IT1154024B - Derivati pridinici e procedimento per la loro produzione - Google Patents

Derivati pridinici e procedimento per la loro produzione

Info

Publication number
IT1154024B
IT1154024B IT23375/82A IT2337582A IT1154024B IT 1154024 B IT1154024 B IT 1154024B IT 23375/82 A IT23375/82 A IT 23375/82A IT 2337582 A IT2337582 A IT 2337582A IT 1154024 B IT1154024 B IT 1154024B
Authority
IT
Italy
Prior art keywords
pridinical
derivatives
procedure
production
lopyridines
Prior art date
Application number
IT23375/82A
Other languages
English (en)
Italian (it)
Other versions
IT8223375A0 (it
Inventor
Giorgio Winters
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of IT8223375A0 publication Critical patent/IT8223375A0/it
Priority to IT23375/82A priority Critical patent/IT1154024B/it
Priority to GR72382A priority patent/GR78987B/el
Priority to DE8383108942T priority patent/DE3382299D1/de
Priority to EP83108942A priority patent/EP0104522B1/en
Priority to AT83108942T priority patent/ATE63913T1/de
Priority to US06/533,909 priority patent/US4612318A/en
Priority to ES83525786A priority patent/ES8503685A1/es
Priority to PT77370A priority patent/PT77370B/pt
Priority to CA000437174A priority patent/CA1248532A/en
Priority to JP58176193A priority patent/JPS5989679A/ja
Application granted granted Critical
Publication of IT1154024B publication Critical patent/IT1154024B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT23375/82A 1982-09-22 1982-09-22 Derivati pridinici e procedimento per la loro produzione IT1154024B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT23375/82A IT1154024B (it) 1982-09-22 1982-09-22 Derivati pridinici e procedimento per la loro produzione
GR72382A GR78987B (enExample) 1982-09-22 1983-09-05
AT83108942T ATE63913T1 (de) 1982-09-22 1983-09-10 Pyrazolo(3,4-b)pyridinderivate und verfahren zu ihrer herstellung.
EP83108942A EP0104522B1 (en) 1982-09-22 1983-09-10 New pyrazolo(3,4-b)pyridine derivatives and process for producing them
DE8383108942T DE3382299D1 (de) 1982-09-22 1983-09-10 Pyrazolo(3,4-b)pyridinderivate und verfahren zu ihrer herstellung.
US06/533,909 US4612318A (en) 1982-09-22 1983-09-19 CNS-depressant and analgesic tricyclo-[pyrazolo-[3,4-6]-pyridine] derivatives and pharmaceutical compositions thereof
ES83525786A ES8503685A1 (es) 1982-09-22 1983-09-21 Un procedimiento para preparar derivados de pirazolo (3,4-b) piridina
PT77370A PT77370B (en) 1982-09-22 1983-09-21 Process for preparing new pyrazolo <3,4-b> piridine derivatives and pharmaceutical preparations containing the same
CA000437174A CA1248532A (en) 1982-09-22 1983-09-21 Pyrazolo¬3,4-b|pyridine derivatives and process for producing them
JP58176193A JPS5989679A (ja) 1982-09-22 1983-09-22 ピラゾロ〔３，４−ｂ〕ピリジン誘導体類およびそれらの製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23375/82A IT1154024B (it) 1982-09-22 1982-09-22 Derivati pridinici e procedimento per la loro produzione

Publications (2)

Publication Number Publication Date
IT8223375A0 IT8223375A0 (it) 1982-09-22
IT1154024B true IT1154024B (it) 1987-01-21

Family

ID=11206534

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23375/82A IT1154024B (it) 1982-09-22 1982-09-22 Derivati pridinici e procedimento per la loro produzione

Country Status (10)

Country Link
US (1) US4612318A (enExample)
EP (1) EP0104522B1 (enExample)
JP (1) JPS5989679A (enExample)
AT (1) ATE63913T1 (enExample)
CA (1) CA1248532A (enExample)
DE (1) DE3382299D1 (enExample)
ES (1) ES8503685A1 (enExample)
GR (1) GR78987B (enExample)
IT (1) IT1154024B (enExample)
PT (1) PT77370B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ208555A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (3-amino-1h-pyrazol-4-yl)-arylmethanone derivatives
US4751226A (en) * 1985-09-12 1988-06-14 Fujisawa Pharmaceutical Co., Ltd. Pyrazoloisoquinoline derivatives, plant growth regulating compositions, and method of use therefor
JPH0615542B2 (ja) * 1986-07-22 1994-03-02 吉富製薬株式会社 ピラゾロピリジン化合物
WO1989003385A1 (fr) * 1987-10-13 1989-04-20 Yoshitomi Pharmaceutical Industries, Ltd. Composes de pyrazole fusionnes, procede de preparation et utilisation en medecine
TW370529B (en) 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
ES2135062T3 (es) * 1994-06-16 1999-10-16 Pfizer Pirazolo y pirrolopiridinas.
WO2001098301A1 (en) * 2000-06-20 2001-12-27 Japan Tobacco Inc. Pyrazolopyridine compounds and use thereof as drugs
JPWO2003020313A1 (ja) * 2001-09-04 2004-12-16 小野薬品工業株式会社 スフィンゴシン−１−リン酸受容体調節剤からなる呼吸器疾患治療剤
DK1522314T3 (da) * 2002-06-26 2014-05-26 Ono Pharmaceutical Co Midler for sygdomme forårsaget af vaskulær sammentrækning eller udvidelse
KR100844864B1 (ko) 2004-02-27 2008-07-09 에프. 호프만-라 로슈 아게 헤테로아릴-융합 피라졸로 유도체
CN1926139A (zh) * 2004-02-27 2007-03-07 霍夫曼-拉罗奇有限公司 稠合吡唑衍生物
KR20060114022A (ko) 2004-02-27 2006-11-03 에프. 호프만-라 로슈 아게 인다졸 유도체 및 그들을 함유하는 약학 조성물
JP2009506007A (ja) 2005-08-25 2009-02-12 エフ．ホフマン−ラ ロシュ アーゲー ｐ３８ＭＡＰキナーゼ阻害剤及びその使用方法
EP2468748B1 (en) * 2006-02-15 2016-05-25 AbbVie Inc. Pyrazoloquinolones are potent parp inhibitors
WO2010078427A1 (en) * 2008-12-30 2010-07-08 Arqule, Inc. Substituted pyrazolo [3, 4-b] pyridine compounds
CN102325755B (zh) 2008-12-30 2015-07-01 艾科尔公司 取代的5,6-二氢-6-苯基苯并[f]异喹啉-2-胺化合物
WO2011159864A1 (en) * 2010-06-17 2011-12-22 Bracco Imaging S.P.A. Jte013 analogs and methods of making and using same
RU2495039C1 (ru) * 2012-07-31 2013-10-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" МЕТИЛ 3-МЕТИЛ-5-[2-(4-АРИЛАМИНО)-2-ОКСОАЦЕТИЛ]-1,6-ДИФЕНИЛ-1Н-ПИРАЗОЛО[3,4-b]ПИРИДИН-4-КАРБОКСИЛАТЫ И МЕТИЛ 3-МЕТИЛ-5-[2-(4-АРИЛАМИНО)-2-ОКСОАЦЕТИЛ]-6-СТИРИЛ-1-ФЕНИЛ-1Н-ПИРАЗОЛО[3,4-b]ПИРИДИН-4-КАРБОКСИЛАТЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ
IL302355A (en) * 2017-08-23 2023-06-01 Sprint Bioscience Ab Azaindolylpyridone and diazaindolylpyridone compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3403158A (en) * 1966-03-11 1968-09-24 Upjohn Co 1h-pyrazolo[3, 4-b]pyridines
US3681368A (en) * 1970-10-15 1972-08-01 Abbott Lab Pyrazolo naphthridines
BE787249A (fr) * 1971-08-05 1973-02-05 Squibb & Sons Inc Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
US3891630A (en) * 1974-03-04 1975-06-24 Abbott Lab Substituted pyrazolo{8 3,4-e{9 {8 1,4{9 thiazepines and isoxazolo{8 5,4-e{9 {8 1,4{9 thiazepines
US3903096A (en) * 1974-03-29 1975-09-02 Squibb & Sons Inc New derivatives of sulfonyl-, sulfinyl- and sulfenyl-1H-pyrazolo {8 3,4-b{9 -pyridines
EP0005745B1 (en) * 1978-05-26 1982-07-14 Gruppo Lepetit S.P.A. Pyrazolo (3,4-c) and thiazolo (5,4-c) isoquinolines, methods for preparing them, these compounds for use as antiinflammatory, cns-depressant and anti-anxiety agents and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ATE63913T1 (de) 1991-06-15
IT8223375A0 (it) 1982-09-22
EP0104522A3 (en) 1985-06-19
GR78987B (enExample) 1984-10-02
JPS5989679A (ja) 1984-05-23
EP0104522A2 (en) 1984-04-04
PT77370A (en) 1983-10-01
CA1248532A (en) 1989-01-10
ES525786A0 (es) 1985-03-01
EP0104522B1 (en) 1991-05-29
ES8503685A1 (es) 1985-03-01
DE3382299D1 (de) 1991-07-04
PT77370B (en) 1986-04-21
US4612318A (en) 1986-09-16

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