IS8344A - Útskipt þíófen og notkun þeirra - Google Patents
Útskipt þíófen og notkun þeirraInfo
- Publication number
- IS8344A IS8344A IS8344A IS8344A IS8344A IS 8344 A IS8344 A IS 8344A IS 8344 A IS8344 A IS 8344A IS 8344 A IS8344 A IS 8344A IS 8344 A IS8344 A IS 8344A
- Authority
- IS
- Iceland
- Prior art keywords
- thiophene
- replacement
- thiophene replacement
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49558003P | 2003-08-15 | 2003-08-15 | |
| US57641604P | 2004-05-28 | 2004-05-28 | |
| PCT/GB2004/003473 WO2005016909A1 (en) | 2003-08-15 | 2004-08-12 | Substituted thiophenes and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS8344A true IS8344A (is) | 2006-03-09 |
Family
ID=34198049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS8344A IS8344A (is) | 2003-08-15 | 2006-03-09 | Útskipt þíófen og notkun þeirra |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7423061B2 (is) |
| EP (1) | EP1660474B1 (is) |
| JP (1) | JP2007502308A (is) |
| KR (1) | KR20060080918A (is) |
| AR (1) | AR045459A1 (is) |
| AT (1) | ATE412645T1 (is) |
| AU (1) | AU2004265140A1 (is) |
| BR (1) | BRPI0413585A (is) |
| CA (1) | CA2535652A1 (is) |
| DE (1) | DE602004017478D1 (is) |
| ES (1) | ES2314443T3 (is) |
| HK (1) | HK1091487A1 (is) |
| IL (1) | IL173619A0 (is) |
| IS (1) | IS8344A (is) |
| MX (1) | MXPA06001775A (is) |
| NO (1) | NO20060718L (is) |
| RU (1) | RU2006107782A (is) |
| TW (1) | TW200524894A (is) |
| WO (1) | WO2005016909A1 (is) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10360369A1 (de) * | 2003-12-22 | 2005-07-14 | Bayer Cropscience Ag | Amide |
| EP1732920B1 (en) * | 2004-01-05 | 2011-03-09 | AstraZeneca AB | Thiophene derivatives as chk 1 inhibitors |
| DE102005035742A1 (de) * | 2005-07-29 | 2007-02-01 | Merck Patent Gmbh | Quadratsäurederivate II |
| DE102005039541A1 (de) * | 2005-08-22 | 2007-03-22 | Merck Patent Gmbh | 3-Oxo-indazol-quadratsäurederivate |
| US20090005375A1 (en) * | 2007-03-30 | 2009-01-01 | Edcon Chang | Acetyl coenzyme a carboxylase inhibitors |
| CN101481380B (zh) * | 2008-01-08 | 2012-10-17 | 浙江医药股份有限公司新昌制药厂 | 噻吩并哒嗪类化合物及其制备方法、药物组合物及其用途 |
| WO2009096198A1 (ja) * | 2008-02-01 | 2009-08-06 | Pharma Ip Limited Liability Intermediary Corporations | 新規ビアリール誘導体 |
| CA2725755A1 (en) * | 2008-06-11 | 2009-12-17 | Genentech, Inc. | Substituted pyrroles and methods of use |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
| JP7407298B2 (ja) * | 2020-03-04 | 2023-12-28 | ファロス・アイバイオ・カンパニー・リミテッド | ２，３，５－置換されたチオフェン化合物の卵巣癌の予防、改善または治療用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002500650A (ja) * | 1997-05-23 | 2002-01-08 | バイエル、コーポレイション | Ｒａｆキナーゼ阻害剤 |
| CA2290520C (en) | 1997-05-23 | 2009-01-27 | Bayer Corporation | Inhibition of p38 kinase activity by aryl ureas |
| GB0003154D0 (en) | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
| US6414013B1 (en) | 2000-06-19 | 2002-07-02 | Pharmacia & Upjohn S.P.A. | Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention |
| EP1324759A4 (en) | 2000-10-12 | 2004-05-12 | Smithkline Beecham Corp | NF - G (K) B INHIBITORS |
| UA76977C2 (en) * | 2001-03-02 | 2006-10-16 | Icos Corp | Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers |
| SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
| WO2003028731A1 (en) | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
| JP2005506334A (ja) | 2001-10-04 | 2005-03-03 | スミスクライン・ビーチャム・コーポレイション | ＮＦ−κＢ阻害剤 |
| WO2003029241A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
| WO2003104218A1 (en) | 2002-06-06 | 2003-12-18 | Smithkline Beecham Corporation | Nf-:b inhibitors |
| US20060116419A1 (en) | 2002-12-06 | 2006-06-01 | Callahan James F | Nf-kb inhibitors |
| SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
| US20050085531A1 (en) | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
| EP1732920B1 (en) | 2004-01-05 | 2011-03-09 | AstraZeneca AB | Thiophene derivatives as chk 1 inhibitors |
| WO2005105777A1 (en) | 2004-05-05 | 2005-11-10 | Pharmacia & Upjohn Company Llc | Substituted thiophene amide compounds for the treatment of inflammation |
| JP2008523071A (ja) | 2004-12-07 | 2008-07-03 | ルーカス ファーマシューティカルズ， インコーポレイテッド | Ｍａｐキナーゼの尿素インヒビター |
| EP1824843A2 (en) | 2004-12-07 | 2007-08-29 | Locus Pharmaceuticals, Inc. | Inhibitors of protein kinases |
-
2004
- 2004-08-12 DE DE602004017478T patent/DE602004017478D1/de not_active Expired - Fee Related
- 2004-08-12 AU AU2004265140A patent/AU2004265140A1/en not_active Abandoned
- 2004-08-12 RU RU2006107782/04A patent/RU2006107782A/ru not_active Application Discontinuation
- 2004-08-12 AT AT04768043T patent/ATE412645T1/de not_active IP Right Cessation
- 2004-08-12 US US10/568,380 patent/US7423061B2/en not_active Expired - Fee Related
- 2004-08-12 EP EP04768043A patent/EP1660474B1/en active Active
- 2004-08-12 KR KR1020067003164A patent/KR20060080918A/ko not_active Application Discontinuation
- 2004-08-12 BR BRPI0413585-7A patent/BRPI0413585A/pt not_active Application Discontinuation
- 2004-08-12 WO PCT/GB2004/003473 patent/WO2005016909A1/en active Search and Examination
- 2004-08-12 CA CA002535652A patent/CA2535652A1/en not_active Abandoned
- 2004-08-12 ES ES04768043T patent/ES2314443T3/es active Active
- 2004-08-12 MX MXPA06001775A patent/MXPA06001775A/es not_active Application Discontinuation
- 2004-08-12 JP JP2006523673A patent/JP2007502308A/ja active Pending
- 2004-08-13 TW TW093124393A patent/TW200524894A/zh unknown
- 2004-08-17 AR ARP040102946A patent/AR045459A1/es unknown
-
2006
- 2006-02-08 IL IL173619A patent/IL173619A0/en unknown
- 2006-02-14 NO NO20060718A patent/NO20060718L/no not_active Application Discontinuation
- 2006-03-09 IS IS8344A patent/IS8344A/is unknown
- 2006-11-01 HK HK06112029.4A patent/HK1091487A1/xx not_active IP Right Cessation
-
2008
- 2008-09-08 US US12/206,317 patent/US20090054396A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060080918A (ko) | 2006-07-11 |
| MXPA06001775A (es) | 2006-05-17 |
| ES2314443T3 (es) | 2009-03-16 |
| US7423061B2 (en) | 2008-09-09 |
| IL173619A0 (en) | 2006-07-05 |
| AR045459A1 (es) | 2005-10-26 |
| WO2005016909A1 (en) | 2005-02-24 |
| ATE412645T1 (de) | 2008-11-15 |
| BRPI0413585A (pt) | 2006-10-17 |
| TW200524894A (en) | 2005-08-01 |
| HK1091487A1 (en) | 2007-01-19 |
| AU2004265140A1 (en) | 2005-02-24 |
| JP2007502308A (ja) | 2007-02-08 |
| US20060281666A1 (en) | 2006-12-14 |
| EP1660474A1 (en) | 2006-05-31 |
| CA2535652A1 (en) | 2005-02-24 |
| US20090054396A1 (en) | 2009-02-26 |
| NO20060718L (no) | 2006-03-01 |
| EP1660474B1 (en) | 2008-10-29 |
| DE602004017478D1 (de) | 2008-12-11 |
| RU2006107782A (ru) | 2006-08-10 |
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