IN2015DN02296A - - Google Patents

Info

Publication number
IN2015DN02296A
IN2015DN02296A IN2296DEN2015A IN2015DN02296A IN 2015DN02296 A IN2015DN02296 A IN 2015DN02296A IN 2296DEN2015 A IN2296DEN2015 A IN 2296DEN2015A IN 2015DN02296 A IN2015DN02296 A IN 2015DN02296A
Authority
IN
India
Prior art keywords
preparation
formula
present
eslicarbazepine acetate
provides
Prior art date
Application number
Other languages
English (en)
Inventor
Ketan; Hirpara
Kdv; Jesunadh
Mukesh Kumar; Sharma
Chandra Has; Khanduri
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Priority to IN2296DEN2015 priority Critical patent/IN2015DN02296A/en
Publication of IN2015DN02296A publication Critical patent/IN2015DN02296A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
IN2296DEN2015 2012-09-26 2013-09-26 IN2015DN02296A (hu)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN2296DEN2015 IN2015DN02296A (hu) 2012-09-26 2013-09-26

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3003DE2012 2012-09-26
IN2296DEN2015 IN2015DN02296A (hu) 2012-09-26 2013-09-26
PCT/IB2013/058892 WO2014049550A1 (en) 2012-09-26 2013-09-26 Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate

Publications (1)

Publication Number Publication Date
IN2015DN02296A true IN2015DN02296A (hu) 2015-08-21

Family

ID=49765586

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2296DEN2015 IN2015DN02296A (hu) 2012-09-26 2013-09-26

Country Status (4)

Country Link
US (1) US20150232426A1 (hu)
EP (1) EP2900640A1 (hu)
IN (1) IN2015DN02296A (hu)
WO (1) WO2014049550A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105130899A (zh) * 2015-08-25 2015-12-09 安徽省新星药物开发有限责任公司 一种醋酸艾司利卡西平的合成方法
CN108101844A (zh) * 2018-03-14 2018-06-01 常州沃腾化工科技有限公司 10,11-二氢-10氧代-5H-二苯并[b,f]氮杂*-5-甲酰胺的制备方法
CN111423307A (zh) * 2020-05-19 2020-07-17 上海卫希医药科技有限公司 一种2，2，4，4-四甲基环丁二酮还原方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
IT1272897B (it) 1995-01-13 1997-07-01 I F C Iniziative Finanziaarie Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PT101732B (pt) 1995-06-30 1997-12-31 Portela & Ca Sa Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
AT408224B (de) 1999-03-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von oxcarbazepin
GB0002740D0 (en) 2000-02-07 2000-03-29 Novartis Ag Organic compounds
GB0111566D0 (en) 2001-05-11 2001-07-04 Portela & Ca Sa Method for preparation of (s)-(+)-and (r)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azephine-5-carboxamide
GB0112812D0 (en) 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
US6670472B2 (en) 2001-10-09 2003-12-30 Max India Limited Process for the preparation of 10-methoxycarbamazepine
IL165694A0 (en) 2002-06-14 2006-01-15 Taro Pharmaceuticals Usa Inc Method of preparing a 5h-dibenzÄb,fÜazepine-5-carboxamide
GB0223224D0 (en) 2002-10-07 2002-11-13 Novartis Ag Organic compounds
WO2005066133A2 (en) 2003-10-20 2005-07-21 Amoli Organics Ltd. NOVEL PROCESS FOR PREPARATION OF 10-OXO-10, 11-DIHYDRO-5H-DIBENZ [b,f]AZEPINE-5-CARBOXAMIDE (OXCARBAZEPINE) VIA INTERMEDIATE, 10-METHOXY-5H-DIBENZ[b,f] AZEPINE-5-CARBONYLCHLORIDE
ITMI20040452A1 (it) 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
WO2005096709A2 (en) 2004-03-11 2005-10-20 Sun Pharmaceutical Industries Limited A process for the preparation of 10,11-dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide
US7459553B2 (en) 2004-03-11 2008-12-02 Glenmark Generics Ltd. Process for the preparation of carboxamide compounds
EP1600443A1 (en) 2004-05-26 2005-11-30 Alberto Milanese Process for the preparation of oxcarbazepine
CA2471666C (en) 2004-06-18 2009-10-13 Apotex Pharmachem Inc. An improved process for the preparation of oxcarbazepine and related intermediates
GB2416167A (en) 2004-07-13 2006-01-18 Portela & Ca Sa Chiral inversion and esterification of (S)- and (R)-10-hydroxy-dibenzazepine carboxamides
ITMI20042291A1 (it) 2004-11-26 2005-02-26 Farchema S R L Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
GB2422149A (en) 2005-01-14 2006-07-19 Portela & Ca Sa Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
GB0515690D0 (en) 2005-07-29 2005-09-07 Portela & Ca Sa Asymmetric catalytic reduction
GB2437078A (en) 2006-04-11 2007-10-17 Portela & Ca Sa 10-Acyloxy-5H-dibenzo[b,f]azepine-5-carboxamides & their asymmetric hydrogenation to the chiral 10,11-dihydro derivatives
WO2007141798A1 (en) 2006-06-07 2007-12-13 Jubilant Organosys Limited Process for producing oxcarbazepine via an 11-alkoxy-10-halo-dihydroiminostilbene intermediate
WO2008012837A1 (en) 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-l10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
US8530647B2 (en) 2008-05-08 2013-09-10 Mylan Laboratories Limited Process for the preparation of oxcarbazepine
CN100591672C (zh) 2008-07-04 2010-02-24 浙江工业大学 一种奥卡西平的化学合成方法
WO2010113179A2 (en) 2009-04-02 2010-10-07 Glenmark Generics Limited A process for the purification of eslicarbazepine acetate
WO2011091131A2 (en) 2010-01-23 2011-07-28 Dr. Reddy's Laboratories Ltd. Eslicarbazepine acetate and its polymorphs
EP2383261B1 (en) 2010-04-23 2013-09-04 Euticals GmbH Process for the asymmetric hydrogenation of ketones

Also Published As

Publication number Publication date
EP2900640A1 (en) 2015-08-05
WO2014049550A1 (en) 2014-04-03
US20150232426A1 (en) 2015-08-20

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