IT1145330B - Composti di acidi 1-(aciltio)-e(mercapto)-1-ossoalchil-1,2,3,4-tetraidrochinolin-2-carbossilici dotati di attivita' anti-ipertensiva - Google Patents

Composti di acidi 1-(aciltio)-e(mercapto)-1-ossoalchil-1,2,3,4-tetraidrochinolin-2-carbossilici dotati di attivita' anti-ipertensiva

Info

Publication number
IT1145330B
IT1145330B IT47730/80A IT4773080A IT1145330B IT 1145330 B IT1145330 B IT 1145330B IT 47730/80 A IT47730/80 A IT 47730/80A IT 4773080 A IT4773080 A IT 4773080A IT 1145330 B IT1145330 B IT 1145330B
Authority
IT
Italy
Prior art keywords
tetraidrochinolin
ossoalchil
acylti
mercapto
carboxylic
Prior art date
Application number
IT47730/80A
Other languages
English (en)
Italian (it)
Other versions
IT8047730A0 (it
Inventor
George C Wright
David E Portlock
Original Assignee
Morton Norwich Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morton Norwich Products Inc filed Critical Morton Norwich Products Inc
Publication of IT8047730A0 publication Critical patent/IT8047730A0/it
Application granted granted Critical
Publication of IT1145330B publication Critical patent/IT1145330B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IT47730/80A 1979-02-07 1980-01-28 Composti di acidi 1-(aciltio)-e(mercapto)-1-ossoalchil-1,2,3,4-tetraidrochinolin-2-carbossilici dotati di attivita' anti-ipertensiva IT1145330B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1016579A 1979-02-07 1979-02-07
US06/090,862 US4461896A (en) 1979-02-07 1979-11-02 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids

Publications (2)

Publication Number Publication Date
IT8047730A0 IT8047730A0 (it) 1980-01-28
IT1145330B true IT1145330B (it) 1986-11-05

Family

ID=26680853

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47730/80A IT1145330B (it) 1979-02-07 1980-01-28 Composti di acidi 1-(aciltio)-e(mercapto)-1-ossoalchil-1,2,3,4-tetraidrochinolin-2-carbossilici dotati di attivita' anti-ipertensiva

Country Status (16)

Country Link
US (1) US4461896A (US20030157376A1-20030821-M00001.png)
AU (1) AU527887B2 (US20030157376A1-20030821-M00001.png)
CH (1) CH645355A5 (US20030157376A1-20030821-M00001.png)
DE (1) DE3004370A1 (US20030157376A1-20030821-M00001.png)
DK (1) DK152209C (US20030157376A1-20030821-M00001.png)
ES (1) ES488313A0 (US20030157376A1-20030821-M00001.png)
FR (1) FR2448533A1 (US20030157376A1-20030821-M00001.png)
GB (1) GB2042535B (US20030157376A1-20030821-M00001.png)
GR (1) GR74103B (US20030157376A1-20030821-M00001.png)
IE (1) IE49350B1 (US20030157376A1-20030821-M00001.png)
IL (1) IL59089A (US20030157376A1-20030821-M00001.png)
IT (1) IT1145330B (US20030157376A1-20030821-M00001.png)
NL (1) NL8000641A (US20030157376A1-20030821-M00001.png)
NZ (1) NZ192613A (US20030157376A1-20030821-M00001.png)
PT (1) PT70793A (US20030157376A1-20030821-M00001.png)
SE (1) SE436031B (US20030157376A1-20030821-M00001.png)

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Publication number Priority date Publication date Assignee Title
US4595675A (en) * 1979-09-19 1986-06-17 Hoechst Aktiengesellschaft Bicyclic α-iminocarboxylic acid compounds having hypotensive activity
DE2937779A1 (de) * 1979-09-19 1981-04-09 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
DE3044236A1 (de) * 1980-11-25 1982-06-16 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
US4599357A (en) * 1979-12-17 1986-07-08 Ciba-Geigy Corporation 1-mercaptoalkanoylindoline-2-carboxylic acids
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
EP0046953B1 (de) * 1980-08-30 1989-12-06 Hoechst Aktiengesellschaft Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4390700A (en) 1980-11-10 1983-06-28 Ciba-Geigy Corporation 1-Carboxyazaalkanoyl-tetrahydroquinoline-2-carboxylic acids
US4401818A (en) 1980-12-24 1983-08-30 Ciba-Geigy Corporation 1-Carboxyalkanoyl-1,2,3,4-tetrahydroquinoline-2-carboxylic acids
DE3276311D1 (en) * 1981-02-17 1987-06-19 Warner Lambert Co Octahydro-2-(omega-mercaptoalkanoyl)3-oxo-1h-isoindole-1-carboxylic acids and esters
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374246A (en) * 1981-06-18 1983-02-15 Norwich Eaton Pharmaceuticals, Inc. 1-N-[(1-Carboxy-3-phenylpropyl)glycyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid compounds
US5356890A (en) * 1988-06-15 1994-10-18 Brigham And Women's Hospital S-nitroso derivatives of ace inhibitors and the use thereof
US5025001A (en) * 1988-06-15 1991-06-18 Brigham And Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
US5187183A (en) * 1988-06-15 1993-02-16 Brigham & Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
US5644055A (en) * 1993-06-30 1997-07-01 Ciba-Geigy Corporation Antihypertensive tricyclic azepine derivatives useful as inhibitors of enkephalinase and ACE
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
US8916550B2 (en) * 2005-05-09 2014-12-23 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
TWI401254B (zh) * 2005-05-09 2013-07-11 Hydra Biosciences Inc 用於調節trpv3功能之化合物
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US7998980B2 (en) 2006-09-15 2011-08-16 Hydra Biosciences, Inc. Compounds for modulating TRPV3 function
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
WO2013009998A2 (en) 2011-07-12 2013-01-17 Pursuit Vascular, Inc. Device for delivery of antimicrobial agent into trans-dermal catheter
EP3137122B1 (en) 2014-05-02 2019-09-04 Excelsior Medical Corporation Strip package for antiseptic cap
JP6822978B2 (ja) 2015-05-08 2021-01-27 アイシーユー・メディカル・インコーポレーテッド 治療薬のエミッタを受け入れるように構成された医療用コネクタ
CA3040277A1 (en) 2016-10-14 2018-04-19 Icu Medical, Inc. Sanitizing caps for medical connectors
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
AU2019384564B2 (en) 2018-11-21 2023-11-23 Icu Medical, Inc. Antimicrobial device comprising a cap with ring and insert
AU2021212754A1 (en) 2020-01-29 2022-08-04 Kamari Pharma Ltd. Compounds and compositions for use in treating skin disorders
CA3204371A1 (en) 2020-12-07 2022-06-16 Icu Medical, Inc. Peritoneal dialysis caps, systems and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR837847A (fr) * 1937-05-13 1939-02-21 Ste Ind Chim Bale Agents auxiliaires pour l'impression
US4104392A (en) * 1974-11-08 1978-08-01 Mitsubishi Chemical Industries Ltd. N2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof, and antithrombotic compositions and methods employing them
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
AU4091178A (en) * 1977-10-25 1980-04-24 Merck & Co Inc Substituted mercapto acid amides

Also Published As

Publication number Publication date
DK152209B (da) 1988-02-08
NL8000641A (nl) 1980-08-11
SE436031B (sv) 1984-11-05
DK51280A (da) 1980-08-08
IT8047730A0 (it) 1980-01-28
IE800014L (en) 1980-08-07
FR2448533A1 (fr) 1980-09-05
DE3004370A1 (de) 1980-08-14
ES8102559A1 (es) 1981-01-16
DK152209C (da) 1988-06-20
GB2042535A (en) 1980-09-24
IE49350B1 (en) 1985-09-18
IL59089A0 (en) 1980-05-30
AU527887B2 (en) 1983-03-31
NZ192613A (en) 1981-10-19
ES488313A0 (es) 1981-01-16
SE8000209L (sv) 1980-08-08
DE3004370C2 (US20030157376A1-20030821-M00001.png) 1989-10-26
US4461896A (en) 1984-07-24
IL59089A (en) 1982-08-31
AU5472780A (en) 1980-08-14
FR2448533B1 (US20030157376A1-20030821-M00001.png) 1983-01-07
PT70793A (en) 1980-03-01
GB2042535B (en) 1983-01-26
GR74103B (US20030157376A1-20030821-M00001.png) 1984-06-06
CH645355A5 (de) 1984-09-28

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