IT1156755B - Derivati amminoalchilbenzenici utili come farmaceutici in particolare per la cura di ulcere gastriche e di allergie della pelle e relativo procedimento di produzione - Google Patents

Derivati amminoalchilbenzenici utili come farmaceutici in particolare per la cura di ulcere gastriche e di allergie della pelle e relativo procedimento di produzione

Info

Publication number
IT1156755B
IT1156755B IT7849419A IT4941978A IT1156755B IT 1156755 B IT1156755 B IT 1156755B IT 7849419 A IT7849419 A IT 7849419A IT 4941978 A IT4941978 A IT 4941978A IT 1156755 B IT1156755 B IT 1156755B
Authority
IT
Italy
Prior art keywords
alkylbenzenic
pharmaceuticals
amino
treatment
production process
Prior art date
Application number
IT7849419A
Other languages
English (en)
Italian (it)
Other versions
IT7849419A0 (it
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB20660/77A external-priority patent/GB1604674A/en
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Publication of IT7849419A0 publication Critical patent/IT7849419A0/it
Application granted granted Critical
Publication of IT1156755B publication Critical patent/IT1156755B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/10Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/08Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/30Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to nitro or nitroso groups
    • C07C279/32N-nitroguanidines
    • C07C279/36Substituted N-nitroguanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/06Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/06Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/08Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
IT7849419A 1977-05-17 1978-05-17 Derivati amminoalchilbenzenici utili come farmaceutici in particolare per la cura di ulcere gastriche e di allergie della pelle e relativo procedimento di produzione IT1156755B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB20660/77A GB1604674A (en) 1977-05-17 1977-05-17 Aminoalkyl-benzene derivatives
GB4012977 1977-09-27
GB1744478 1978-05-03

Publications (2)

Publication Number Publication Date
IT7849419A0 IT7849419A0 (it) 1978-05-17
IT1156755B true IT1156755B (it) 1987-02-04

Family

ID=27257503

Family Applications (1)

Application Number Title Priority Date Filing Date
IT7849419A IT1156755B (it) 1977-05-17 1978-05-17 Derivati amminoalchilbenzenici utili come farmaceutici in particolare per la cura di ulcere gastriche e di allergie della pelle e relativo procedimento di produzione

Country Status (13)

Country Link
JP (1) JPS53149936A (sv)
AU (2) AU523496B2 (sv)
CH (2) CH643238A5 (sv)
DE (1) DE2821410A1 (sv)
DK (1) DK214878A (sv)
ES (1) ES469953A1 (sv)
FI (1) FI781490A (sv)
FR (2) FR2401135A1 (sv)
IE (1) IE46886B1 (sv)
IT (1) IT1156755B (sv)
NL (1) NL7805344A (sv)
NZ (1) NZ187235A (sv)
SE (1) SE443558B (sv)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
NO800583L (no) * 1979-03-02 1980-09-03 Glaxo Group Ltd Fremgangsmaate for fremstilling av farmakologisk aktive triazolderivater
JPS568352A (en) * 1979-07-03 1981-01-28 Shionogi & Co Ltd Aminoalkylvenzene derivative
JPS609750B2 (ja) * 1979-07-03 1985-03-12 帝国臓器製薬株式会社 新規なn−置換フエノキシプロピルアミド化合物
US4293557A (en) 1979-07-03 1981-10-06 Teikoku Hormone Mfg. Co., Ltd. Antiulcer phenoxypropylamine derivatives
DE3070073D1 (en) * 1979-10-22 1985-03-14 Glaxo Group Ltd 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them
US4238487A (en) * 1979-10-31 1980-12-09 Merck & Co., Inc. Aminoalkyl benzofuran derivatives
FR2477537A1 (fr) * 1980-03-07 1981-09-11 Francaise Sucrerie Nouvelles guanidines acylees, urees et urees substituees, leur procede de fabrication et leur application en tant que medicaments
US4490533A (en) * 1980-12-22 1984-12-25 Merck & Co., Inc. Aminoalkyl pyridine derivatives
EP0057981A3 (en) 1981-02-09 1982-08-25 Beecham Group Plc Aromatic compounds, processes for their preparation and their use
JPS57165348A (en) * 1981-04-06 1982-10-12 Teikoku Hormone Mfg Co Ltd Novel aminoalkylbenzene derivative
US4526973A (en) * 1981-05-18 1985-07-02 Bristol-Myers Company Chemical compounds
US4522943A (en) * 1981-05-18 1985-06-11 Bristol-Myers Company Chemical compounds
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
AU8635482A (en) * 1981-07-24 1983-01-27 Glaxo Group Limited Derivatives of amino 1,2,4-triazoles
US4411899A (en) * 1981-12-21 1983-10-25 Merck & Co., Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors
JPS5988458A (ja) * 1982-11-12 1984-05-22 Toyama Chem Co Ltd アミン誘導体およびその塩
JPH0639466B2 (ja) * 1987-08-03 1994-05-25 杏林製薬株式会社 ウレア誘導体
JPH01131172A (ja) * 1987-08-28 1989-05-24 Toyama Chem Co Ltd アミン誘導体およびその塩、それらの製造法、並びにそれらを含有する抗潰瘍剤
WO1993023360A1 (fr) * 1992-05-12 1993-11-25 Zeria Pharmaceutical Co., Ltd. Nouveaux sels d'ammonium quaternaires et utilisation de ces sels comme medicament
TWI328009B (en) 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors
US8076516B2 (en) * 2007-11-01 2011-12-13 Acucela, Inc. Amine derivative compounds for treating ophthalmic diseases and disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE636468A (sv) *
US2785201A (en) * 1953-12-24 1957-03-12 Personnes A Responsabilite Lim Compounds of bis quaternary ammonium derivatives of phenylethylamine
US3047628A (en) * 1957-02-19 1962-07-31 Hoffmann La Roche Benzylamine derivatives
GB993581A (en) * 1960-03-03 1965-05-26 Wellcome Found Phenoxyalkylguanidines and their synthesis and pharmaceutical preparations containing them
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1421792A (en) * 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
JPS5227757A (en) * 1975-08-26 1977-03-02 Kyowa Hakko Kogyo Co Ltd Preparation of 6-aminomethylnaphthalene derivatives

Also Published As

Publication number Publication date
JPS53149936A (en) 1978-12-27
FR2401135A1 (fr) 1979-03-23
AU541144B2 (en) 1984-12-20
FI781490A (fi) 1978-11-18
IE46886B1 (en) 1983-10-19
DK214878A (da) 1978-11-18
FR2401135B1 (sv) 1983-08-19
AU523496B2 (en) 1982-07-29
NZ187235A (en) 1981-10-19
SE443558B (sv) 1986-03-03
FR2398718B1 (sv) 1982-10-15
AU3606778A (en) 1979-11-15
ES469953A1 (es) 1979-09-16
AU8411782A (en) 1982-08-26
IE780940L (en) 1978-11-17
NL7805344A (nl) 1978-11-21
CH643233A5 (en) 1984-05-30
CH643238A5 (en) 1984-05-30
SE7805591L (sv) 1978-11-18
IT7849419A0 (it) 1978-05-17
FR2398718A1 (fr) 1979-02-23
JPH0112744B2 (sv) 1989-03-02
DE2821410A1 (de) 1978-11-30

Similar Documents

Publication Publication Date Title
IT1156755B (it) Derivati amminoalchilbenzenici utili come farmaceutici in particolare per la cura di ulcere gastriche e di allergie della pelle e relativo procedimento di produzione
IT7852280A0 (it) Procedimento per la produzione di derivati ammidici in particolare acilanilidi sostituite e prodotto ottenuto
IT1160853B (it) Derivati di feniletanolammina,particolarmente utili in terapia,e procedimento per la loro preparazione
IT1105040B (it) 3-1h-tetrazol-5-il-4h-pirido 1,2-a pirimidin-4-oni sostituiti utili in particolare come agenti terapeutici per inibire le reazioni allergiche e procedimento per la produzione dei detti derivati
IT1112112B (it) Derivati acilici sostituiti di amminoacidi e relativo procedimento di produzione
IT1053865B (it) Pasticca dolcificante effervescente e relativo procedimento di produzione
IT1111197B (it) Derivati della 3,4,5-triidrossipipe ridina,processi per la loro produzione e loro impiego
BR7807097A (pt) Processo para preparacao de derivados de imidazolidina,sua aplicacao,derivados de ureia e derivados de imidazolidina
IT7851499A0 (it) Procedimento per la produzione di derivati della xantina e prodotto relativo
IT7949849A0 (it) Procedimento per la produzione di derivati di pirimidone e prodotto ottenuto
IT1091176B (it) Nastro composito procedimento per la sua fabbricazione e sua applicazione alla produzione di imballaggi sterili
IT8267668A0 (it) Derivati dell ammidinopiperidina particolarmente utili come medicamenti e procedimento per la loro produzione
IT1052794B (it) Procedimento per la produzione di fibra proteica e prodotto ottenuto
IT1079696B (it) Prodotto per la cura della pelle
IT8848132A0 (it) Derivati della tiourea, loro preparazione e loro impiego come medicamenti
IT1040613B (it) Derivati di 2 ammino 1 3 tiazina e procedimento per la loro produzione
IT1040158B (it) Processo pr la produzione di glucosio isomerasi e prodottoottenuto
IT1098258B (it) Processo per la produzione di copolimeri e terpolimeri elastomerici e relativo prodotto
IT1105227B (it) Derivati di amminoacidi alfa-vinilici utili in particolare come composti farmaceutici e relativo procedimento di produzione
IT1107787B (it) Procedimento per la produzione di derivati di alcaloidi pentaciclici prodotto ottenuto e relativo procedimento di impiego nella sintesi di composti della eburnamenina
IT1105500B (it) Procedimento per la produzione di i-n-(omega-ammino-alfa-idrossialcanoil)amminoglicosidi utili in particolare come antibiotici e prodotto ottenuto
IT1107454B (it) Derivati alfa-alogenometilici di amminoacidi e relativo procedimento di produzione
IT1122391B (it) Derivati di idrochinone e relativo procedimento per la loro produzione
IT1107978B (it) Procedimento per la produzione di derivati di amminoacidi alfa-acetilenici e prodotto ottenuto
IT7849403A0 (it) Peptiche e di allergie della pelle derivati amminoalchiltiofenici uti e relativo procedimento di produzio li come composti farmaceutici in ne particolare per la cura di ulcere