06-28 | 1971-11-16 | Nestle Sa | Spray drying process |
DE1933585A1 (de) * | 1969-07-02 | 1971-01-21 | Armbruster Dipl Phys Werner | Verfahren zur kontinuierlichen Vakuumgefriertrocknung und Vorrichtung zur Durchfuehrung dieses Verfahrens |
US3740860A (en) * | 1972-07-31 | 1973-06-26 | Smitherm Industries | Freeze drying method and apparatus |
FR2383412A1 (fr) * | 1977-03-11 | 1978-10-06 | Usifroid | Congelateur rotatif pour lyophilisateur ou analogue |
DE2738058A1 (de) * | 1977-08-24 | 1979-03-01 | Peter J Dipl Ing Schelauske | Verfahren zur kuehlung oder trocknung von schuettgut und kuehl- oder trockenstrecke zur durchfuehrung des verfahrens |
US4590684A (en) * | 1984-11-20 | 1986-05-27 | Eden Research Laboratories, Inc. | Continuous freeze drying |
CA2051092C (en) * | 1990-09-12 | 2002-07-23 | Stephen A. Livesey | Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions |
-
1991
- 1991-12-11 IT ITTO910959A patent/IT1250360B/it active IP Right Grant
-
1992
- 1992-11-20 EP EP92203581A patent/EP0546597B1/en not_active Expired - Lifetime
- 1992-11-20 DE DE69203220T patent/DE69203220T2/de not_active Expired - Lifetime
- 1992-11-20 DK DK92203581.1T patent/DK0546597T3/da active
- 1992-11-20 AT AT92203581T patent/ATE124532T1/de not_active IP Right Cessation
- 1992-11-20 ES ES92203581T patent/ES2073859T3/es not_active Expired - Lifetime
- 1992-11-24 US US07/982,075 patent/US5269077A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0546597B1 (en) | 1995-06-28 |
ES2073859T3 (es) | 1995-08-16 |
ATE124532T1 (de) | 1995-07-15 |
EP0546597A1 (en) | 1993-06-16 |
US5269077A (en) | 1993-12-14 |
DE69203220T2 (de) | 1995-11-02 |
ITTO910959A0 (it) | 1991-12-11 |
ITTO910959A1 (it) | 1993-06-11 |
DE69203220D1 (de) | 1995-08-03 |
DK0546597T3 (da) | 1995-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971125 |