IT1116516B - Metronidazolo fosfato suoi sali e relativo procedimento di preparazione - Google Patents

Metronidazolo fosfato suoi sali e relativo procedimento di preparazione

Info

Publication number
IT1116516B
IT1116516B IT47874/79A IT4787479A IT1116516B IT 1116516 B IT1116516 B IT 1116516B IT 47874/79 A IT47874/79 A IT 47874/79A IT 4787479 A IT4787479 A IT 4787479A IT 1116516 B IT1116516 B IT 1116516B
Authority
IT
Italy
Prior art keywords
salts
preparation procedure
related preparation
metronidazole phosphate
metronidazole
Prior art date
Application number
IT47874/79A
Other languages
English (en)
Italian (it)
Other versions
IT7947874A0 (it
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IT7947874A0 publication Critical patent/IT7947874A0/it
Application granted granted Critical
Publication of IT1116516B publication Critical patent/IT1116516B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT47874/79A 1978-02-06 1979-02-02 Metronidazolo fosfato suoi sali e relativo procedimento di preparazione IT1116516B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/875,393 US4160827A (en) 1978-02-06 1978-02-06 Metronidazole phosphate and salts

Publications (2)

Publication Number Publication Date
IT7947874A0 IT7947874A0 (it) 1979-02-02
IT1116516B true IT1116516B (it) 1986-02-10

Family

ID=25365724

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47874/79A IT1116516B (it) 1978-02-06 1979-02-02 Metronidazolo fosfato suoi sali e relativo procedimento di preparazione

Country Status (16)

Country Link
US (1) US4160827A (en, 2012)
JP (1) JPS54115375A (en, 2012)
AU (1) AU523423B2 (en, 2012)
BE (1) BE873973A (en, 2012)
CA (1) CA1108622A (en, 2012)
CH (1) CH638535A5 (en, 2012)
DE (1) DE2903269A1 (en, 2012)
ES (1) ES477265A1 (en, 2012)
FR (1) FR2416234A1 (en, 2012)
GB (1) GB2013683B (en, 2012)
GR (1) GR67623B (en, 2012)
IT (1) IT1116516B (en, 2012)
NL (1) NL7900858A (en, 2012)
PH (1) PH14464A (en, 2012)
SE (1) SE445221B (en, 2012)
ZA (1) ZA79282B (en, 2012)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386079A (en) * 1981-11-23 1983-05-31 The Upjohn Company Method of treating depression
US4531004A (en) * 1981-11-23 1985-07-23 The Upjohn Company Dimetronidazole phosphates
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
US7223421B2 (en) * 2000-06-30 2007-05-29 Mcneil-Ppc, Inc. Teste masked pharmaceutical particles
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US6423707B1 (en) 2000-08-28 2002-07-23 California Pacific Medical Center Nitroimidazole ester analogues and therapeutic applications
EP1305008A4 (en) * 2001-03-27 2005-02-09 R P Scherer Technologies Inc A IMPROVED FORMS OF PHARMACEUTICALLY ACTIVE AGENTS AND PROCESS FOR THE PRODUCTION THEREOF
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
GB0315671D0 (en) * 2003-07-04 2003-08-13 Chelsea And Westminster Nhs Tr Improvements in or relating to organic compounds
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
DE602004017214D1 (de) * 2003-10-28 2008-11-27 Ems Sa Antibakterielle und/oder gegen protozoen wirksame nitroimidazolderivatverbindungen mit ureasehemmender wirkung, verfahren zur herstellung dieser verbindungen und deren verwendung in pharmazeutischen zusammensetzungen und medikamenten
JP2008540511A (ja) 2005-05-09 2008-11-20 フォーミックス エルティーディー． 糖類発泡性組成物
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
AU2009205314A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2776366C (en) 2009-10-02 2017-07-18 Foamix Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
CN102516299A (zh) * 2011-12-09 2012-06-27 陕西合成药业有限公司 左旋奥硝唑磷酸酯氨基酸盐及其制备方法和用途
CN102516298A (zh) * 2011-12-09 2012-06-27 陕西合成药业有限公司 左旋奥硝唑磷酸酯稳定的药用盐及其制备方法和用途
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
CN108295039A (zh) * 2018-02-28 2018-07-20 重庆希尔安药业有限公司 甲硝唑阴道泡腾片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE571291A (fr) * 1957-09-20 1962-01-12 Rhone Poulenc Sa Nouveaux derives de l'imidazole et leur preparation.
US2944061A (en) * 1957-09-20 1960-07-05 Acyl derivatives and process
GB1280355A (en) * 1969-06-20 1972-07-05 Rech S Et D Applic Scient Et M Substituted 5-nitro-imidazoles and their preparation
FR2054504B1 (en, 2012) * 1969-07-18 1973-06-08 Rhone Poulenc Sa
US3910945A (en) * 1972-10-04 1975-10-07 Searle & Co 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl-N-arylalkyldithiocarbamates
US3882136A (en) * 1973-11-16 1975-05-06 Searle & Co S-{8 omega-(1-imidazolyl) alkyl{9 hydrogen monothiosulfates and salts thereof

Also Published As

Publication number Publication date
US4160827A (en) 1979-07-10
AU4370579A (en) 1979-08-16
GR67623B (en, 2012) 1981-09-01
ZA79282B (en) 1980-01-30
CA1108622A (en) 1981-09-08
IT7947874A0 (it) 1979-02-02
FR2416234B1 (en, 2012) 1983-02-04
NL7900858A (nl) 1979-08-08
JPS54115375A (en) 1979-09-07
FR2416234A1 (fr) 1979-08-31
DE2903269A1 (de) 1979-08-09
GB2013683A (en) 1979-08-15
GB2013683B (en) 1982-06-30
ES477265A1 (es) 1980-10-01
BE873973A (fr) 1979-08-06
PH14464A (en) 1981-07-29
CH638535A5 (de) 1983-09-30
SE7900952L (sv) 1979-08-07
SE445221B (sv) 1986-06-09
AU523423B2 (en) 1982-07-29

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