IT1213495B - Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina - Google Patents

Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina

Info

Publication number
IT1213495B
IT1213495B IT8621734A IT2173486A IT1213495B IT 1213495 B IT1213495 B IT 1213495B IT 8621734 A IT8621734 A IT 8621734A IT 2173486 A IT2173486 A IT 2173486A IT 1213495 B IT1213495 B IT 1213495B
Authority
IT
Italy
Prior art keywords
ipoxatin
pentyloxycarbonyl
arginine
alpha
preparation process
Prior art date
Application number
IT8621734A
Other languages
English (en)
Italian (it)
Other versions
IT8621734A0 (it
Inventor
Riccardo Stradi
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IT8621734A0 publication Critical patent/IT8621734A0/it
Priority to IT8621734A priority Critical patent/IT1213495B/it
Priority to AT87113168T priority patent/ATE55130T1/de
Priority to EP87113168A priority patent/EP0260588B1/en
Priority to DE8787113168T priority patent/DE3764051D1/de
Priority to ES87113168T priority patent/ES2017485B3/es
Priority to IL83863A priority patent/IL83863A0/xx
Priority to PH35793A priority patent/PH25318A/en
Priority to JP62228206A priority patent/JPS6388184A/ja
Priority to IN669/MAS/87A priority patent/IN165609B/en
Priority to AR87308744A priority patent/AR242576A1/es
Priority to KR1019870010239A priority patent/KR950008971B1/ko
Priority to ZA876961A priority patent/ZA876961B/xx
Priority to CA000547042A priority patent/CA1276148C/en
Priority to AU78471/87A priority patent/AU593136B2/en
Priority to DK489087A priority patent/DK168570B1/da
Application granted granted Critical
Publication of IT1213495B publication Critical patent/IT1213495B/it
Priority to GR90400651T priority patent/GR3000796T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT8621734A 1986-09-17 1986-09-17 Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina IT1213495B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT8621734A IT1213495B (it) 1986-09-17 1986-09-17 Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina
AT87113168T ATE55130T1 (de) 1986-09-17 1987-09-09 Verfahren zur herstellung von alpha-n((hypoxanthin-9-yl)-pentyloxycarbonyl>-arginin.
EP87113168A EP0260588B1 (en) 1986-09-17 1987-09-09 Process for the preparation of alpha-N-[(hypoxanthin-9-yl)-pentyloxycarbonyl]-arginine
DE8787113168T DE3764051D1 (de) 1986-09-17 1987-09-09 Verfahren zur herstellung von alpha-n-((hypoxanthin-9-yl)-pentyloxycarbonyl)-arginin.
ES87113168T ES2017485B3 (es) 1986-09-17 1987-09-09 Proceso para la preparacion de alfa-n-(hipoxantin-9il)pentiloxi-carbonil-arginina.
IL83863A IL83863A0 (en) 1986-09-17 1987-09-10 Process for the preparation of alpha-n-(hypoxanthin-9-yl)-pentyloxycarbonyl)-arginine
PH35793A PH25318A (en) 1986-09-17 1987-09-10 Process for the preparation of (-n-£hypoxanthin-9-yl0 pentyloxycarbonyl|-arginine
JP62228206A JPS6388184A (ja) 1986-09-17 1987-09-11 α―Ｎ―〔（ハイポキサンチン―９―イル）―ペンチルオキシカルボニル〕―アルギニンの製造方法
IN669/MAS/87A IN165609B (forum.php) 1986-09-17 1987-09-14
AR87308744A AR242576A1 (es) 1986-09-17 1987-09-16 Proceso para la preparacion de alfa-n-¡(hipoxantin-9-il)-pentiloxicarbonil¿-arginina.
KR1019870010239A KR950008971B1 (ko) 1986-09-17 1987-09-16 α-N-[(히포크산틴-9-일)펜틸옥시카르보닐]알기닌의 제조방법
ZA876961A ZA876961B (en) 1986-09-17 1987-09-16 Process for the preparation of alpha-n-((hypoxanthin-9-yl)-pentyloxy-carbonyl)-arginine
CA000547042A CA1276148C (en) 1986-09-17 1987-09-16 Process for the preparation of -n-¬(hypoxanthin-9-yl)-pentyloxycarbonyl|-arginine
AU78471/87A AU593136B2 (en) 1986-09-17 1987-09-16 Process for the preparation of alpha-N- ((hypoxanthin -9-yl)- pentyloxycarbonyl)- arginine
DK489087A DK168570B1 (da) 1986-09-17 1987-09-17 Fremgangsmåde til fremstilling af alfa-N-[(hypoxanthin-9-yl)-pentyloxycarbonyl]-arginin
GR90400651T GR3000796T3 (en) 1986-09-17 1990-09-14 Process for the preparation of alpha-n-û(hypoxanthin-9-yl)-pentyloxycarbonyl¨-arginine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8621734A IT1213495B (it) 1986-09-17 1986-09-17 Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina

Publications (2)

Publication Number Publication Date
IT8621734A0 IT8621734A0 (it) 1986-09-17
IT1213495B true IT1213495B (it) 1989-12-20

Family

ID=11186113

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8621734A IT1213495B (it) 1986-09-17 1986-09-17 Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina

Country Status (16)

Country Link
EP (1) EP0260588B1 (forum.php)
JP (1) JPS6388184A (forum.php)
KR (1) KR950008971B1 (forum.php)
AR (1) AR242576A1 (forum.php)
AT (1) ATE55130T1 (forum.php)
AU (1) AU593136B2 (forum.php)
CA (1) CA1276148C (forum.php)
DE (1) DE3764051D1 (forum.php)
DK (1) DK168570B1 (forum.php)
ES (1) ES2017485B3 (forum.php)
GR (1) GR3000796T3 (forum.php)
IL (1) IL83863A0 (forum.php)
IN (1) IN165609B (forum.php)
IT (1) IT1213495B (forum.php)
PH (1) PH25318A (forum.php)
ZA (1) ZA876961B (forum.php)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241452B (it) * 1990-06-28 1994-01-17 Sigma Tau Ind Farmaceuti Derivati oligopeptidici dell'ipoxantina dotati di attivita' immunomodulante e composizioni farmaceutiche che li contengono
IT1244501B (it) * 1991-03-22 1994-07-15 Sigma Tau Ind Farmaceuti Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
WO1999047128A1 (en) 1998-03-19 1999-09-23 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
CN103153288B (zh) 2010-07-09 2017-02-15 詹姆斯·特林卡·格林 用于包括瑞格列净的短半衰期药物的组合立即/延迟释放递送系统

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221910A (en) * 1978-09-15 1980-09-09 Newport Pharmaceuticals International, Inc. 9-(Hydroxy alkyl)purines
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives

Also Published As

Publication number Publication date
PH25318A (en) 1991-04-30
AR242576A1 (es) 1993-04-30
DK489087D0 (da) 1987-09-17
IN165609B (forum.php) 1989-11-25
IT8621734A0 (it) 1986-09-17
EP0260588A1 (en) 1988-03-23
DK489087A (da) 1988-03-18
DK168570B1 (da) 1994-04-25
KR880003944A (ko) 1988-06-01
IL83863A0 (en) 1988-02-29
ATE55130T1 (de) 1990-08-15
AU593136B2 (en) 1990-02-01
CA1276148C (en) 1990-11-13
ZA876961B (en) 1988-05-25
AU7847187A (en) 1988-03-24
ES2017485B3 (es) 1991-02-16
DE3764051D1 (de) 1990-09-06
KR950008971B1 (ko) 1995-08-10
EP0260588B1 (en) 1990-08-01
GR3000796T3 (en) 1991-10-10
JPS6388184A (ja) 1988-04-19

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950928