IT1130554B - Mercapto acil-derivati della prolina e dell'acido pipecolico cheto-sostituti - Google Patents

Info

Publication number

IT1130554B

IT1130554B IT20743/80A IT2074380A IT1130554B IT 1130554 B IT1130554 B IT 1130554B IT 20743/80 A IT20743/80 A IT 20743/80A IT 2074380 A IT2074380 A IT 2074380A IT 1130554 B IT1130554 B IT 1130554B

Authority

IT

Italy

Prior art keywords

pipecolic acid

mercapto

alkyl

lower alkyl

acid derivs

Prior art date

1980-03-18

Links

• Espacenet
• Global Dossier
• Discuss

• HXEACLLIILLPRG-YFKPBYRVSA-N L-pipecolic acid Chemical compound [O-]C(=O)[C@@H]1CCCC[NH2+]1 HXEACLLIILLPRG-YFKPBYRVSA-N 0.000 title abstract 2
• ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 title abstract 2
• HXEACLLIILLPRG-RXMQYKEDSA-N l-pipecolic acid Natural products OC(=O)[C@H]1CCCCN1 HXEACLLIILLPRG-RXMQYKEDSA-N 0.000 title abstract 2
• 125000000217 alkyl group Chemical group 0.000 abstract 5
• 102000005862 Angiotensin II Human genes 0.000 abstract 1
• 101800000734 Angiotensin-1 Proteins 0.000 abstract 1
• 102400000344 Angiotensin-1 Human genes 0.000 abstract 1
• 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
• 101100097467 Arabidopsis thaliana SYD gene Proteins 0.000 abstract 1
• CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
• 101100495925 Schizosaccharomyces pombe (strain 972 / ATCC 24843) chr3 gene Proteins 0.000 abstract 1
• 125000004414 alkyl thio group Chemical group 0.000 abstract 1
• ORWYRWWVDCYOMK-HBZPZAIKSA-N angiotensin I Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C1=CC=C(O)C=C1 ORWYRWWVDCYOMK-HBZPZAIKSA-N 0.000 abstract 1
• 229950006323 angiotensin ii Drugs 0.000 abstract 1
• 229940030600 antihypertensive agent Drugs 0.000 abstract 1
• 239000002220 antihypertensive agent Substances 0.000 abstract 1
• 238000006243 chemical reaction Methods 0.000 abstract 1
• 125000001475 halogen functional group Chemical group 0.000 abstract 1
• 125000000623 heterocyclic group Chemical group 0.000 abstract 1
• 230000007062 hydrolysis Effects 0.000 abstract 1
• 238000006460 hydrolysis reaction Methods 0.000 abstract 1
• ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
• 150000003839 salts Chemical class 0.000 abstract 1