IT1156058B - Composizione per trattamento del glaucoma - Google Patents
Composizione per trattamento del glaucomaInfo
- Publication number
- IT1156058B IT1156058B IT67796/82A IT6779682A IT1156058B IT 1156058 B IT1156058 B IT 1156058B IT 67796/82 A IT67796/82 A IT 67796/82A IT 6779682 A IT6779682 A IT 6779682A IT 1156058 B IT1156058 B IT 1156058B
- Authority
- IT
- Italy
- Prior art keywords
- alkenyl
- lower alkyl
- alkynyl
- hydroxyloweralkyl
- aralkyl
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 239000002876 beta blocker Substances 0.000 abstract 2
- 229940097320 beta blocking agent Drugs 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- -1 acetamido, amino Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005466 alkylenyl group Chemical group 0.000 abstract 1
- 230000001384 anti-glaucoma Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/276,658 US4454154A (en) | 1981-06-23 | 1981-06-23 | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8267796A0 IT8267796A0 (it) | 1982-06-22 |
| IT1156058B true IT1156058B (it) | 1987-01-28 |
Family
ID=23057573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT67796/82A IT1156058B (it) | 1981-06-23 | 1982-06-22 | Composizione per trattamento del glaucoma |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4454154A (it) |
| EP (1) | EP0082873B1 (it) |
| JP (1) | JPH0653663B2 (it) |
| AU (1) | AU565752B2 (it) |
| CA (1) | CA1188224A (it) |
| CH (1) | CH654205A5 (it) |
| ES (1) | ES8401928A1 (it) |
| GB (1) | GB2111387B (it) |
| GR (1) | GR76847B (it) |
| IL (1) | IL66070A (it) |
| IT (1) | IT1156058B (it) |
| NL (1) | NL8220252A (it) |
| NZ (1) | NZ200972A (it) |
| PH (1) | PH18970A (it) |
| SE (1) | SE462075B (it) |
| WO (1) | WO1983000014A1 (it) |
| ZA (1) | ZA824340B (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5135926A (en) * | 1984-03-14 | 1992-08-04 | Bodor Nicholas S | Soft β-adrenergic blocking agents |
| US5334601A (en) * | 1984-03-14 | 1994-08-02 | Bodor Nicholas S | Soft β-adrenergic blocking agents |
| US5202347A (en) * | 1984-03-14 | 1993-04-13 | Bodor Nicholas S | Soft β-adrenergic blocking agents |
| US4609663A (en) * | 1984-09-11 | 1986-09-02 | Alcon Laboratories, Inc. | Aldose reductase inhibitors useful in glaucoma therapy |
| DE3871596T3 (de) * | 1987-04-03 | 2000-09-07 | Pharmacia & Upjohn Ab, Stockholm | Anwendung eines Prostaglandins in Mischung mit einem adrenergischen Blocker zur Verminderung des Augen-Innendruckes. |
| CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US4857552A (en) * | 1988-06-08 | 1989-08-15 | E. I. Du Pont De Nemours And Co. | Stable pharmaceutical composition |
| US5536749A (en) * | 1994-10-13 | 1996-07-16 | Sl Pharmaceuticals, Inc. | Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents |
| US6197817B1 (en) | 1999-01-22 | 2001-03-06 | Selectus Pharmaceuticals, Inc. | Phenylpropionic acids and esters: compounds and methods for inducing beta-blockade for the treatment of cardiac disorders |
| EP1750693A4 (en) * | 2004-05-25 | 2010-06-02 | Othera Holding Inc | OKULOSELECTIVE MEDICINAL PRODUCTS AND PRODRUGS |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1593762A1 (de) * | 1967-02-06 | 1972-06-08 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen |
| US3868460A (en) * | 1967-02-06 | 1975-02-25 | Boehringer Sohn Ingelheim | Therapeutic compositions and method |
| US3740444A (en) * | 1968-01-25 | 1973-06-19 | Boehringer Sohn Ingelheim | Therapeutic compositions and method |
| GB1285038A (en) * | 1969-02-21 | 1972-08-09 | Ici Ltd | Alkanolamine derivatives |
| DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
| DE2048838A1 (de) * | 1970-10-05 | 1972-04-06 | C H Boehnnger Sohn, 6507 Ingel heim | Neue 1 Phenoxy 2 hydroxy 3 hydroxyal kylaminopropane und Verfahren zu ihrer Her stellung |
| FR2132570B1 (it) * | 1971-04-09 | 1974-08-02 | Lipha | |
| JPS4875539A (it) * | 1972-01-12 | 1973-10-11 | ||
| JPS49247A (it) * | 1972-04-17 | 1974-01-05 | ||
| US3839584A (en) * | 1972-08-31 | 1974-10-01 | Interx Research Corp | Pharmaceutical compositions containing a novel ester of ((methylamino)methyl)benzyl alcohol and methods of using same |
| AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
| US3825583A (en) * | 1973-04-26 | 1974-07-23 | Interx Research Corp | Ester of 3-hydroxy-alpha-((methylamino)methyl)benzyl alcohol |
| US4195085A (en) * | 1975-09-26 | 1980-03-25 | Merck & Co., Inc. | Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate |
| US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
| US4191765A (en) * | 1976-05-25 | 1980-03-04 | Hoechst Aktiengesellschaft | 1-Aryloxy-2-hydroxy-3-aminopropanes |
| US4080471A (en) * | 1976-06-25 | 1978-03-21 | Aktiebolaget Hassle | Use of substituted isopropylaminopropanols for inducing inotropic effects of the human heart |
| DE2752659A1 (de) * | 1976-12-07 | 1978-06-08 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
| US4127674A (en) * | 1977-03-21 | 1978-11-28 | Allergan Pharmaceuticals, Inc. | Method of treatment for glaucoma |
| EP0003664B1 (en) * | 1978-02-08 | 1982-02-17 | Imperial Chemical Industries Plc | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them |
| SE8004088L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ... |
| SE8004087L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ... |
| US4387103A (en) * | 1980-11-28 | 1983-06-07 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
-
1981
- 1981-06-23 US US06/276,658 patent/US4454154A/en not_active Expired - Fee Related
-
1982
- 1982-06-14 CA CA000405136A patent/CA1188224A/en not_active Expired
- 1982-06-14 PH PH27416A patent/PH18970A/en unknown
- 1982-06-15 NZ NZ200972A patent/NZ200972A/en unknown
- 1982-06-16 IL IL66070A patent/IL66070A/xx unknown
- 1982-06-18 GR GR68485A patent/GR76847B/el unknown
- 1982-06-18 ZA ZA824340A patent/ZA824340B/xx unknown
- 1982-06-22 IT IT67796/82A patent/IT1156058B/it active
- 1982-06-23 NL NL8220252A patent/NL8220252A/nl unknown
- 1982-06-23 WO PCT/US1982/000849 patent/WO1983000014A1/en active IP Right Grant
- 1982-06-23 ES ES513387A patent/ES8401928A1/es not_active Expired
- 1982-06-23 AU AU87374/82A patent/AU565752B2/en not_active Ceased
- 1982-06-23 GB GB08303061A patent/GB2111387B/en not_active Expired
- 1982-06-23 JP JP57502293A patent/JPH0653663B2/ja not_active Expired - Lifetime
- 1982-06-23 CH CH1102/83A patent/CH654205A5/de not_active IP Right Cessation
- 1982-06-23 EP EP82902333A patent/EP0082873B1/en not_active Expired
-
1983
- 1983-02-18 SE SE8300913A patent/SE462075B/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES513387A0 (es) | 1984-01-01 |
| GB2111387A (en) | 1983-07-06 |
| AU8737482A (en) | 1983-01-18 |
| GB8303061D0 (en) | 1983-03-09 |
| CA1188224A (en) | 1985-06-04 |
| NL8220252A (nl) | 1983-05-02 |
| JPS58500996A (ja) | 1983-06-23 |
| EP0082873A1 (en) | 1983-07-06 |
| NZ200972A (en) | 1986-10-08 |
| EP0082873A4 (en) | 1983-11-11 |
| SE462075B (sv) | 1990-05-07 |
| ES8401928A1 (es) | 1984-01-01 |
| JPH0653663B2 (ja) | 1994-07-20 |
| IL66070A (en) | 1987-03-31 |
| CH654205A5 (de) | 1986-02-14 |
| SE8300913D0 (sv) | 1983-02-18 |
| ZA824340B (en) | 1983-04-27 |
| EP0082873B1 (en) | 1988-12-07 |
| AU565752B2 (en) | 1987-09-24 |
| SE8300913L (en) | 1983-02-18 |
| PH18970A (en) | 1985-11-26 |
| GB2111387B (en) | 1986-02-05 |
| IT8267796A0 (it) | 1982-06-22 |
| US4454154A (en) | 1984-06-12 |
| IL66070A0 (en) | 1982-09-30 |
| GR76847B (it) | 1984-09-04 |
| WO1983000014A1 (en) | 1983-01-06 |
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