IT1197759B - Derivati acidi idrossicarbossilici oligomeri,loro preparazione e loro impiego - Google Patents

Derivati acidi idrossicarbossilici oligomeri,loro preparazione e loro impiego

Info

Publication number
IT1197759B
IT1197759B IT49520/83A IT4952083A IT1197759B IT 1197759 B IT1197759 B IT 1197759B IT 49520/83 A IT49520/83 A IT 49520/83A IT 4952083 A IT4952083 A IT 4952083A IT 1197759 B IT1197759 B IT 1197759B
Authority
IT
Italy
Prior art keywords
hydroxicarboxylic
preparation
acid derivatives
derivatives oligomers
oligomers
Prior art date
Application number
IT49520/83A
Other languages
English (en)
Other versions
IT8349520A0 (it
Inventor
Joachim Franz
Walter Prikoszovich
Zdenek Brich
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH737382A external-priority patent/CH651475A5/de
Priority claimed from CH737282A external-priority patent/CH660488A5/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8349520A0 publication Critical patent/IT8349520A0/it
Application granted granted Critical
Publication of IT1197759B publication Critical patent/IT1197759B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
IT49520/83A 1982-12-17 1983-12-16 Derivati acidi idrossicarbossilici oligomeri,loro preparazione e loro impiego IT1197759B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH737382A CH651475A5 (en) 1982-12-17 1982-12-17 Pharmaceutical composition for delayed release of the active substance under physiological conditions
CH737282A CH660488A5 (en) 1982-12-17 1982-12-17 (Co)oligomeric hydroxycarboxylic acid derivatives, the preparation thereof, and the use thereof in pharmaceutical compositions

Publications (2)

Publication Number Publication Date
IT8349520A0 IT8349520A0 (it) 1983-12-16
IT1197759B true IT1197759B (it) 1988-12-06

Family

ID=25701206

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49520/83A IT1197759B (it) 1982-12-17 1983-12-16 Derivati acidi idrossicarbossilici oligomeri,loro preparazione e loro impiego

Country Status (7)

Country Link
US (1) US4801739A (it)
CY (2) CY1529A (it)
DE (1) DE3345314A1 (it)
FR (1) FR2537980B1 (it)
GB (4) GB2135320B (it)
HK (1) HK27290A (it)
IT (1) IT1197759B (it)

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Publication number Priority date Publication date Assignee Title
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
DE3720806C2 (de) * 1986-07-03 1997-08-21 Clariant Finance Bvi Ltd Verwendung eines Stabilisators in Peroxydbleichverfahren
FR2654337B1 (fr) * 1989-11-15 1994-08-05 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
US5629173A (en) * 1990-08-09 1997-05-13 Genentech, Inc. Methods of use of serine protease variants having peptide ligase activity
US5342557A (en) * 1990-11-27 1994-08-30 United States Surgical Corporation Process for preparing polymer particles
PT99989A (pt) * 1991-01-09 1994-05-31 Alza Corp Dispositivos biodegradaveis e composicoes para libertacao difusivel de agentes
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
DE4224401A1 (de) * 1992-07-21 1994-01-27 Pharmatech Gmbh Neue biologisch abbaubare Polymere für die Arzneistoffgalenik
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
US5565215A (en) * 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
US5594091A (en) * 1994-02-21 1997-01-14 Takeda Chemical Industries, Ltd. Matrix for sustained-release preparation
US6007845A (en) * 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5942241A (en) 1995-06-09 1999-08-24 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
JP3301311B2 (ja) * 1996-05-24 2002-07-15 株式会社神戸製鋼所 ２−ヒドロキシカルボン酸オリゴマーの連続製造方法
JPH11511763A (ja) 1996-06-24 1999-10-12 ユーロ―セルティーク，エス．エイ． 安全な局所麻酔の提供方法
US6046187A (en) * 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US6126919A (en) * 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US6326042B1 (en) 1997-05-29 2001-12-04 The Curators Of The University Of Missouri Antimicrobial use of heat-treated lactic and/or glycolic acid compositions for treatment of ground meats
US5900266A (en) * 1997-05-29 1999-05-04 The Curators Of The University Of Missouri Heat-treated lactic and/or glycolic acid compositions and methods of use
BR9815499A (pt) * 1997-07-02 2001-01-02 Euro Celtique Sa Anestesia prolongada nas juntas e nos espacos corporais.
JP5046447B2 (ja) * 2000-08-07 2012-10-10 和光純薬工業株式会社 乳酸重合体及びその製造方法
WO2002058670A1 (en) * 2001-01-25 2002-08-01 Euroceltique S.A. Local anesthetic, and method of use
TWI332407B (en) * 2001-06-29 2010-11-01 Takeda Chemical Industries Ltd Controlled release composition and method of producting the same
DK1660039T3 (en) * 2003-07-18 2017-01-16 Oakwood Laboratories L L C PREVENTION OF REDUCTION OF THE POLYMER MOLECULE WEIGHT, THE PREPARATION OF PURPOSES AND GELING IN POLYMER COMPOSITIONS
PL1787658T3 (pl) 2005-11-10 2012-08-31 Italfarmaco Spa Formulacje o przedłużonym uwalnianiu analogów somatostatyny będących inhibitorami hormonu wzrostu
ES2791698T3 (es) 2006-12-18 2020-11-05 Takeda Pharmaceuticals Co Composición de liberación sostenida y método para producir la misma

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2362511A (en) * 1939-11-21 1944-11-14 Du Pont Modified glycolide resins
DE936746C (de) * 1953-05-01 1955-12-22 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Lactylmilchsaeureamiden
US3141030A (en) * 1961-12-28 1964-07-14 Paniplus Company Acyl lactylic acid compositions and methods of preparation thereof
US3440241A (en) * 1966-05-31 1969-04-22 Syntex Corp Preparation of 6-keto-14alpha-hydroxy-delta**7-dehydro steroids
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4010196A (en) * 1975-06-25 1977-03-01 American Home Products Corporation Linear polyester salts
US4011312A (en) * 1975-06-25 1977-03-08 American Home Products Corporation Prolonged release drug form for the treatment of bovine mastitis
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions

Also Published As

Publication number Publication date
GB2166652A (en) 1986-05-14
IT8349520A0 (it) 1983-12-16
GB8527421D0 (en) 1985-12-11
CY1530A (en) 1990-11-16
US4801739A (en) 1989-01-31
FR2537980B1 (fr) 1986-12-19
GB8527419D0 (en) 1985-12-11
GB2165454B (en) 1987-03-11
GB2135320A (en) 1984-08-30
DE3345314A1 (de) 1984-07-05
GB2135320B (en) 1987-04-29
GB2165454A (en) 1986-04-16
GB8333289D0 (en) 1984-01-18
GB8527420D0 (en) 1985-12-11
CY1529A (en) 1990-11-16
HK27290A (en) 1990-04-20
FR2537980A1 (fr) 1984-06-22
GB2166652B (en) 1987-03-11
GB2165849A (en) 1986-04-23

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