IT1202811B - Associazione di farmaci per il trattamento dell'ipertensione a base di un diuretico e della (d-3-mercapto-2-metil propanoil)-l-prolina o suoi derivati - Google Patents

Associazione di farmaci per il trattamento dell'ipertensione a base di un diuretico e della (d-3-mercapto-2-metil propanoil)-l-prolina o suoi derivati

Info

Publication number
IT1202811B
IT1202811B IT31266/78A IT3126678A IT1202811B IT 1202811 B IT1202811 B IT 1202811B IT 31266/78 A IT31266/78 A IT 31266/78A IT 3126678 A IT3126678 A IT 3126678A IT 1202811 B IT1202811 B IT 1202811B
Authority
IT
Italy
Prior art keywords
propanoil
prolin
diuretic
mercapto
drugs
Prior art date
Application number
IT31266/78A
Other languages
English (en)
Italian (it)
Other versions
IT7831266A0 (it
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25343256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1202811(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT7831266A0 publication Critical patent/IT7831266A0/it
Application granted granted Critical
Publication of IT1202811B publication Critical patent/IT1202811B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT31266/78A 1977-12-27 1978-12-22 Associazione di farmaci per il trattamento dell'ipertensione a base di un diuretico e della (d-3-mercapto-2-metil propanoil)-l-prolina o suoi derivati IT1202811B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86442877A 1977-12-27 1977-12-27

Publications (2)

Publication Number Publication Date
IT7831266A0 IT7831266A0 (it) 1978-12-22
IT1202811B true IT1202811B (it) 1989-02-09

Family

ID=25343256

Family Applications (1)

Application Number Title Priority Date Filing Date
IT31266/78A IT1202811B (it) 1977-12-27 1978-12-22 Associazione di farmaci per il trattamento dell'ipertensione a base di un diuretico e della (d-3-mercapto-2-metil propanoil)-l-prolina o suoi derivati

Country Status (30)

Country Link
JP (1) JPS54110333A (xx)
AR (1) AR230378A1 (xx)
AU (1) AU526239B2 (xx)
BE (1) BE873092A (xx)
CA (1) CA1120400A (xx)
CH (1) CH642542A5 (xx)
DE (1) DE2854316C3 (xx)
DK (1) DK578778A (xx)
EG (1) EG14178A (xx)
FI (1) FI783991A (xx)
FR (1) FR2413089A1 (xx)
GB (1) GB2010675B (xx)
GR (1) GR72951B (xx)
HK (1) HK45483A (xx)
HU (1) HU178747B (xx)
IE (1) IE48306B1 (xx)
IL (1) IL56281A (xx)
IT (1) IT1202811B (xx)
KE (1) KE3235A (xx)
LU (1) LU80709A1 (xx)
MY (2) MY8300240A (xx)
NL (2) NL192870C (xx)
NO (1) NO784357L (xx)
NZ (1) NZ189159A (xx)
PH (1) PH22111A (xx)
PL (1) PL212188A1 (xx)
PT (1) PT68983A (xx)
SE (1) SE445173B (xx)
SG (1) SG41482G (xx)
ZA (1) ZA786948B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829950B2 (ja) * 1978-10-05 1983-06-25 ウェルファイド株式会社 環状イミノカルボン酸誘導体およびその塩類
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4482725A (en) * 1980-04-03 1984-11-13 E. R. Squibb & Sons, Inc. S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4552889A (en) * 1983-06-09 1985-11-12 Eli Lilly And Company 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
DE3532036A1 (de) * 1985-09-09 1987-03-26 Hoechst Ag Pharmazeutische zubereitung zur behandlung des bluthochdrucks
DK9200258U4 (da) * 1992-03-11 1993-07-23 Merck & Co Inc Farmaceutisk præparat indeholdende enalapril til brug mod hypertension
WO1996024358A1 (en) * 1995-02-10 1996-08-15 G.D. Searle & Co. Use of low dose amount of spironolactone for treatment of cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
GR72951B (xx) 1984-01-17
HU178747B (en) 1982-06-28
ZA786948B (en) 1980-04-30
NO784357L (no) 1979-06-28
FR2413089B1 (xx) 1980-12-26
HK45483A (en) 1983-10-28
JPS54110333A (en) 1979-08-29
NL7812164A (nl) 1979-06-29
JPS647045B2 (xx) 1989-02-07
NZ189159A (en) 1984-12-14
FI783991A (fi) 1979-06-28
FR2413089A1 (fr) 1979-07-27
NL980017I1 (nl) 1998-07-01
NL192870B (nl) 1997-12-01
AU526239B2 (en) 1982-12-23
MY102991A (en) 1993-03-31
KE3235A (en) 1982-11-05
DE2854316A1 (de) 1979-07-05
LU80709A1 (de) 1979-04-13
PT68983A (en) 1979-01-01
BE873092A (fr) 1979-06-27
GB2010675A (en) 1979-07-04
GB2010675B (en) 1982-06-16
SG41482G (en) 1985-01-11
MY8300240A (en) 1983-12-31
IE782413L (en) 1979-06-27
CA1120400A (en) 1982-03-23
DE2854316C2 (xx) 1989-08-10
DK578778A (da) 1979-06-28
PH22111A (en) 1988-06-01
IL56281A (en) 1983-05-15
EG14178A (en) 1984-06-30
PL212188A1 (xx) 1980-02-11
IT7831266A0 (it) 1978-12-22
AU4204178A (en) 1979-07-05
IE48306B1 (en) 1984-12-12
SE7813277L (sv) 1979-06-28
IL56281A0 (en) 1979-03-12
DE2854316C3 (de) 1994-12-22
NL192870C (nl) 1998-04-02
CH642542A5 (de) 1984-04-30
AR230378A1 (es) 1984-04-30
SE445173B (sv) 1986-06-09

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 42

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 42, 19920303; E.R. SQUIBB & SONS, INC.

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961227