IT1127384B - Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazione - Google Patents
Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazioneInfo
- Publication number
- IT1127384B IT1127384B IT48062/80A IT4806280A IT1127384B IT 1127384 B IT1127384 B IT 1127384B IT 48062/80 A IT48062/80 A IT 48062/80A IT 4806280 A IT4806280 A IT 4806280A IT 1127384 B IT1127384 B IT 1127384B
- Authority
- IT
- Italy
- Prior art keywords
- mercaptoacyldii
- hypothensive
- dropirazol
- derivatives
- activity
- Prior art date
Links
- 150000001735 carboxylic acids Chemical class 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/018,548 US4211786A (en) | 1979-03-08 | 1979-03-08 | Mercaptoacyldihydropyrazole carboxylic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8048062A0 IT8048062A0 (it) | 1980-03-03 |
| IT1127384B true IT1127384B (it) | 1986-05-21 |
Family
ID=21788501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48062/80A IT1127384B (it) | 1979-03-08 | 1980-03-03 | Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazione |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4211786A (en:Method) |
| JP (1) | JPS55122766A (en:Method) |
| AU (1) | AU534582B2 (en:Method) |
| BE (1) | BE882133A (en:Method) |
| CA (1) | CA1137497A (en:Method) |
| CH (1) | CH645630A5 (en:Method) |
| DE (1) | DE3008904A1 (en:Method) |
| DK (1) | DK99980A (en:Method) |
| FR (1) | FR2450820A1 (en:Method) |
| GB (1) | GB2048850B (en:Method) |
| IE (1) | IE49541B1 (en:Method) |
| IT (1) | IT1127384B (en:Method) |
| LU (1) | LU82223A1 (en:Method) |
| NL (1) | NL8001349A (en:Method) |
| SE (1) | SE450382B (en:Method) |
| ZA (1) | ZA801016B (en:Method) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| US4331806A (en) * | 1979-07-30 | 1982-05-25 | E. R. Squibb & Sons, Inc. | Dithioacyldihydropyrazole carboxylic acid derivatives |
| US4288368A (en) * | 1979-07-30 | 1981-09-08 | E. R. Squibb & Sons, Inc. | Dithioacylproline derivatives |
| CA1156236A (en) * | 1979-10-25 | 1983-11-01 | George C. Rovnyak | Mercaptoacyldihydropyrazole carboxylic acid derivatives |
| US4266065A (en) * | 1980-04-14 | 1981-05-05 | E. R. Squibb & Sons, Inc. | Mercaptoacyldihydropyrazole carboxylic acid derivatives |
| US4254267A (en) * | 1979-10-25 | 1981-03-03 | E. R. Squibb & Sons, Inc. | Mercaptoacyldihydropyrazole carboxylic acid derivatives |
| US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
| US4312990A (en) * | 1980-09-11 | 1982-01-26 | E. R. Squibb & Sons, Inc. | 1-Mercaptoacyl-3-[(aminosulfonyl) phenyl]-4,5-dihydro-1H-pyrazole-5-carboxylic acid |
| US4371526A (en) * | 1981-08-21 | 1983-02-01 | E. R. Squibb & Sons, Inc. | Phosphinylalkanoyl substituted 4,5-dihydropyrazole-5-carboxylic acid derivatives and hypotensive method and composition |
| JPS58133376U (ja) * | 1982-03-05 | 1983-09-08 | 吉原 靖人 | バツテイング練習用バツト |
| US4470973A (en) * | 1982-07-19 | 1984-09-11 | E. R. Squibb & Sons, Inc. | Substituted peptide compounds |
| US4742067A (en) * | 1982-07-22 | 1988-05-03 | E. R. Squibb & Sons, Inc. | Acylalkylaminocarbonyl substituted amino and imino acid compounds |
| US4621092A (en) * | 1982-07-22 | 1986-11-04 | E. R. Squibb & Sons, Inc. | Substituted proline compounds, composition and method of use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| US4053651A (en) * | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| ZA777062B (en) * | 1976-12-03 | 1979-02-28 | Squibb & Sons Inc | Derivatives of thiazolidinecarboxylic acids and related acids |
| US4129566A (en) * | 1978-02-15 | 1978-12-12 | E. R. Squibb & Sons, Inc. | Derivatives of dehydrocyclicimino acids |
-
1979
- 1979-03-08 US US06/018,548 patent/US4211786A/en not_active Expired - Lifetime
-
1980
- 1980-02-15 CA CA000345726A patent/CA1137497A/en not_active Expired
- 1980-02-22 AU AU55822/80A patent/AU534582B2/en not_active Ceased
- 1980-02-22 ZA ZA00801016A patent/ZA801016B/xx unknown
- 1980-03-03 IT IT48062/80A patent/IT1127384B/it active
- 1980-03-05 LU LU82223A patent/LU82223A1/de unknown
- 1980-03-06 IE IE449/80A patent/IE49541B1/en not_active IP Right Cessation
- 1980-03-06 NL NL8001349A patent/NL8001349A/nl not_active Application Discontinuation
- 1980-03-06 CH CH177180A patent/CH645630A5/de not_active IP Right Cessation
- 1980-03-07 DK DK99980A patent/DK99980A/da not_active Application Discontinuation
- 1980-03-07 DE DE19803008904 patent/DE3008904A1/de not_active Ceased
- 1980-03-07 BE BE0/199718A patent/BE882133A/fr not_active IP Right Cessation
- 1980-03-07 FR FR8005217A patent/FR2450820A1/fr active Granted
- 1980-03-07 SE SE8001818A patent/SE450382B/sv not_active IP Right Cessation
- 1980-03-07 GB GB8007914A patent/GB2048850B/en not_active Expired
- 1980-03-08 JP JP2971480A patent/JPS55122766A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| LU82223A1 (de) | 1980-09-24 |
| IE49541B1 (en) | 1985-10-30 |
| DE3008904A1 (de) | 1980-09-18 |
| FR2450820A1 (fr) | 1980-10-03 |
| AU5582280A (en) | 1980-09-11 |
| IT8048062A0 (it) | 1980-03-03 |
| SE450382B (sv) | 1987-06-22 |
| IE800449L (en) | 1980-09-08 |
| CA1137497A (en) | 1982-12-14 |
| JPS55122766A (en) | 1980-09-20 |
| FR2450820B1 (en:Method) | 1983-04-22 |
| JPH0141628B2 (en:Method) | 1989-09-06 |
| US4211786A (en) | 1980-07-08 |
| NL8001349A (nl) | 1980-09-10 |
| GB2048850B (en) | 1983-04-27 |
| CH645630A5 (de) | 1984-10-15 |
| BE882133A (fr) | 1980-09-08 |
| DK99980A (da) | 1980-09-09 |
| GB2048850A (en) | 1980-12-17 |
| AU534582B2 (en) | 1984-02-09 |
| SE8001818L (sv) | 1980-09-09 |
| ZA801016B (en) | 1981-02-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19930315 |