IN2015DN03854A - - Google Patents

Download PDF

Info

Publication number
IN2015DN03854A
IN2015DN03854A IN3854DEN2015A IN2015DN03854A IN 2015DN03854 A IN2015DN03854 A IN 2015DN03854A IN 3854DEN2015 A IN3854DEN2015 A IN 3854DEN2015A IN 2015DN03854 A IN2015DN03854 A IN 2015DN03854A
Authority
IN
India
Prior art keywords
methods
formula
administering
relates
present
Prior art date
Application number
Other languages
English (en)
Inventor
James Wallace Sleigh
William Alexander Denny
Jiney Jose
Swarnalatha Akuratiya Gamage
Martyn Gregory Harvey
Logan James Voss
Original Assignee
Auckland Uniservices Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auckland Uniservices Ltd filed Critical Auckland Uniservices Ltd
Publication of IN2015DN03854A publication Critical patent/IN2015DN03854A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/14Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
IN3854DEN2015 2012-10-08 2013-10-08 IN2015DN03854A (OSRAM)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ60288512 2012-10-08
NZ61120213 2013-05-28
PCT/IB2013/059191 WO2014057414A1 (en) 2012-10-08 2013-10-08 Ketamine derivatives

Publications (1)

Publication Number Publication Date
IN2015DN03854A true IN2015DN03854A (OSRAM) 2015-10-02

Family

ID=50476991

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3854DEN2015 IN2015DN03854A (OSRAM) 2012-10-08 2013-10-08

Country Status (13)

Country Link
US (3) US20150259277A1 (OSRAM)
EP (1) EP2903963A4 (OSRAM)
JP (2) JP6309957B2 (OSRAM)
KR (1) KR20150065873A (OSRAM)
CN (1) CN104837810B (OSRAM)
AU (1) AU2013328280B2 (OSRAM)
BR (1) BR112015007647A2 (OSRAM)
CA (1) CA2922340A1 (OSRAM)
EA (1) EA201590697A1 (OSRAM)
HK (1) HK1212673A1 (OSRAM)
IN (1) IN2015DN03854A (OSRAM)
MX (1) MX2015004362A (OSRAM)
WO (1) WO2014057414A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1212673A1 (zh) * 2012-10-08 2016-06-17 奥克兰服务有限公司 氯胺酮衍生物
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
HK1248578A1 (zh) 2015-06-27 2018-10-19 Shenox Pharmaceuticals, Llc 氯胺酮透皮递送系统
US11827606B2 (en) 2015-11-18 2023-11-28 Spirify Pharma Inc. Phenyl cyclohexanone derivatives and methods of making and using them
US11111210B2 (en) 2015-11-18 2021-09-07 Spirify Pharma Inc. Phenyl cyclohexanone derivatives and methods of making and using them
CN115108927A (zh) * 2016-03-25 2022-09-27 美国政府健康及人类服务部 (2r,6r)-羟基去甲氯胺酮和(2s,6s)-羟基去甲氯胺酮的晶型和合成方法
AU2019206950B2 (en) 2018-01-10 2021-07-01 XWPharma Ltd. Prodrugs of ketamine, compositions and uses thereof
WO2019186357A1 (en) * 2018-03-26 2019-10-03 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
JP7534960B2 (ja) 2018-06-04 2024-08-15 ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ (2r,6r)-ヒドロキシノルケタミンの合成および精製のためのプロセス
CN112125816A (zh) * 2020-03-17 2020-12-25 国药集团工业有限公司 一种氯胺酮、其衍生物或其盐的消旋化方法
DE102021105268A1 (de) * 2021-03-04 2022-09-08 Lts Lohmann Therapie-Systeme Ag. Oraler Dünnfilm
US11690811B2 (en) 2021-08-13 2023-07-04 XWPharma Ltd. Pharmaceutical compositions and oral dosage forms of ketamine derivatives
CN115677444A (zh) * 2022-10-26 2023-02-03 公安部第三研究所 同位素毒品代谢物标记化合物及其制备方法、用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254124A (en) * 1962-06-29 1966-05-31 Parke Davis & Co Aminoketones and methods for their production
GB1134146A (en) * 1967-09-15 1968-11-20 Parke Davis & Co New organic amines and methods for their production
US5019583A (en) 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
US5466700A (en) 1993-08-30 1995-11-14 Glaxo Wellcome Inc. Anesthetic use of N-phenyl-N-(4-piperidinyl)amides
US5866591A (en) 1996-09-11 1999-02-02 Glaxo Wellcome Inc. Stable formulations of remifentanil
US20040254182A1 (en) * 2000-01-28 2004-12-16 Mulvihill Mark Joseph Enhanced propertied pharmaceuticals
US20040248963A1 (en) 2001-11-23 2004-12-09 Bueno Melendo Ana Belen Prodrugs of excitatory amino acids
DE60335428D1 (de) 2002-01-31 2011-02-03 Randox Lab Ltd Immunogene, Antikörper und Konjugate für Ketamin und dessen Metaboliten
NZ540282A (en) * 2002-11-18 2008-06-30 Yaupon Therapeutics Inc Analgesic uses of norketamine and ketamine/norketamine prodrugs
CA2620374C (en) * 2005-09-28 2012-12-11 Thomas Meyer Pharmaceutical compositions for the treatment of inner ear disorders
WO2008134525A1 (en) 2007-04-26 2008-11-06 Auspex Pharmaeuticals, Inc. Deuterium labelled ketamine
AU2012323845B9 (en) * 2011-10-14 2017-06-29 Sri International The use of (2R, 6R)-hydroxynorketamine, (S)-dehydronorketamine and other stereoisomeric dehydro and hydroxylated metabolites of (R,S)- ketamine in the treatment of depression and neuropathic pain
HK1212673A1 (zh) * 2012-10-08 2016-06-17 奥克兰服务有限公司 氯胺酮衍生物

Also Published As

Publication number Publication date
EA201590697A1 (ru) 2015-09-30
AU2013328280B2 (en) 2017-12-21
JP2018127466A (ja) 2018-08-16
MX2015004362A (es) 2015-12-08
EP2903963A1 (en) 2015-08-12
BR112015007647A2 (pt) 2017-07-04
WO2014057414A9 (en) 2014-12-18
US20190169113A1 (en) 2019-06-06
HK1212673A1 (zh) 2016-06-17
KR20150065873A (ko) 2015-06-15
WO2014057414A1 (en) 2014-04-17
JP6309957B2 (ja) 2018-04-11
US20170190653A1 (en) 2017-07-06
CN104837810B (zh) 2019-08-06
US20150259277A1 (en) 2015-09-17
CA2922340A1 (en) 2014-04-17
CN104837810A (zh) 2015-08-12
JP2015535847A (ja) 2015-12-17
AU2013328280A1 (en) 2015-05-14
US10239825B2 (en) 2019-03-26
EP2903963A4 (en) 2016-05-25

Similar Documents

Publication Publication Date Title
IN2015DN03854A (OSRAM)
MX2014009757A (es) Derivados de isoindolina, composiciones farmaceuticas que los contienen y su uso en terapia.
PH12015501385A1 (en) Autotaxin inhibitors
PH12013501600A1 (en) Novel heterocyclic derivatives
IN2014MN00988A (OSRAM)
TN2014000175A1 (en) Novel purine derivatives and their use in the treatment of disease
IN2014MN00948A (OSRAM)
MX2013011908A (es) Composiciones y usos terapeuticos de inhibidores de cinasa epsilon relacionados con cinasa i-kappa b (ikk) y cinasa 1 de union tank.
IN2014MN00987A (OSRAM)
IN2014MN00986A (OSRAM)
IN2014MN02049A (OSRAM)
MY191358A (en) Triazolopyrazines as brd4 inhibitors for use in the treatment of cancer
IN2014DN09434A (OSRAM)
PH12014501514A1 (en) New azetidine derivatives, pharmaceutical compositions and uses thereof
IN2014MN02069A (OSRAM)
PH12015500713B1 (en) Acylaminopyrimidine derivatives for the treatment of viral infections and further diseases
IN2012MN02591A (OSRAM)
NZ608116A (en) Triazine-oxadiazoles
PH12013500007A1 (en) Piperidine derivatives and their use for the treatment of metabolic disorders
MX344238B (es) Compuestos de tetrazol y métodos para preparar y usar los mismos.
MX2014006004A (es) Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia.
MX2015011614A (es) Derivados de pirrolidina, composiciones farmaceuticas que los contienen, y su uso en terapia.
IN2015DN03998A (OSRAM)
MX2016004934A (es) Derivados de aminotetralina y aminoindano, composiciones farmaceuticas que los contienen, y su uso en terapia.
GB2523707A (en) Novel pharmaceutical formulations and their use in the treatment of periodontal disease