IT1068217B - Omocisteina tiolattone 6 cloro nicotinamide - Google Patents

Omocisteina tiolattone 6 cloro nicotinamide

Info

Publication number
IT1068217B
IT1068217B IT51734/76A IT5173476A IT1068217B IT 1068217 B IT1068217 B IT 1068217B IT 51734/76 A IT51734/76 A IT 51734/76A IT 5173476 A IT5173476 A IT 5173476A IT 1068217 B IT1068217 B IT 1068217B
Authority
IT
Italy
Prior art keywords
tiolactone
homocystein
nicotinamide
chlorine
homocystein tiolactone
Prior art date
Application number
IT51734/76A
Other languages
English (en)
Inventor
Paolo De Witt
M Teresa Ramacci
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT51734/76A priority Critical patent/IT1068217B/it
Priority to IE1645/77A priority patent/IE45365B1/en
Priority to IN1234/CAL/77A priority patent/IN145767B/en
Priority to AU27868/77A priority patent/AU506922B2/en
Priority to AR268995A priority patent/AR214527A1/es
Priority to ES462110A priority patent/ES462110A1/es
Priority to BE180705A priority patent/BE858443A/xx
Priority to CA286,093A priority patent/CA1078388A/en
Priority to DE19772740345 priority patent/DE2740345A1/de
Priority to NL7709938A priority patent/NL7709938A/xx
Priority to CH1140877A priority patent/CH629201A5/it
Priority to AT670977A priority patent/AT361925B/de
Priority to FR7728396A priority patent/FR2367764A1/fr
Priority to US05/837,529 priority patent/US4167572A/en
Priority to DK439277A priority patent/DK439277A/da
Priority to JP12135877A priority patent/JPS5350178A/ja
Priority to EG583/77A priority patent/EG13219A/xx
Priority to SE7711347A priority patent/SE423545B/sv
Priority to FI773001A priority patent/FI62303C/fi
Priority to GR54549A priority patent/GR63598B/el
Priority to PH20325A priority patent/PH13068A/en
Priority to NO773506A priority patent/NO148714C/no
Priority to PT67155A priority patent/PT67155B/pt
Priority to GB42890/77A priority patent/GB1587273A/en
Priority to ZA00776157A priority patent/ZA776157B/xx
Application granted granted Critical
Publication of IT1068217B publication Critical patent/IT1068217B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
IT51734/76A 1976-10-14 1976-10-14 Omocisteina tiolattone 6 cloro nicotinamide IT1068217B (it)

Priority Applications (25)

Application Number Priority Date Filing Date Title
IT51734/76A IT1068217B (it) 1976-10-14 1976-10-14 Omocisteina tiolattone 6 cloro nicotinamide
IE1645/77A IE45365B1 (en) 1976-10-14 1977-08-05 Homocysteine thiolactone derivatives
IN1234/CAL/77A IN145767B (it) 1976-10-14 1977-08-09
AU27868/77A AU506922B2 (en) 1976-10-14 1977-08-12 N-6-chlorunicotinoyl-d, l-homocysteing thiolactonne
AR268995A AR214527A1 (es) 1976-10-14 1977-08-30 Procedimiento para la preparacion de-n-6-cloronicotionoil-d,1 homocisteina tiolactona
ES462110A ES462110A1 (es) 1976-10-14 1977-09-03 Procedimiento para la preparacion de tiolactona de n-6-clo- ronicotinoil-d,1-homocisteina.
BE180705A BE858443A (fr) 1976-10-14 1977-09-06 6-chloro-nicotinamide d'homocysteine thiolactone et sa preparation
CA286,093A CA1078388A (en) 1976-10-14 1977-09-06 N-6-chloronicotinoyl-d, l-homocysteine thiolactone
DE19772740345 DE2740345A1 (de) 1976-10-14 1977-09-07 N-6-chlornicotinoyl-d, 1-homocysteinthiolacton und verfahren zu seiner herstellung
NL7709938A NL7709938A (nl) 1976-10-14 1977-09-09 Gesubstitueerd homocysteine, farmacologisch aan- vaardbare zouten daarvan, werkwijze voor het be- reiden van deze verbindingen, alsmede werkwijze voor het bereiden van een op deze verbindingen gebaseerd geneesmiddel met antilipolytische en lever-beschermende werking.
AT670977A AT361925B (de) 1976-10-14 1977-09-19 Verfahren zur herstellung des neuen n-6-chlor- nicothinoyl-d,1-homocysteinthiolactons und dessen salzen
CH1140877A CH629201A5 (it) 1976-10-14 1977-09-19 Procedimento per la preparazione di omocisteina tiolattone 6-cloro-nicotinamide.
FR7728396A FR2367764A1 (fr) 1976-10-14 1977-09-21 Homocysteine-thiolactone-6-chloro-nicotinamide et ses sels, et son procede de preparation
US05/837,529 US4167572A (en) 1976-10-14 1977-09-28 N-6-Chloronicotinoyl-d,l-homocysteine thiolactone
DK439277A DK439277A (da) 1976-10-14 1977-10-04 N-6-chlornicotinoyl-d,1-homocysteinthiolacton samt fremgangsmaade til fremstilling heraf
JP12135877A JPS5350178A (en) 1976-10-14 1977-10-07 Production of nn66 chloronicotynoyl homocysteine thiolactone
EG583/77A EG13219A (en) 1976-10-14 1977-10-09 Process for preparing of n-6-chloronicotinayl d,l-homocysteine thiolactone
SE7711347A SE423545B (sv) 1976-10-14 1977-10-10 Analogiforfarande for framstellning av n-6-kloronikotinoyl-d,l-homocysteintiolakton
FI773001A FI62303C (fi) 1976-10-14 1977-10-11 Foerfarande foer framstaellning av en antilipolytiskt aktiv ny-6-klornikotinyl-d,1-homocystein-tiolakton
GR54549A GR63598B (en) 1976-10-14 1977-10-11 Method of preparation of n-6-chloranicotinoylo-ocmocisteino-thiolactone
PH20325A PH13068A (en) 1976-10-14 1977-10-11 N,-6-chloronicotinoyl-d,1-homocysteine thiolactone
NO773506A NO148714C (no) 1976-10-14 1977-10-13 Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-6-klornikotinoyl-d,1-homocystein-thiolacton
PT67155A PT67155B (fr) 1976-10-14 1977-10-14 Procede pour la preparation de tiolactone-n-6-chlore-nicotinamide-d,l-homocisteine
GB42890/77A GB1587273A (en) 1976-10-14 1977-10-14 Homocysteine derivatives
ZA00776157A ZA776157B (en) 1976-10-14 1978-05-23 N-6-chloronicotinoyl-d,1-homocysteine thiolactone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT51734/76A IT1068217B (it) 1976-10-14 1976-10-14 Omocisteina tiolattone 6 cloro nicotinamide

Publications (1)

Publication Number Publication Date
IT1068217B true IT1068217B (it) 1985-03-21

Family

ID=11275646

Family Applications (1)

Application Number Title Priority Date Filing Date
IT51734/76A IT1068217B (it) 1976-10-14 1976-10-14 Omocisteina tiolattone 6 cloro nicotinamide

Country Status (25)

Country Link
US (1) US4167572A (it)
JP (1) JPS5350178A (it)
AR (1) AR214527A1 (it)
AT (1) AT361925B (it)
AU (1) AU506922B2 (it)
BE (1) BE858443A (it)
CA (1) CA1078388A (it)
CH (1) CH629201A5 (it)
DE (1) DE2740345A1 (it)
DK (1) DK439277A (it)
EG (1) EG13219A (it)
ES (1) ES462110A1 (it)
FI (1) FI62303C (it)
FR (1) FR2367764A1 (it)
GB (1) GB1587273A (it)
GR (1) GR63598B (it)
IE (1) IE45365B1 (it)
IN (1) IN145767B (it)
IT (1) IT1068217B (it)
NL (1) NL7709938A (it)
NO (1) NO148714C (it)
PH (1) PH13068A (it)
PT (1) PT67155B (it)
SE (1) SE423545B (it)
ZA (1) ZA776157B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1215238B (it) * 1985-02-22 1990-01-31 Chiesi Farma Spa Derivati di omocisteina tiolattone,loro procedimento di preparazione e formulazioni farmaceutiche
WO1992000964A1 (en) * 1990-07-05 1992-01-23 Nippon Soda Co., Ltd. Amine derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1134683B (de) * 1961-03-16 1962-08-16 Degussa Verfahren zur Herstellung von N-Acylhomocysteinthiolacton
US4021433A (en) * 1973-03-08 1977-05-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Derivative of nicotinic acid with amides
IT1056031B (it) * 1973-03-08 1982-01-30 Sigma Tau Ind Farmaceuti Redivati ammidici dell acido nicotininico

Also Published As

Publication number Publication date
NO773506L (no) 1978-04-17
US4167572A (en) 1979-09-11
FR2367764B1 (it) 1980-09-05
NO148714B (no) 1983-08-22
NO148714C (no) 1983-11-30
PT67155B (fr) 1979-03-19
CA1078388A (en) 1980-05-27
IN145767B (it) 1978-12-16
SE7711347L (sv) 1978-04-15
BE858443A (fr) 1978-01-02
ES462110A1 (es) 1978-06-01
NL7709938A (nl) 1978-04-18
DK439277A (da) 1978-04-15
AU506922B2 (en) 1980-01-31
AU2786877A (en) 1979-02-15
AT361925B (de) 1981-04-10
IE45365B1 (en) 1982-08-11
AR214527A1 (es) 1979-06-29
GB1587273A (en) 1981-04-01
FI62303B (fi) 1982-08-31
PT67155A (fr) 1977-11-01
JPS5350178A (en) 1978-05-08
FR2367764A1 (fr) 1978-05-12
FI62303C (fi) 1982-12-10
ATA670977A (de) 1980-09-15
EG13219A (en) 1980-12-31
GR63598B (en) 1979-11-26
ZA776157B (en) 1978-07-26
IE45365L (en) 1978-04-14
FI773001A (fi) 1978-04-15
DE2740345A1 (de) 1978-04-20
CH629201A5 (it) 1982-04-15
PH13068A (en) 1979-11-23
SE423545B (sv) 1982-05-10

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