MX2015004362A - Derivados de ketamina. - Google Patents
Derivados de ketamina.Info
- Publication number
- MX2015004362A MX2015004362A MX2015004362A MX2015004362A MX2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A
- Authority
- MX
- Mexico
- Prior art keywords
- ketamine derivatives
- methods
- derivatives
- ketamine
- formula
- Prior art date
Links
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical class C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/14—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ60288512 | 2012-10-08 | ||
| NZ61120213 | 2013-05-28 | ||
| PCT/IB2013/059191 WO2014057414A1 (en) | 2012-10-08 | 2013-10-08 | Ketamine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015004362A true MX2015004362A (es) | 2015-12-08 |
Family
ID=50476991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015004362A MX2015004362A (es) | 2012-10-08 | 2013-10-08 | Derivados de ketamina. |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20150259277A1 (OSRAM) |
| EP (1) | EP2903963A4 (OSRAM) |
| JP (2) | JP6309957B2 (OSRAM) |
| KR (1) | KR20150065873A (OSRAM) |
| CN (1) | CN104837810B (OSRAM) |
| AU (1) | AU2013328280B2 (OSRAM) |
| BR (1) | BR112015007647A2 (OSRAM) |
| CA (1) | CA2922340A1 (OSRAM) |
| EA (1) | EA201590697A1 (OSRAM) |
| HK (1) | HK1212673A1 (OSRAM) |
| IN (1) | IN2015DN03854A (OSRAM) |
| MX (1) | MX2015004362A (OSRAM) |
| WO (1) | WO2014057414A1 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1212673A1 (zh) * | 2012-10-08 | 2016-06-17 | 奥克兰服务有限公司 | 氯胺酮衍生物 |
| US20160332962A1 (en) * | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| HK1248578A1 (zh) | 2015-06-27 | 2018-10-19 | Shenox Pharmaceuticals, Llc | 氯胺酮透皮递送系统 |
| US11827606B2 (en) | 2015-11-18 | 2023-11-28 | Spirify Pharma Inc. | Phenyl cyclohexanone derivatives and methods of making and using them |
| US11111210B2 (en) | 2015-11-18 | 2021-09-07 | Spirify Pharma Inc. | Phenyl cyclohexanone derivatives and methods of making and using them |
| CN115108927A (zh) * | 2016-03-25 | 2022-09-27 | 美国政府健康及人类服务部 | (2r,6r)-羟基去甲氯胺酮和(2s,6s)-羟基去甲氯胺酮的晶型和合成方法 |
| AU2019206950B2 (en) | 2018-01-10 | 2021-07-01 | XWPharma Ltd. | Prodrugs of ketamine, compositions and uses thereof |
| WO2019186357A1 (en) * | 2018-03-26 | 2019-10-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
| JP7534960B2 (ja) | 2018-06-04 | 2024-08-15 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | （２ｒ，６ｒ）－ヒドロキシノルケタミンの合成および精製のためのプロセス |
| CN112125816A (zh) * | 2020-03-17 | 2020-12-25 | 国药集团工业有限公司 | 一种氯胺酮、其衍生物或其盐的消旋化方法 |
| DE102021105268A1 (de) * | 2021-03-04 | 2022-09-08 | Lts Lohmann Therapie-Systeme Ag. | Oraler Dünnfilm |
| US11690811B2 (en) | 2021-08-13 | 2023-07-04 | XWPharma Ltd. | Pharmaceutical compositions and oral dosage forms of ketamine derivatives |
| CN115677444A (zh) * | 2022-10-26 | 2023-02-03 | 公安部第三研究所 | 同位素毒品代谢物标记化合物及其制备方法、用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3254124A (en) * | 1962-06-29 | 1966-05-31 | Parke Davis & Co | Aminoketones and methods for their production |
| GB1134146A (en) * | 1967-09-15 | 1968-11-20 | Parke Davis & Co | New organic amines and methods for their production |
| US5019583A (en) | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
| US5466700A (en) | 1993-08-30 | 1995-11-14 | Glaxo Wellcome Inc. | Anesthetic use of N-phenyl-N-(4-piperidinyl)amides |
| US5866591A (en) | 1996-09-11 | 1999-02-02 | Glaxo Wellcome Inc. | Stable formulations of remifentanil |
| US20040254182A1 (en) * | 2000-01-28 | 2004-12-16 | Mulvihill Mark Joseph | Enhanced propertied pharmaceuticals |
| US20040248963A1 (en) | 2001-11-23 | 2004-12-09 | Bueno Melendo Ana Belen | Prodrugs of excitatory amino acids |
| DE60335428D1 (de) | 2002-01-31 | 2011-02-03 | Randox Lab Ltd | Immunogene, Antikörper und Konjugate für Ketamin und dessen Metaboliten |
| NZ540282A (en) * | 2002-11-18 | 2008-06-30 | Yaupon Therapeutics Inc | Analgesic uses of norketamine and ketamine/norketamine prodrugs |
| CA2620374C (en) * | 2005-09-28 | 2012-12-11 | Thomas Meyer | Pharmaceutical compositions for the treatment of inner ear disorders |
| WO2008134525A1 (en) | 2007-04-26 | 2008-11-06 | Auspex Pharmaeuticals, Inc. | Deuterium labelled ketamine |
| AU2012323845B9 (en) * | 2011-10-14 | 2017-06-29 | Sri International | The use of (2R, 6R)-hydroxynorketamine, (S)-dehydronorketamine and other stereoisomeric dehydro and hydroxylated metabolites of (R,S)- ketamine in the treatment of depression and neuropathic pain |
| HK1212673A1 (zh) * | 2012-10-08 | 2016-06-17 | 奥克兰服务有限公司 | 氯胺酮衍生物 |
-
2013
- 2013-10-08 HK HK16100661.0A patent/HK1212673A1/zh unknown
- 2013-10-08 KR KR1020157012009A patent/KR20150065873A/ko not_active Ceased
- 2013-10-08 US US14/433,957 patent/US20150259277A1/en not_active Abandoned
- 2013-10-08 AU AU2013328280A patent/AU2013328280B2/en not_active Ceased
- 2013-10-08 EP EP13846133.0A patent/EP2903963A4/en not_active Withdrawn
- 2013-10-08 BR BR112015007647A patent/BR112015007647A2/pt not_active Application Discontinuation
- 2013-10-08 CN CN201380061537.2A patent/CN104837810B/zh not_active Expired - Fee Related
- 2013-10-08 MX MX2015004362A patent/MX2015004362A/es unknown
- 2013-10-08 IN IN3854DEN2015 patent/IN2015DN03854A/en unknown
- 2013-10-08 WO PCT/IB2013/059191 patent/WO2014057414A1/en not_active Ceased
- 2013-10-08 CA CA2922340A patent/CA2922340A1/en not_active Abandoned
- 2013-10-08 EA EA201590697A patent/EA201590697A1/ru unknown
- 2013-10-08 JP JP2015535162A patent/JP6309957B2/ja not_active Expired - Fee Related
-
2017
- 2017-03-20 US US15/463,532 patent/US10239825B2/en not_active Expired - Fee Related
-
2018
- 2018-03-14 JP JP2018046540A patent/JP2018127466A/ja active Pending
-
2019
- 2019-02-06 US US16/269,015 patent/US20190169113A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA201590697A1 (ru) | 2015-09-30 |
| AU2013328280B2 (en) | 2017-12-21 |
| JP2018127466A (ja) | 2018-08-16 |
| EP2903963A1 (en) | 2015-08-12 |
| BR112015007647A2 (pt) | 2017-07-04 |
| WO2014057414A9 (en) | 2014-12-18 |
| US20190169113A1 (en) | 2019-06-06 |
| IN2015DN03854A (OSRAM) | 2015-10-02 |
| HK1212673A1 (zh) | 2016-06-17 |
| KR20150065873A (ko) | 2015-06-15 |
| WO2014057414A1 (en) | 2014-04-17 |
| JP6309957B2 (ja) | 2018-04-11 |
| US20170190653A1 (en) | 2017-07-06 |
| CN104837810B (zh) | 2019-08-06 |
| US20150259277A1 (en) | 2015-09-17 |
| CA2922340A1 (en) | 2014-04-17 |
| CN104837810A (zh) | 2015-08-12 |
| JP2015535847A (ja) | 2015-12-17 |
| AU2013328280A1 (en) | 2015-05-14 |
| US10239825B2 (en) | 2019-03-26 |
| EP2903963A4 (en) | 2016-05-25 |
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