IT1199239B - Linfochina,anticorpo monoclonale specifico per tale linfochina,e procedimento per la loro produzione - Google Patents

Linfochina,anticorpo monoclonale specifico per tale linfochina,e procedimento per la loro produzione

Info

Publication number
IT1199239B
IT1199239B IT49292/84A IT4929284A IT1199239B IT 1199239 B IT1199239 B IT 1199239B IT 49292/84 A IT49292/84 A IT 49292/84A IT 4929284 A IT4929284 A IT 4929284A IT 1199239 B IT1199239 B IT 1199239B
Authority
IT
Italy
Prior art keywords
linfokina
procedure
production
monoclonal antibody
antibody specific
Prior art date
Application number
IT49292/84A
Other languages
English (en)
Other versions
IT8449292A1 (it
IT8449292A0 (it
Inventor
Masakazu Mitsuhashi
Masashi Kurimoto
Original Assignee
Hayashibara Biochem Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58233570A external-priority patent/JPS60126228A/ja
Priority claimed from JP58244598A external-priority patent/JPS60142926A/ja
Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab
Publication of IT8449292A0 publication Critical patent/IT8449292A0/it
Publication of IT8449292A1 publication Critical patent/IT8449292A1/it
Application granted granted Critical
Publication of IT1199239B publication Critical patent/IT1199239B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT49292/84A 1983-12-13 1984-12-12 Linfochina,anticorpo monoclonale specifico per tale linfochina,e procedimento per la loro produzione IT1199239B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58233570A JPS60126228A (ja) 1983-12-13 1983-12-13 新リンホカイン１とその製造方法および用途
JP58244598A JPS60142926A (ja) 1983-12-27 1983-12-27 モノクロ−ナル抗体とその製造方法

Publications (3)

Publication Number Publication Date
IT8449292A0 IT8449292A0 (it) 1984-12-12
IT8449292A1 IT8449292A1 (it) 1986-06-12
IT1199239B true IT1199239B (it) 1988-12-30

Family

ID=26531084

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49292/84A IT1199239B (it) 1983-12-13 1984-12-12 Linfochina,anticorpo monoclonale specifico per tale linfochina,e procedimento per la loro produzione

Country Status (6)

Country Link
US (1) US4758549A (it)
KR (1) KR930000188B1 (it)
CH (1) CH664969A5 (it)
FR (1) FR2556220B1 (it)
GB (1) GB2153364B (it)
IT (1) IT1199239B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683688A (en) 1984-05-31 1997-11-04 Genentech, Inc. Unglycosylated recombinant human lymphotoxin polypeptides and compositions
US5672347A (en) * 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
US6686455B1 (en) 1984-07-05 2004-02-03 Genentech, Inc. Tumor necrosis factor
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
JPH0631318B2 (ja) * 1985-09-18 1994-04-27 株式会社林原生物化学研究所 新リンホカインｉｉｉとその製法
US4996145A (en) * 1987-10-27 1991-02-26 Oncotech Incorporated Method for detecting immune-mediated cytotoxicity
DE69132629T2 (de) * 1990-06-27 2002-04-18 Biogen, Inc. Oberflächenkomplexbildung von lymphotoxin
US7030080B2 (en) * 1990-06-27 2006-04-18 Biogen, Inc. Lymphotoxin-β, lymphotoxin-β complexes, pharmaceutical preparations and therapeutic uses thereof
US5795964A (en) * 1990-06-27 1998-08-18 Biogen, Inc. Lymphotoxin-beta and lymphotoxin-beta complexes
WO1996007673A1 (en) * 1994-09-09 1996-03-14 Nycomed Dak A/S Monocyte chemotaxin inducible proteins
US5925351A (en) 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
CA2666934A1 (en) * 2006-10-20 2008-04-24 Biogen Idec Ma Inc. Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
FR2513124B1 (fr) * 1981-07-21 1989-11-17 Hayashibara Biochem Lab Production et applications du facteur de lyse des cellules-cibles
US4481137A (en) * 1982-02-26 1984-11-06 Mochida Pharmaceutical Co., Ltd. Glycoproteins and processes for their production
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same

Also Published As

Publication number Publication date
IT8449292A1 (it) 1986-06-12
FR2556220A1 (fr) 1985-06-14
GB2153364A (en) 1985-08-21
GB8431152D0 (en) 1985-01-16
FR2556220B1 (fr) 1988-05-20
US4758549A (en) 1988-07-19
CH664969A5 (fr) 1988-04-15
IT8449292A0 (it) 1984-12-12
KR850004271A (ko) 1985-07-11
GB2153364B (en) 1987-09-23
KR930000188B1 (ko) 1993-01-11

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19941229