IS5008A - C-peptíð insúlíns - Google Patents

C-peptíð insúlíns

Info

Publication number
IS5008A
IS5008A IS5008A IS5008A IS5008A IS 5008 A IS5008 A IS 5008A IS 5008 A IS5008 A IS 5008A IS 5008 A IS5008 A IS 5008A IS 5008 A IS5008 A IS 5008A
Authority
IS
Iceland
Prior art keywords
peptides
atpase activity
peptide
fragment
sequence
Prior art date
Application number
IS5008A
Other languages
English (en)
Inventor
Wahren John
Johansson Bo-Lennart
Jörnvall Hans
Original Assignee
Creative Peptides Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creative Peptides Sweden Ab filed Critical Creative Peptides Sweden Ab
Publication of IS5008A publication Critical patent/IS5008A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IS5008A 1996-09-27 1999-03-23 C-peptíð insúlíns IS5008A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9603533A SE520392C2 (sv) 1996-09-27 1996-09-27 Specifika peptider för behandling av diabetes mellitus
PCT/GB1997/002627 WO1998013384A1 (en) 1996-09-27 1997-09-26 Insulin c-peptides

Publications (1)

Publication Number Publication Date
IS5008A true IS5008A (is) 1999-03-23

Family

ID=20404052

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5008A IS5008A (is) 1996-09-27 1999-03-23 C-peptíð insúlíns

Country Status (24)

Country Link
US (1) US6610649B2 (is)
EP (1) EP0938503B1 (is)
JP (1) JP2001500893A (is)
KR (1) KR20000048643A (is)
AT (1) ATE347562T1 (is)
AU (1) AU741901B2 (is)
BG (1) BG103362A (is)
BR (1) BR9711573A (is)
CA (1) CA2266416C (is)
CZ (1) CZ108599A3 (is)
DE (1) DE69737065T2 (is)
DK (1) DK0938503T3 (is)
ES (1) ES2278394T3 (is)
HU (1) HUP0000432A3 (is)
IL (1) IL129143A0 (is)
IS (1) IS5008A (is)
NO (1) NO991483L (is)
NZ (1) NZ335231A (is)
PL (1) PL332494A1 (is)
RU (1) RU2206336C2 (is)
SE (1) SE520392C2 (is)
SK (1) SK39499A3 (is)
TR (1) TR199900694T2 (is)
WO (1) WO1998013384A1 (is)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0022342D0 (en) * 2000-09-12 2000-10-25 Creative Peptides Sweden Ab Reduction of the electrocardiographic QT interval
DE10055857A1 (de) * 2000-11-10 2002-08-22 Creative Peptides Sweden Ab Dj Neue pharmazeutische Depotformulierung
US20030198666A1 (en) * 2002-01-07 2003-10-23 Richat Abbas Oral insulin therapy
US7384914B2 (en) * 2003-01-06 2008-06-10 Emisphere Technologies, Inc. Night-time oral insulin therapy
US20050026826A1 (en) * 2003-01-17 2005-02-03 Margarethe Hoenig Feline proinsulin, insulin and constituent peptides
US20050203001A1 (en) * 2004-03-05 2005-09-15 Emisphere Technologies, Inc. Oral insulin therapies and protocol
GB0323979D0 (en) 2003-10-13 2003-11-19 Creative Peptides Sweden Ab Therapeutic applications for c-peptide
US7557081B2 (en) * 2004-05-27 2009-07-07 Essential Skincare, Llc Alpha-1-acid glycoprotein for the treatment of diabetes
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
GB0601950D0 (en) * 2006-01-31 2006-03-15 Creative Peptides Sweden Ab Compositions and methods of treating diabetes
US9505823B2 (en) * 2006-08-07 2016-11-29 TEV A Biopharmaceuticals USA, Inc. Albumin-insulin fusion proteins
KR20100057640A (ko) * 2007-09-11 2010-05-31 몬도바이오테크 래보래토리즈 아게 치료제로서의 인슐린 c-펩티드 단독 또는 glp-1과의 배합물의 용도
GB0723250D0 (en) * 2007-11-28 2008-01-09 Univ Leeds Compositions and methods for reducing macrovascular complications in diabetic patients
EP2350118B1 (en) 2008-09-19 2016-03-30 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
EP2334338A2 (en) * 2008-09-19 2011-06-22 Nektar Therapeutics Polymer conjugates of c-peptides
US8410049B2 (en) * 2009-10-28 2013-04-02 Cebix Methods and kits for preventing hypoglycemia
EP2571896A4 (en) 2010-05-17 2014-01-08 Cebix Inc PEGYLATED C-PEPTIDE
CN105617351A (zh) 2011-02-11 2016-06-01 密歇根大学董事会 肽组合物和用于治疗患者的方法
WO2013075117A2 (en) 2011-11-17 2013-05-23 John Wahren Pegylated c-peptide
RU2522897C1 (ru) * 2013-04-16 2014-07-20 Закрытое акционерное общество "ФАРМ-ХОЛДИНГ" Твердая кишечнорастворимая лекарственная форма с-пептида проинсулина для перорального применения (варианты) и способ ее получения (варианты)
KR101676542B1 (ko) * 2014-12-30 2016-11-16 건국대학교 산학협력단 프로인슐린의 면역학적 용도
CN104888201B (zh) * 2015-06-29 2018-04-27 齐锦生 用于防治糖尿病及其慢性并发症的肽类药物
EP3577462B1 (en) 2017-02-06 2024-04-17 Resiliun B.V. Interaction between c-peptides and elastin receptor, a model for understanding vascular disease

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU166913B (is) * 1972-05-15 1975-06-28
JPS5210872B2 (is) * 1973-07-14 1977-03-26
JPS55105653A (en) * 1978-10-02 1980-08-13 Shionogi & Co Ltd Tyrosyl c-peptides
CH650679A5 (de) 1981-08-27 1985-08-15 Lilly Co Eli Gegen diabetes mellitus wirksames pharmazeutisches mittel.
DE3326473A1 (de) 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
US4581165A (en) 1984-06-14 1986-04-08 Eli Lilly And Company Anti-diabetic compounds
US5104854A (en) 1989-02-01 1992-04-14 Washington University Antiviral peptides
NZ232375A (en) 1989-02-09 1992-04-28 Lilly Co Eli Insulin analogues modified at b29
US5364757A (en) 1990-05-21 1994-11-15 Administrators Of The Tulane Educational Fund Methods of supporting a diagnosis of systemic lupus erythematosus
IL99699A (en) * 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
JPH05268982A (ja) 1992-03-27 1993-10-19 Hoechst Japan Ltd 骨形成作用を有する新規な蛋白質およびその製造法
JPH07509221A (ja) 1992-04-13 1995-10-12 オクラホマ メディカル リサーチ ファウンデーション 自己抗体診断用の方法および試薬
WO1994025071A1 (en) 1993-05-05 1994-11-10 Keith Rose Polyoxime compounds and their preparation
AT400723B (de) 1993-08-27 1996-03-25 Biomay Prod & Handel Rekombinante alternaria alternata allergene
MX9700198A (es) 1994-07-08 1997-04-30 Dartmouth College Compuestos peptidos de proinsulina para detectar y tratar diabetes tipo 1.
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
GB9422175D0 (en) 1994-11-03 1994-12-21 Univ Dundee Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof
GB9509164D0 (en) 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds
AU728186B2 (en) 1996-03-15 2001-01-04 Corixa Corporation Compounds and methods for immunotherapy and immunodiagnosis of prostate cancer
US6150500A (en) 1996-07-12 2000-11-21 Salerno; John C. Activators of endothelial nitric oxide synthase

Also Published As

Publication number Publication date
AU4391597A (en) 1998-04-17
CA2266416A1 (en) 1998-04-02
EP0938503A1 (en) 1999-09-01
AU741901B2 (en) 2001-12-13
RU2206336C2 (ru) 2003-06-20
EP0938503B1 (en) 2006-12-06
SK39499A3 (en) 1999-10-08
TR199900694T2 (xx) 1999-06-21
ES2278394T3 (es) 2007-08-01
SE9603533D0 (sv) 1996-09-27
ATE347562T1 (de) 2006-12-15
DE69737065T2 (de) 2007-06-28
JP2001500893A (ja) 2001-01-23
HUP0000432A2 (hu) 2000-08-28
CZ108599A3 (cs) 1999-08-11
BG103362A (en) 2000-05-31
SE9603533L (sv) 1998-03-28
DK0938503T3 (da) 2007-04-10
US6610649B2 (en) 2003-08-26
PL332494A1 (en) 1999-09-13
SE520392C2 (sv) 2003-07-01
US20020107175A1 (en) 2002-08-08
KR20000048643A (ko) 2000-07-25
NO991483L (no) 1999-05-18
NZ335231A (en) 2000-11-24
NO991483D0 (no) 1999-03-26
BR9711573A (pt) 2000-01-18
IL129143A0 (en) 2000-02-17
HUP0000432A3 (en) 2000-10-30
CA2266416C (en) 2008-04-29
DE69737065D1 (en) 2007-01-18
WO1998013384A1 (en) 1998-04-02

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