IT1194178B - Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti - Google Patents

Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti

Info

Publication number
IT1194178B
IT1194178B IT20334/83A IT2033483A IT1194178B IT 1194178 B IT1194178 B IT 1194178B IT 20334/83 A IT20334/83 A IT 20334/83A IT 2033483 A IT2033483 A IT 2033483A IT 1194178 B IT1194178 B IT 1194178B
Authority
IT
Italy
Prior art keywords
clobetasolo
esters
preparation
compounds obtained
compounds
Prior art date
Application number
IT20334/83A
Other languages
English (en)
Italian (it)
Other versions
IT8320334A0 (it
Inventor
Peter Macdonald
Original Assignee
Ricerche Steroidi Sirs Spa Soc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ricerche Steroidi Sirs Spa Soc filed Critical Ricerche Steroidi Sirs Spa Soc
Publication of IT8320334A0 publication Critical patent/IT8320334A0/it
Priority to IT20334/83A priority Critical patent/IT1194178B/it
Priority to NO840065A priority patent/NO840065L/no
Priority to CH113/84A priority patent/CH661930A5/it
Priority to SE8400145A priority patent/SE8400145L/
Priority to CA000445603A priority patent/CA1220468A/en
Priority to FI840344A priority patent/FI840344A/fi
Priority to JP59015956A priority patent/JPS59205397A/ja
Priority to DK42884A priority patent/DK42884A/da
Priority to JP59015957A priority patent/JPS59205399A/ja
Priority to NL8400910A priority patent/NL8400910A/nl
Priority to YU00546/84A priority patent/YU54684A/xx
Application granted granted Critical
Publication of IT1194178B publication Critical patent/IT1194178B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT20334/83A 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti IT1194178B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT20334/83A IT1194178B (it) 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti
NO840065A NO840065L (no) 1983-03-29 1984-01-09 Fremgangsmaate ved fremstilling av 17-estere av clobetasol
CH113/84A CH661930A5 (en) 1983-03-29 1984-01-10 Process for the preparation of 17-esters of clobetasol
SE8400145A SE8400145L (sv) 1983-03-29 1984-01-12 Forfarande for framstellning av 17-estrar av klobetasol
CA000445603A CA1220468A (en) 1983-03-29 1984-01-19 Process for the production of 17-esters of clobetasol
FI840344A FI840344A (fi) 1983-03-29 1984-01-27 Foerfarande foer framstaellning av 17- estrar av clobetasol.
JP59015956A JPS59205397A (ja) 1983-03-29 1984-01-31 クロベタゾ−ルの１７−エステルの製法
DK42884A DK42884A (da) 1983-03-29 1984-01-31 Fremgangsmaade til fremstilling af 17-estere af clobetasol
JP59015957A JPS59205399A (ja) 1983-03-29 1984-01-31 ２１―クロロ―９β，１１β―エポキシ―１７―ヒドロキシ―１６β―メチルプレグナ―１，４―ジエン―３，２０―ジオンの１７―エステルおよびその製法
NL8400910A NL8400910A (nl) 1983-03-29 1984-03-22 17-esters van clobetasol en werkwijze voor het bereiden daarvan.
YU00546/84A YU54684A (en) 1983-03-29 1984-03-28 Process for making 17-esthers of clobetasol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20334/83A IT1194178B (it) 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti

Publications (2)

Publication Number Publication Date
IT8320334A0 IT8320334A0 (it) 1983-03-29
IT1194178B true IT1194178B (it) 1988-09-14

Family

ID=11165811

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20334/83A IT1194178B (it) 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti

Country Status (10)

Country Link
JP (2) JPS59205397A (no)
CA (1) CA1220468A (no)
CH (1) CH661930A5 (no)
DK (1) DK42884A (no)
FI (1) FI840344A (no)
IT (1) IT1194178B (no)
NL (1) NL8400910A (no)
NO (1) NO840065L (no)
SE (1) SE8400145L (no)
YU (1) YU54684A (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108727458A (zh) * 2018-05-10 2018-11-02 浙江仙居仙乐药业有限公司 一种17-丙酸酯的合成方法
CN111944002A (zh) * 2020-07-29 2020-11-17 河南利华制药有限公司 一种倍氯米松二丙酸酯中间体及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1253831A (en) * 1968-01-19 1971-11-17 Glaxo Lab Ltd 9alpha,21-DIHALOPREGNANE COMPOUNDS
JPS51125372A (en) * 1975-03-31 1976-11-01 Taisho Pharmaceut Co Ltd Aprocess for preparing pregnane steroid-17-ester-21-halides

Also Published As

Publication number Publication date
NO840065L (no) 1984-10-01
YU54684A (en) 1986-10-31
JPS59205399A (ja) 1984-11-20
CH661930A5 (en) 1987-08-31
JPS59205397A (ja) 1984-11-20
FI840344A (fi) 1984-09-30
SE8400145D0 (sv) 1984-01-12
DK42884A (da) 1984-09-30
FI840344A0 (fi) 1984-01-27
DK42884D0 (da) 1984-01-31
IT8320334A0 (it) 1983-03-29
JPS6228160B2 (no) 1987-06-18
CA1220468A (en) 1987-04-14
SE8400145L (sv) 1984-09-30
NL8400910A (nl) 1984-10-16

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