IT1242010B - Microsfere iniettabili, biodegradabili, loro procedimento di preparazione e sospensioni iniettabili che le contengono. - Google Patents

Microsfere iniettabili, biodegradabili, loro procedimento di preparazione e sospensioni iniettabili che le contengono.

Info

Publication number
IT1242010B
IT1242010B IT48470A IT4847090A IT1242010B IT 1242010 B IT1242010 B IT 1242010B IT 48470 A IT48470 A IT 48470A IT 4847090 A IT4847090 A IT 4847090A IT 1242010 B IT1242010 B IT 1242010B
Authority
IT
Italy
Prior art keywords
injectable
preparation procedure
suspensions containing
biodegradable microspheres
injectable suspensions
Prior art date
Application number
IT48470A
Other languages
English (en)
Other versions
IT9048470A1 (it
IT9048470A0 (it
Inventor
Gerard Cohen
Jean-Luc Dubois
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IT9048470A0 publication Critical patent/IT9048470A0/it
Publication of IT9048470A1 publication Critical patent/IT9048470A1/it
Application granted granted Critical
Publication of IT1242010B publication Critical patent/IT1242010B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT48470A 1989-11-15 1990-11-13 Microsfere iniettabili, biodegradabili, loro procedimento di preparazione e sospensioni iniettabili che le contengono. IT1242010B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR898914976A FR2654337B1 (fr) 1989-11-15 1989-11-15 Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.

Publications (3)

Publication Number Publication Date
IT9048470A0 IT9048470A0 (it) 1990-11-13
IT9048470A1 IT9048470A1 (it) 1992-05-13
IT1242010B true IT1242010B (it) 1994-02-02

Family

ID=9387417

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48470A IT1242010B (it) 1989-11-15 1990-11-13 Microsfere iniettabili, biodegradabili, loro procedimento di preparazione e sospensioni iniettabili che le contengono.

Country Status (13)

Country Link
JP (1) JPH03294229A (it)
AT (1) AT400298B (it)
BE (1) BE1005511A4 (it)
CA (1) CA2029940A1 (it)
CH (1) CH681691A5 (it)
DE (1) DE4036425A1 (it)
DK (1) DK270990A (it)
FR (1) FR2654337B1 (it)
GB (1) GB2239798B (it)
IT (1) IT1242010B (it)
LU (1) LU87836A1 (it)
NL (1) NL9002492A (it)
SE (1) SE9003570L (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
ES2105525T3 (es) * 1993-06-24 1997-10-16 Lilly Co Eli 2-fenil-3-aroilbenzotiofenos antiestrogenicos como agentes hipoglicemicos.
US5910492A (en) * 1995-06-05 1999-06-08 Takeda Chemical Industries, Ltd. Osteogenic promoting pharmaceutical composition
EP2210585A1 (en) 2009-01-16 2010-07-28 Exelgyn SPRM pharmaceutical compositions methods of treatment using them

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4293539A (en) * 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2528434B1 (fr) * 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
US4530840A (en) * 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
FR2537980B1 (fr) * 1982-12-17 1986-12-19 Sandoz Sa Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation
ES8502612A1 (es) * 1983-06-15 1985-02-01 Schering Ag Procedimiento para la preparacion de 13a-alquilgonanos
GB8327256D0 (en) * 1983-10-12 1983-11-16 Ici Plc Steroid derivatives
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
DE3347126A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2566779B2 (fr) * 1984-06-29 1987-03-06 Roussel Uclaf Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments
CA1256638A (en) * 1984-07-06 1989-06-27 Motoaki Tanaka Polymer and its production
FR2573657B1 (fr) * 1984-11-29 1989-05-12 Roussel Uclaf Produit comprenant une substance antiprogestomimetique et une substance uterotonique
DE3533175A1 (de) * 1985-09-13 1987-03-19 Schering Ag Antigestagene zur verschiebung der endometrialen reifung
FR2596395B1 (fr) * 1986-03-26 1989-05-26 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
US4758435A (en) * 1986-08-11 1988-07-19 American Cyanamid Company Estradiol implant composition and method for preparation
DE3633244A1 (de) * 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
EP0310542B1 (de) * 1987-10-01 1994-06-08 Schering Aktiengesellschaft Antigestagen- und antiöstrogenwirksame Verbindungen zur Behandlung hormonabhängiger Tumoren
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
DE3744054A1 (de) * 1987-12-21 1989-06-29 Schering Ag Verwendung von antigestagenen zur herstellung von arzneimitteln
JP2785023B2 (ja) * 1987-12-30 1998-08-13 ルセル―ユクラフ １７α位置を置換された１７β―ＯＨ―１９―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物
JP2670680B2 (ja) * 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法

Also Published As

Publication number Publication date
CA2029940A1 (fr) 1991-05-16
FR2654337B1 (fr) 1994-08-05
DK270990D0 (da) 1990-11-13
NL9002492A (nl) 1991-06-03
LU87836A1 (fr) 1991-05-07
IT9048470A1 (it) 1992-05-13
ATA231390A (de) 1995-04-15
AT400298B (de) 1995-11-27
IT9048470A0 (it) 1990-11-13
SE9003570D0 (sv) 1990-11-09
CH681691A5 (it) 1993-05-14
GB9024862D0 (en) 1991-01-02
FR2654337A1 (fr) 1991-05-17
JPH03294229A (ja) 1991-12-25
GB2239798B (en) 1993-10-27
BE1005511A4 (fr) 1993-08-31
GB2239798A (en) 1991-07-17
SE9003570L (sv) 1991-05-16
DK270990A (da) 1991-05-16
DE4036425A1 (de) 1991-05-16

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961105