IN2014DN10669A - - Google Patents

Info

Publication number
IN2014DN10669A
IN2014DN10669A IN10669DEN2014A IN2014DN10669A IN 2014DN10669 A IN2014DN10669 A IN 2014DN10669A IN 10669DEN2014 A IN10669DEN2014 A IN 10669DEN2014A IN 2014DN10669 A IN2014DN10669 A IN 2014DN10669A
Authority
IN
India
Prior art keywords
compound
formula
pharmaceutically acceptable
acceptable salt
salt
Prior art date
Application number
Other languages
English (en)
Inventor
Edward Savory
Martyn Pritchard
Mike Ashwood
Original Assignee
Proximagen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1211788.3A external-priority patent/GB201211788D0/en
Priority claimed from GBGB1304812.9A external-priority patent/GB201304812D0/en
Application filed by Proximagen Ltd filed Critical Proximagen Ltd
Publication of IN2014DN10669A publication Critical patent/IN2014DN10669A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN10669DEN2014 2012-07-03 2013-07-03 IN2014DN10669A (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1211788.3A GB201211788D0 (en) 2012-07-03 2012-07-03 Pro-drug compounds
GBGB1304812.9A GB201304812D0 (en) 2013-03-15 2013-03-15 Pro-drug compounds
PCT/GB2013/051767 WO2014006407A1 (en) 2012-07-03 2013-07-03 Pro-drug compounds

Publications (1)

Publication Number Publication Date
IN2014DN10669A true IN2014DN10669A (uk) 2015-08-28

Family

ID=48782540

Family Applications (1)

Application Number Title Priority Date Filing Date
IN10669DEN2014 IN2014DN10669A (uk) 2012-07-03 2013-07-03

Country Status (7)

Country Link
US (2) US9499510B2 (uk)
EP (1) EP2870148A1 (uk)
AU (1) AU2013285164A1 (uk)
CA (1) CA2877578A1 (uk)
IN (1) IN2014DN10669A (uk)
WO (1) WO2014006407A1 (uk)
ZA (1) ZA201409213B (uk)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013285164A1 (en) 2012-07-03 2015-01-22 Proximagen Limited Pro-drug compounds
GB201304814D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Pro-drug compounds
GB201322932D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Pro-drug compounds
GB201322934D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Prodrug compounds
CA2958879A1 (en) 2014-08-22 2016-02-25 Auckland Uniservices Limited Channel modulators
US11717506B2 (en) * 2019-05-07 2023-08-08 The Johns Hopkins University Neuroprotective compounds for amyotrophic lateral sclerosis

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126311B1 (en) 1983-05-18 1989-09-13 Beecham Group Plc Benzopyran derivatives.
DE3475786D1 (de) 1983-09-01 1989-02-02 Beecham Group Plc Chromanol derivatives
EP0301713A3 (en) 1987-07-07 1990-05-02 Beecham Group Plc Chroman derivatives for treatment of pulmonary hypertension
KR100326968B1 (ko) 1992-12-11 2002-07-27 스미스클라인비이참피이엘시이 약학적 활성을 가진 이환식 화합물
ES2143541T3 (es) 1992-12-11 2000-05-16 Smithkline Beecham Plc Composicion farmaceutica que contiene compuestos de tipo biciclico.
ATE263770T1 (de) 1994-02-04 2004-04-15 Smithkline Beecham Plc Verfahren zum epoxidieren prochiral olefine
GB9411635D0 (en) * 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
CZ286081B6 (cs) 1994-06-10 2000-01-12 Smithkline Beecham P. L. C. Benzopyrany a jejich použití jako terapeutických činidel
GB9813949D0 (en) 1998-06-29 1998-08-26 Smithkline Beecham Plc Novel compounds
CA2586410A1 (en) 2004-12-23 2006-07-06 Xenoport, Inc. Serine amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof
MX2010013312A (es) 2008-06-05 2011-05-30 Minster Res Ltd Tratamientos novedoos.
CA2726878A1 (en) 2008-06-05 2009-12-10 Minster Research Limited Novel treatments
CN102770134A (zh) 2009-12-03 2012-11-07 普罗克西梅根有限公司 传染性失调的治疗
CA2782625A1 (en) 2009-12-03 2011-06-09 Proximagen Ltd Treatment of allodynia and hyperalgesia
AU2013285164A1 (en) 2012-07-03 2015-01-22 Proximagen Limited Pro-drug compounds
GB201304814D0 (en) 2013-03-15 2013-05-01 Proximagen Ltd Pro-drug compounds

Also Published As

Publication number Publication date
CA2877578A1 (en) 2014-01-09
AU2013285164A1 (en) 2015-01-22
US20140011773A1 (en) 2014-01-09
US20150322034A1 (en) 2015-11-12
WO2014006407A1 (en) 2014-01-09
US9499510B2 (en) 2016-11-22
ZA201409213B (en) 2016-07-27
EP2870148A1 (en) 2015-05-13

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