IT1133054B - Derivati dell alcool particolarmente utili come antidiabetici e procedimento per la loro preparazione - Google Patents
Derivati dell alcool particolarmente utili come antidiabetici e procedimento per la loro preparazioneInfo
- Publication number
- IT1133054B IT1133054B IT67134/80A IT6713480A IT1133054B IT 1133054 B IT1133054 B IT 1133054B IT 67134/80 A IT67134/80 A IT 67134/80A IT 6713480 A IT6713480 A IT 6713480A IT 1133054 B IT1133054 B IT 1133054B
- Authority
- IT
- Italy
- Prior art keywords
- diabetics
- procedure
- preparation
- particularly useful
- alcohol derivatives
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical class CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP54010562A JPS6010021B2 (ja) | 1979-01-31 | 1979-01-31 | 新規ベンジルアルコ−ル誘導体及びその製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8067134A0 IT8067134A0 (it) | 1980-01-30 |
| IT1133054B true IT1133054B (it) | 1986-07-09 |
Family
ID=11753672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT67134/80A IT1133054B (it) | 1979-01-31 | 1980-01-30 | Derivati dell alcool particolarmente utili come antidiabetici e procedimento per la loro preparazione |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4276304A (it) |
| JP (1) | JPS6010021B2 (it) |
| BE (1) | BE881419A (it) |
| CH (1) | CH646136A5 (it) |
| DE (1) | DE3003505A1 (it) |
| FR (1) | FR2447904B1 (it) |
| GB (1) | GB2042525B (it) |
| IT (1) | IT1133054B (it) |
| NL (1) | NL8000589A (it) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2555574B2 (fr) * | 1979-07-13 | 1986-11-14 | Lafon Labor | Derives de 2-amino-1-(methoxyphenyl)-1-ethanol utiles en tant que medicaments |
| US4404222A (en) * | 1980-08-25 | 1983-09-13 | American Cyanamid Company | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby |
| US4407819A (en) * | 1980-08-25 | 1983-10-04 | American Cyanamid Company | Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals |
| US4432995A (en) * | 1980-12-22 | 1984-02-21 | American Cyanamid Company | 5-[2-(Ethylamino)-1-hydroxylethyl] anthranilonitrile and the use thereof in meat producing animals |
| EP0070134B1 (en) * | 1981-07-11 | 1985-11-13 | Beecham Group Plc | Secondary phenyl ethanol amines and their pharmaceutical use |
| CH653322A5 (de) * | 1982-12-01 | 1985-12-31 | Siegfried Ag | Verfahren zur herstellung von phenylethanolaminen. |
| US5530029A (en) * | 1987-09-15 | 1996-06-25 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
| US5552442A (en) * | 1987-09-15 | 1996-09-03 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
| US4871873A (en) * | 1988-03-18 | 1989-10-03 | Merck & Company Incorporated | Process for synthesis of arylglyoxal arylimines |
| US5151439A (en) * | 1990-05-04 | 1992-09-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| US5106867A (en) * | 1990-05-04 | 1992-04-21 | American Cyanamid Company | Method of increasing lean meat in edible animals |
| US5061727A (en) * | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| US5245053A (en) * | 1990-05-04 | 1993-09-14 | American Cyanamid Company | Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles |
| US5482971A (en) * | 1993-10-01 | 1996-01-09 | American Cyanamid Company | Beta3 -adrenergic agents and their use in pharmaceutical compositions |
| SV2002000522A (es) | 2000-07-13 | 2002-10-24 | Lilly Co Eli | Agosnistas adrenergicos beta3 ref. x-13921 |
| AU2002234134A1 (en) | 2000-11-10 | 2002-05-21 | Eli Lilly And Company | 3-substituted oxindole beta 3 agonists |
| ATE340794T1 (de) * | 2001-08-14 | 2006-10-15 | Lilly Co Eli | Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes |
| ATE325119T1 (de) * | 2001-08-14 | 2006-06-15 | Lilly Co Eli | 3-substituierte oxindol-beta-3-agonisten |
| ATE386740T1 (de) * | 2001-11-20 | 2008-03-15 | Lilly Co Eli | Beta-3 adrenergische agonisten |
| ATE297925T1 (de) * | 2001-11-20 | 2005-07-15 | Lilly Co Eli | 3-substituierte oxindol beta 3 agonisten |
| JP2005520805A (ja) * | 2002-01-11 | 2005-07-14 | イーライ・リリー・アンド・カンパニー | ２−オキソ−ベンズイミダゾリル置換型エタノールアミン誘導体およびβ３アゴニストとしてのその使用 |
| CN110172028A (zh) * | 2019-05-27 | 2019-08-27 | 安徽恒星制药有限公司 | 一种工业化生产妥洛特罗的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1541394A (fr) * | 1966-10-18 | 1968-10-04 | Boehringer Sohn Ingelheim | Procédé de fabrication de nouvelles 3, 4-dihydroxyphénylalcanolamines |
| JPS516657B1 (it) * | 1970-08-07 | 1976-03-01 | ||
| US3700692A (en) * | 1971-06-04 | 1972-10-24 | Colgate Palmolive Co | 1-(4{40 -hydroxy-3{40 -(hydroxy methyl)-phenyl)-1-hydroxy-2-aralkylaminoethanes |
| JPS5310974B2 (it) * | 1974-06-10 | 1978-04-18 | ||
| JPS5271428A (en) * | 1975-12-11 | 1977-06-14 | Tanabe Seiyaku Co Ltd | Preparation of benzylalcohol derivatives |
| GB1535435A (en) * | 1975-12-11 | 1978-12-13 | Tanabe Seiyaku Co | Benzyl alcohol derivatives |
| JPS53149940A (en) * | 1977-06-02 | 1978-12-27 | Tanabe Seiyaku Co Ltd | Novel benzyl alcohol derivatives and their preparation |
| ZA791403B (en) * | 1978-04-10 | 1980-05-28 | Draco Ab | Composition of matter |
-
1979
- 1979-01-31 JP JP54010562A patent/JPS6010021B2/ja not_active Expired
-
1980
- 1980-01-18 US US06/113,218 patent/US4276304A/en not_active Expired - Lifetime
- 1980-01-28 GB GB8002802A patent/GB2042525B/en not_active Expired
- 1980-01-29 BE BE6/47068A patent/BE881419A/fr not_active IP Right Cessation
- 1980-01-30 FR FR8002013A patent/FR2447904B1/fr not_active Expired
- 1980-01-30 IT IT67134/80A patent/IT1133054B/it active
- 1980-01-30 CH CH74180A patent/CH646136A5/de not_active IP Right Cessation
- 1980-01-30 NL NL8000589A patent/NL8000589A/nl not_active Application Discontinuation
- 1980-01-31 DE DE19803003505 patent/DE3003505A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| GB2042525A (en) | 1980-09-24 |
| FR2447904B1 (fr) | 1986-03-28 |
| BE881419A (fr) | 1980-05-16 |
| CH646136A5 (de) | 1984-11-15 |
| JPS6010021B2 (ja) | 1985-03-14 |
| IT8067134A0 (it) | 1980-01-30 |
| NL8000589A (nl) | 1980-08-04 |
| GB2042525B (en) | 1982-12-08 |
| JPS55102546A (en) | 1980-08-05 |
| FR2447904A1 (fr) | 1980-08-29 |
| DE3003505A1 (de) | 1980-08-14 |
| US4276304A (en) | 1981-06-30 |
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