IT1237360B - Formulazioni oftalmiche comprendenti bromocriptina - Google Patents
Formulazioni oftalmiche comprendenti bromocriptinaInfo
- Publication number
- IT1237360B IT1237360B IT8548703A IT4870385A IT1237360B IT 1237360 B IT1237360 B IT 1237360B IT 8548703 A IT8548703 A IT 8548703A IT 4870385 A IT4870385 A IT 4870385A IT 1237360 B IT1237360 B IT 1237360B
- Authority
- IT
- Italy
- Prior art keywords
- bromocriptine
- lyophilised
- compsn
- salt
- occular
- Prior art date
Links
- OZVBMTJYIDMWIL-AYFBDAFISA-N bromocriptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=C(Br)NC3=C1 OZVBMTJYIDMWIL-AYFBDAFISA-N 0.000 title abstract 2
- 229960002802 bromocriptine Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848426922A GB8426922D0 (en) | 1984-10-24 | 1984-10-24 | Galenic formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8548703A0 IT8548703A0 (it) | 1985-10-23 |
| IT1237360B true IT1237360B (it) | 1993-05-31 |
Family
ID=10568697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8548703A IT1237360B (it) | 1984-10-24 | 1985-10-23 | Formulazioni oftalmiche comprendenti bromocriptina |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4654345A (it) |
| JP (1) | JPS61103825A (it) |
| AU (1) | AU4892885A (it) |
| BE (1) | BE903483A (it) |
| DE (1) | DE3536560A1 (it) |
| DK (1) | DK484785A (it) |
| FR (1) | FR2571962A1 (it) |
| GB (2) | GB8426922D0 (it) |
| GR (1) | GR852545B (it) |
| IL (1) | IL76781A0 (it) |
| IT (1) | IT1237360B (it) |
| NL (1) | NL8502805A (it) |
| PT (1) | PT81352B (it) |
| SE (1) | SE8504976L (it) |
| ZA (1) | ZA858184B (it) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2012532A6 (es) * | 1988-07-15 | 1990-04-01 | Cusi Lab | Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica. |
| CA2030174C (en) * | 1990-01-10 | 1996-12-24 | Anthony H. Cincotta | Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates |
| FR2661832A1 (fr) * | 1990-05-11 | 1991-11-15 | Corbiere Jerome | Procede de stabilisation d'un derive d'ergoline et les compositions pharmaceutiques ainsi obtenues. |
| US5262422A (en) * | 1991-05-02 | 1993-11-16 | Sandoz Ltd. | Octahydrobenzo[g]quinoline |
| FR2680106B1 (fr) * | 1991-08-09 | 1994-03-11 | Corbiere Gerome | Procede de realisation de formes pharmaceutiques stables d'un derive d'ergoline et les compositions pharmaceutiques ainsi obtenues. |
| FI971533L (fi) * | 1994-10-13 | 1997-04-11 | Wakamoto Pharma Co Ltd | Lyofilisoituja farmaseuttisia valmisteita, jotka kykenevät muodostamaan vesipitoisen lääkekoostumuksen, jolla on palautuvan, lämpökovettuvan geelittymisen ominaisuus |
| GB9600426D0 (en) * | 1996-01-10 | 1996-03-13 | Ed Geistlich Sohne A G | Compositions |
| US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US20070275955A1 (en) * | 1997-07-31 | 2007-11-29 | Ed. Geistlich Soehne Ag | Method of treating tumors |
| US20050124608A1 (en) * | 2001-04-03 | 2005-06-09 | Redmond H. P. | Treatment of cancers |
| US7345039B2 (en) | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US6821968B2 (en) | 2001-09-26 | 2004-11-23 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Stable taurolidine electrolyte solutions |
| DK3445362T3 (da) | 2016-04-20 | 2021-10-11 | Veroscience Llc | Sammensætning og fremgangsmåde til behandling af stofskiftesygdomme |
| PL3697418T3 (pl) | 2017-10-18 | 2025-02-03 | Veroscience Llc | Polepszone preparaty bromokryptyny |
| PL430675A1 (pl) * | 2019-07-23 | 2021-01-25 | Osęka Maciej | Bromokryptyna do zastosowania w leczeniu chorób oczu związanych z podwyższonym poziomem śródbłonkowego czynnika wzrostu naczyń (VEGF) oraz kompozycja farmaceutyczna zawierająca bromokryptynę |
| CA3149877A1 (en) | 2019-09-23 | 2021-04-01 | Anthony H. Cincotta | Method for inducing tumor regression |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5637967B2 (it) * | 1973-05-17 | 1981-09-03 | ||
| CH601321A5 (it) * | 1975-01-06 | 1978-07-14 | Sandoz Ag | |
| US4039662A (en) * | 1975-12-04 | 1977-08-02 | Alcon Laboratories, Inc. | Ophthalmic solution |
| DE2750090A1 (de) * | 1976-11-19 | 1978-06-01 | Sandoz Ag | Neue verabreichungsformen fuer organische verbindungen |
| YU216177A (en) * | 1977-09-09 | 1984-02-29 | Rudolf Rucman | Process for preparing 2-bromo ergosine |
| YU40533B (en) * | 1978-09-04 | 1986-02-28 | Lek Tovarna Farmacevtskih | Process for preparing 2-bromoergosinine |
| FI793888A7 (fi) * | 1978-12-21 | 1981-01-01 | Sandoz Ag | Galeenisia seoksia. |
| US4283393A (en) * | 1979-03-13 | 1981-08-11 | Merck & Co., Inc. | Topical application of interferon inducers |
| DE3020895A1 (de) * | 1979-06-12 | 1980-12-18 | Sandoz Ag | Ergopeptinderivate, verfahren zu deren herstellung sowie diese ergopeptinderivate enthaltende pharmazeutischen zusammensetzungen |
| CA1141663A (en) * | 1979-09-06 | 1983-02-22 | Yukihisa Ishii | Ophthalmic solution for intraocular pressure adjustment |
| GB2058746A (en) * | 1979-09-20 | 1981-04-15 | Erba Farmitalia | 6,7-Secoergolines |
| DE3033898A1 (de) * | 1980-09-09 | 1982-04-22 | Dr. Thilo & Co GmbH, 8021 Sauerlach | Arzneimittel zur lokalen behandlung des glaukoms |
| BE890369A (fr) * | 1980-09-18 | 1982-03-16 | Sandoz Sa | Nouveaux medicaments a base d'inhibiteurs de la secretion de la prolactine pour le traitement de l'arteriosclerose |
| US4486416A (en) * | 1981-03-02 | 1984-12-04 | Soll David B | Protection of human and animal cells subject to exposure to trauma |
-
1984
- 1984-10-24 GB GB848426922A patent/GB8426922D0/en active Pending
-
1985
- 1985-10-14 NL NL8502805A patent/NL8502805A/nl not_active Application Discontinuation
- 1985-10-14 DE DE19853536560 patent/DE3536560A1/de not_active Withdrawn
- 1985-10-18 FR FR8515628A patent/FR2571962A1/fr active Pending
- 1985-10-18 US US06/789,251 patent/US4654345A/en not_active Expired - Fee Related
- 1985-10-21 BE BE1/011361A patent/BE903483A/fr not_active IP Right Cessation
- 1985-10-21 GB GB08525947A patent/GB2165752A/en not_active Withdrawn
- 1985-10-22 IL IL76781A patent/IL76781A0/xx unknown
- 1985-10-22 AU AU48928/85A patent/AU4892885A/en not_active Abandoned
- 1985-10-22 SE SE8504976A patent/SE8504976L/xx not_active Application Discontinuation
- 1985-10-22 PT PT81352A patent/PT81352B/pt unknown
- 1985-10-22 GR GR852545A patent/GR852545B/el unknown
- 1985-10-22 DK DK484785A patent/DK484785A/da not_active Application Discontinuation
- 1985-10-23 JP JP60238578A patent/JPS61103825A/ja active Pending
- 1985-10-23 IT IT8548703A patent/IT1237360B/it active
- 1985-10-24 ZA ZA858184A patent/ZA858184B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB8426922D0 (en) | 1984-11-28 |
| PT81352A (en) | 1985-11-01 |
| US4654345A (en) | 1987-03-31 |
| DK484785D0 (da) | 1985-10-22 |
| SE8504976D0 (sv) | 1985-10-22 |
| GR852545B (it) | 1986-02-18 |
| BE903483A (fr) | 1986-04-21 |
| PT81352B (en) | 1987-08-05 |
| GB2165752A (en) | 1986-04-23 |
| DK484785A (da) | 1986-04-25 |
| IT8548703A0 (it) | 1985-10-23 |
| ZA858184B (en) | 1987-06-24 |
| JPS61103825A (ja) | 1986-05-22 |
| DE3536560A1 (de) | 1986-04-24 |
| NL8502805A (nl) | 1986-05-16 |
| IL76781A0 (en) | 1986-02-28 |
| SE8504976L (sv) | 1986-04-25 |
| GB8525947D0 (en) | 1985-11-27 |
| AU4892885A (en) | 1986-07-17 |
| FR2571962A1 (fr) | 1986-04-25 |
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