IT1248702B - Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceutiche - Google Patents
Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceuticheInfo
- Publication number
- IT1248702B IT1248702B IT02056290A IT2056290A IT1248702B IT 1248702 B IT1248702 B IT 1248702B IT 02056290 A IT02056290 A IT 02056290A IT 2056290 A IT2056290 A IT 2056290A IT 1248702 B IT1248702 B IT 1248702B
- Authority
- IT
- Italy
- Prior art keywords
- pct
- mucoregulator
- preparation
- pharmaceutical compositions
- antitussive agent
- Prior art date
Links
- 229940124584 antitussives Drugs 0.000 title abstract 2
- 239000003434 antitussive agent Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
- 210000003097 mucus Anatomy 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/80—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paper (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02056290A IT1248702B (it) | 1990-06-06 | 1990-06-06 | Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceutiche |
| EP91911446A EP0532644B1 (en) | 1990-06-06 | 1991-06-03 | Antitussive and mucus regulating agent, a process for the preparation thereof and pharmaceutical compositions containing it |
| ES91911446T ES2061252T3 (es) | 1990-06-06 | 1991-06-03 | Agente antitusivo y regulador de la mucosa, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen. |
| AT91911446T ATE113029T1 (de) | 1990-06-06 | 1991-06-03 | Hustenstillendes und schleimregulierendes mittel, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zusammensetzungen. |
| PCT/EP1991/001023 WO1991018865A1 (en) | 1990-06-06 | 1991-06-03 | Antitussive and mucus regulating agent, a process for the preparation thereof and pharmaceutical compositions containing it |
| DE69104723T DE69104723T2 (de) | 1990-06-06 | 1991-06-03 | Hustenstillendes und schleimregulierendes mittel, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zusammensetzungen. |
| JP91510028A JPH05506450A (ja) | 1990-06-06 | 1991-06-03 | 鎮咳および粘液正常化活性を有する物質、その製造方法およびこれを含有する薬剤組成物 |
| AU79564/91A AU644452B2 (en) | 1990-06-06 | 1991-06-03 | Antitussive and mucus regulating agent, a process for the preparation thereof and pharmaceutical compositions containing it |
| US07/952,838 US5352703A (en) | 1990-06-06 | 1991-06-03 | Antitussive and mucus regulating agent, a process for the preparation thereof and pharmaceutical compositions containing it |
| CA002083597A CA2083597A1 (en) | 1990-06-06 | 1991-06-03 | Antitussive and mucus regulating agent, a process for the preparation thereof and pharmaceutical compositions containing it |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02056290A IT1248702B (it) | 1990-06-06 | 1990-06-06 | Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceutiche |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT9020562A0 IT9020562A0 (enExample) | 1990-06-06 |
| IT9020562A1 IT9020562A1 (it) | 1991-12-06 |
| IT1248702B true IT1248702B (it) | 1995-01-26 |
Family
ID=11168835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT02056290A IT1248702B (it) | 1990-06-06 | 1990-06-06 | Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceutiche |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5352703A (enExample) |
| EP (1) | EP0532644B1 (enExample) |
| JP (1) | JPH05506450A (enExample) |
| AT (1) | ATE113029T1 (enExample) |
| CA (1) | CA2083597A1 (enExample) |
| DE (1) | DE69104723T2 (enExample) |
| ES (1) | ES2061252T3 (enExample) |
| IT (1) | IT1248702B (enExample) |
| WO (1) | WO1991018865A1 (enExample) |
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|---|---|---|---|---|
| US20030166732A1 (en) * | 2002-02-27 | 2003-09-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity |
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| US9242939B2 (en) | 2012-05-10 | 2016-01-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of respiratory disorders |
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| WO2013167999A2 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of neurologic diseases |
| WO2013168014A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of familial amyloid polyneuropathy |
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| US9434729B2 (en) | 2012-05-23 | 2016-09-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of periodontitis and rheumatoid arthritis |
| WO2013175347A2 (en) * | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of respiratory disorders |
| JP2015518854A (ja) | 2012-05-23 | 2015-07-06 | セリックスビオ プライヴェート リミテッド | 多発性硬化症の治療のための組成物および方法 |
| SG11201407326XA (en) | 2012-05-23 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for treatment of mucositis |
| WO2013175376A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of local pain |
| NZ701832A (en) | 2012-05-23 | 2016-08-26 | Cellix Bio Private Ltd | Compositions and methods for treatment of inflammatory bowel disease |
| US9108942B1 (en) | 2014-11-05 | 2015-08-18 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
| US9187427B2 (en) | 2012-08-03 | 2015-11-17 | Cellix Bio Private Limited | N-substituted nicotinamide compounds and compositions for the treatment migraine and neurologic diseases |
| WO2014037833A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment inflammation and lipid disorders |
| AU2013311349A1 (en) | 2012-09-08 | 2014-11-27 | Cellixbio Private Limited | Compositions and methods for treatment of inflammation and lipid disorders |
| US9333187B1 (en) | 2013-05-15 | 2016-05-10 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
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| US9096537B1 (en) | 2014-12-31 | 2015-08-04 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
| SG11201706952VA (en) | 2014-09-26 | 2017-10-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of epilepsy and neurological disorders |
| EP3201168B1 (en) | 2014-09-29 | 2020-03-18 | Cellix Bio Private Limited | Compounds and compositions for the treatment of multiple sclerosis |
| AU2014414316B2 (en) | 2014-10-27 | 2020-04-09 | Cellix Bio Private Limited | Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis |
| US9321716B1 (en) | 2014-11-05 | 2016-04-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic syndrome |
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| US9173877B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of local pain |
| US9175008B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Prodrugs of anti-platelet agents |
| US9284287B1 (en) | 2014-11-05 | 2016-03-15 | Cellix Bio Private Limited | Compositions and methods for the suppression of carbonic anhydrase activity |
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| US9290486B1 (en) | 2014-11-05 | 2016-03-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy |
| WO2016088132A1 (en) | 2014-12-01 | 2016-06-09 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
| US9206111B1 (en) | 2014-12-17 | 2015-12-08 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
| JP6679616B2 (ja) | 2015-01-06 | 2020-04-22 | セリックス バイオ プライヴェート リミテッドCellix Bio Private Limited | 炎症及び疼痛の治療のための組成物及び方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1432904A (en) * | 1973-08-24 | 1976-04-22 | Uriach & Cia Sa J | N-2-n-cyclohexyl-n-methylaminomethyl-4,6-dibromo-phenyl-benzamides methods for their preparation and compositions containing them |
| FR2399276A1 (fr) * | 1977-08-03 | 1979-03-02 | Rhone Poulenc Ind | Procede de fabrication de billes d'alumine |
| CA1117546A (en) * | 1978-03-02 | 1982-02-02 | John D. Spivack | Hydrolytically stable ortho-alkylated phenyl phosphonites and stabilized compositions |
| IT1094864B (it) * | 1978-05-29 | 1985-08-10 | Tosi Franco Ist | Derivati della bromexina e procedimento per la loro preparazione |
| DK110582A (da) * | 1981-03-19 | 1982-09-20 | Hokuriku Pharmaceutical | 2-benzoylamino-substituerede benzylaminderivater samt fremgangsmaade til fremstilling af samme |
| IT1213132B (it) * | 1984-02-02 | 1989-12-14 | Yason Srl | Agente antibroncopneumopatico. |
-
1990
- 1990-06-06 IT IT02056290A patent/IT1248702B/it active IP Right Grant
-
1991
- 1991-06-03 JP JP91510028A patent/JPH05506450A/ja active Pending
- 1991-06-03 AT AT91911446T patent/ATE113029T1/de not_active IP Right Cessation
- 1991-06-03 CA CA002083597A patent/CA2083597A1/en not_active Abandoned
- 1991-06-03 EP EP91911446A patent/EP0532644B1/en not_active Revoked
- 1991-06-03 ES ES91911446T patent/ES2061252T3/es not_active Expired - Lifetime
- 1991-06-03 DE DE69104723T patent/DE69104723T2/de not_active Revoked
- 1991-06-03 WO PCT/EP1991/001023 patent/WO1991018865A1/en not_active Ceased
- 1991-06-03 US US07/952,838 patent/US5352703A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT9020562A1 (it) | 1991-12-06 |
| CA2083597A1 (en) | 1991-12-07 |
| EP0532644A1 (en) | 1993-03-24 |
| US5352703A (en) | 1994-10-04 |
| JPH05506450A (ja) | 1993-09-22 |
| ES2061252T3 (es) | 1994-12-01 |
| DE69104723T2 (de) | 1995-02-23 |
| WO1991018865A1 (en) | 1991-12-12 |
| EP0532644B1 (en) | 1994-10-19 |
| DE69104723D1 (de) | 1994-11-24 |
| IT9020562A0 (enExample) | 1990-06-06 |
| ATE113029T1 (de) | 1994-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960627 |