IN2014DN10758A - - Google Patents

Info

Publication number
IN2014DN10758A
IN2014DN10758A IN10758DEN2014A IN2014DN10758A IN 2014DN10758 A IN2014DN10758 A IN 2014DN10758A IN 10758DEN2014 A IN10758DEN2014 A IN 10758DEN2014A IN 2014DN10758 A IN2014DN10758 A IN 2014DN10758A
Authority
IN
India
Prior art keywords
group
alkyl group
epoxyketone
substituent
producing
Prior art date
Application number
Other languages
English (en)
Inventor
Yukihiro Nishino
Kazuya Wakui
Shota Murase
Yoshifumi Sakai
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of IN2014DN10758A publication Critical patent/IN2014DN10758A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
    • C07D301/19—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic hydroperoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
IN10758DEN2014 2012-06-29 2013-06-27 IN2014DN10758A (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2012146821 2012-06-29
US201261735196P 2012-12-10 2012-12-10
JP2013026801 2013-02-14
US201361789996P 2013-03-15 2013-03-15
PCT/JP2013/068308 WO2014003203A2 (fr) 2012-06-29 2013-06-27 Procédé de production d'un composé époxycétone stéréosélectif

Publications (1)

Publication Number Publication Date
IN2014DN10758A true IN2014DN10758A (fr) 2015-09-04

Family

ID=49783967

Family Applications (1)

Application Number Title Priority Date Filing Date
IN10758DEN2014 IN2014DN10758A (fr) 2012-06-29 2013-06-27

Country Status (6)

Country Link
US (1) US9187442B2 (fr)
EP (1) EP2867202B1 (fr)
JP (1) JP6176259B2 (fr)
CN (1) CN104411682B (fr)
IN (1) IN2014DN10758A (fr)
WO (1) WO2014003203A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104230857A (zh) * 2014-08-19 2014-12-24 上海皓元生物医药科技有限公司 卡非佐米(Carfilzomib)的中间体化合物的制备方法及其中间体化合物
EP3297678B1 (fr) 2015-05-21 2021-07-07 Laurus Labs Limited Procédé perfectionné de préparation de carfilzomib ou de sels pharmaceutiquement acceptables de celui-ci
CN105017181B (zh) * 2015-07-02 2017-10-10 南京师范大学 卡非佐米关键中间体及其衍生物的制备方法
CN105622458A (zh) * 2015-12-22 2016-06-01 中国药科大学 (s)-4-氨基-2-甲基-5-苯基戊-1-烯-3-酮的制备方法
KR102524751B1 (ko) 2016-06-29 2023-04-21 케자르 라이프 사이언스 펩티드 에폭시케톤 면역프로테아제 저해제 및 그 전구체의 제조 방법
LT3478670T (lt) 2016-06-29 2023-05-25 Kezar Life Sciences Kristalinės peptidų epoksiketono imunoproteasomų inhibitoriaus druskos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050256324A1 (en) 2004-05-10 2005-11-17 Proteolix, Inc. Synthesis of amino acid keto-epoxides
SI2030981T1 (sl) * 2004-05-10 2014-11-28 Onyx Therapeutics, Inc. Spojine za inhibiranje proteasomskega encima
CA2566839A1 (fr) * 2004-05-17 2005-11-24 Proteolix, Inc. Synthese de ceto-epoxydes d'acides amines
JP4809229B2 (ja) 2004-06-25 2011-11-09 国立大学法人東北大学 アルコール酸化触媒およびその合成方法
AU2007261345B2 (en) 2006-06-19 2012-02-23 Onyx Therapeutics, Inc. Peptide epoxyketones for proteasome inhibition
JP4803074B2 (ja) 2007-03-06 2011-10-26 日産化学工業株式会社 アルコール酸化触媒およびその合成方法
US8013189B2 (en) * 2007-09-21 2011-09-06 Basf Se Accelerated amide and ester reductions with amine boranes and additives
KR20170125413A (ko) 2007-10-04 2017-11-14 오닉스 세라퓨틱스, 인크. 결정형 펩티드 에폭시 케톤 프로테아제 저해제 및 아미노산 케토-에폭시드의 합성
US7902376B2 (en) * 2008-01-23 2011-03-08 Merck Sharp & Dohme Corp. Process for preparing chiral dipeptidyl peptidase-IV inhibitor intermediates
WO2009145323A1 (fr) 2008-05-30 2009-12-03 日産化学工業株式会社 Procédé d'oxydation d'un alcool à l'aide d'un composé polycyclique

Also Published As

Publication number Publication date
JP6176259B2 (ja) 2017-08-09
US20150126755A1 (en) 2015-05-07
WO2014003203A3 (fr) 2014-03-20
WO2014003203A2 (fr) 2014-01-03
EP2867202B1 (fr) 2017-08-09
EP2867202A2 (fr) 2015-05-06
CN104411682A (zh) 2015-03-11
CN104411682B (zh) 2016-11-16
US9187442B2 (en) 2015-11-17
JP2015526384A (ja) 2015-09-10

Similar Documents

Publication Publication Date Title
MX2018016267A (es) Metodo para producir derivado de piridona policiclica sustituida y cristal del mismo.
IN2014DN10758A (fr)
IN2012DN02751A (fr)
NZ745013A (en) Process for preparing bile acid derivatives
MX2013006926A (es) Compuestos y composiciones fotocromicas.
PH12014502866A1 (en) Fungicidal heterocyclic carboxamides
MX358463B (es) Pirano[3,2-d][1,3]tiazol como inhibidores de glicosidasa.
BR112012011689A2 (pt) processo para a produção de etexilato de dabigatran
EP2412700A4 (fr) Méthode de production d'un dérivé d'acide gamma-aminé bicyclique
PH12015501226A1 (en) Crystalline 6,7-unsaturated-7-carbamoyl morphinane derivative, and method for producing the same
IN2012DN01815A (fr)
NZ586187A (en) Processes for the synthesis of sinomenine derivatives and their intermediate
MX2014005870A (es) Proceso para preparar compuestos de 1h -pirazol - 5 - carboxilato n - sustituidos y derivados de los mismos.
MY150280A (en) Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid
IN2014DN00144A (fr)
IN2015DN02424A (fr)
IN2014MN00976A (fr)
MX342273B (es) Proceso para la preparacion de esteres de acido (5-fluoro-2-metil-3-quinolina-2-ilmetil-indol-1-il)-acetico.
NZ709362A (en) Process for the preparation of 1-([1,3]dioxolan-4-ylmethyl)-1h-pyrazol-3-ylamine
UA111950C2 (uk) Гетероциклічні сполуки для лікування або профілактики розладів, викликаних зниженою нейротрансмісією серотоніну, норепінефрину або допаміну
PH12016501704B1 (en) Method for producing 2-acyliminopyridine derivative
IN2015DN02854A (fr)
MX2010001961A (es) Procedimiento para la preparacion de derivados de 2,2-difluoroetilamina mediante hidrogenacion de amida.
TW201613856A (en) Method for producing harmful-organism control agent, and intermediate thereof
MX355654B (es) Derivado de paroxetina.