IN2014DN08487A - - Google Patents
Info
- Publication number
- IN2014DN08487A IN2014DN08487A IN8487DEN2014A IN2014DN08487A IN 2014DN08487 A IN2014DN08487 A IN 2014DN08487A IN 8487DEN2014 A IN8487DEN2014 A IN 8487DEN2014A IN 2014DN08487 A IN2014DN08487 A IN 2014DN08487A
- Authority
- IN
- India
- Prior art keywords
- methods
- conjugates
- subject
- disclosed
- imaging
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 5
- 238000003384 imaging method Methods 0.000 abstract 2
- BQHFYSWNHZMMDO-WDSKDSINSA-N (2r)-2-[2-[[(1r)-1-carboxy-2-sulfanylethyl]amino]ethylamino]-3-sulfanylpropanoic acid Chemical compound OC(=O)[C@H](CS)NCCN[C@@H](CS)C(O)=O BQHFYSWNHZMMDO-WDSKDSINSA-N 0.000 abstract 1
- DZLNHFMRPBPULJ-VKHMYHEASA-N L-thioproline Chemical compound OC(=O)[C@@H]1CSCN1 DZLNHFMRPBPULJ-VKHMYHEASA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261615684P | 2012-03-26 | 2012-03-26 | |
| PCT/US2013/033919 WO2013148710A1 (en) | 2012-03-26 | 2013-03-26 | Efficient synthesis of ethylenedicysteine-sugar conjugates for imaging and therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN08487A true IN2014DN08487A (enrdf_load_html_response) | 2015-05-08 |
Family
ID=49261180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN8487DEN2014 IN2014DN08487A (enrdf_load_html_response) | 2012-03-26 | 2013-03-26 |
Country Status (20)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107955053B (zh) * | 2017-12-11 | 2019-10-29 | 江西宇能制药有限公司 | 一种左炔诺孕酮中间体乙基锂氨物的制备方法 |
| WO2023077375A1 (en) * | 2021-11-04 | 2023-05-11 | Shenzhen Xpectvision Technology Co., Ltd. | In vivo xrf agent |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4925650A (en) * | 1988-11-16 | 1990-05-15 | Mallinckrodt, Inc. | Technetium -99m complex for examining the renal function |
| US6407071B1 (en) * | 1998-06-04 | 2002-06-18 | Co-Enzyme Technology Ltd. | Method and composition for treating malignant cells |
| US6692724B1 (en) * | 1999-10-25 | 2004-02-17 | Board Of Regents, The University Of Texas System | Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging |
| US7067111B1 (en) | 1999-10-25 | 2006-06-27 | Board Of Regents, University Of Texas System | Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging |
| IL153218A0 (en) * | 2000-06-02 | 2003-07-06 | Univ Texas | Ethylenedicysteine (ec) -drug conjugates |
| CN101985443A (zh) * | 2002-11-07 | 2011-03-16 | 得克萨斯大学体系董事会 | 乙二半胱氨酸（ec）-药物结合物、组合物及用于组织特异性疾病显像的方法 |
| BRPI0606395A2 (pt) * | 2005-01-05 | 2009-06-23 | Univ Texas | conjugados para ambas imagem e radioquimioterapia: composição, fabricação e aplicações |
| WO2008036067A2 (en) * | 2005-07-19 | 2008-03-27 | The University Of Tennessee Research Foundation | Thiazolidinone amides, thiazolidine carboxylic acid amides, and serine amides, including polyamine conjugates thereof, as selective anti-cancer agents |
| US10925977B2 (en) * | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
| US20080107198A1 (en) | 2006-11-07 | 2008-05-08 | Innovative Sonic Limited | Method and apparatus for performing multi-input multi-output transmission in a wireless communications system |
| CN102159253A (zh) | 2008-03-24 | 2011-08-17 | 得克萨斯大学体系董事会 | 心肌病的显像引导的治疗:组合物、制备和用途 |
-
2013
- 2013-03-26 ES ES13767943T patent/ES2782504T3/es active Active
- 2013-03-26 SI SI201331704T patent/SI2830666T1/sl unknown
- 2013-03-26 BR BR112014023988-6A patent/BR112014023988B1/pt active IP Right Grant
- 2013-03-26 WO PCT/US2013/033919 patent/WO2013148710A1/en active Application Filing
- 2013-03-26 HU HUE13767943A patent/HUE048557T2/hu unknown
- 2013-03-26 KR KR1020147030004A patent/KR102040476B1/ko active Active
- 2013-03-26 US US13/850,917 patent/US9549995B2/en active Active
- 2013-03-26 EP EP13767943.7A patent/EP2830666B1/en active Active
- 2013-03-26 RU RU2014143024A patent/RU2674673C2/ru active
- 2013-03-26 CN CN201380021343.XA patent/CN104321083B/zh active Active
- 2013-03-26 AU AU2013239870A patent/AU2013239870B2/en active Active
- 2013-03-26 PL PL13767943T patent/PL2830666T3/pl unknown
- 2013-03-26 PT PT137679437T patent/PT2830666T/pt unknown
- 2013-03-26 DK DK13767943.7T patent/DK2830666T3/da active
- 2013-03-26 CA CA2868857A patent/CA2868857C/en active Active
- 2013-03-26 IN IN8487DEN2014 patent/IN2014DN08487A/en unknown
- 2013-03-26 JP JP2015503472A patent/JP6336695B2/ja active Active
- 2013-03-26 RS RS20200382A patent/RS60085B1/sr unknown
-
2014
- 2014-09-28 IL IL234858A patent/IL234858A/en active IP Right Grant
- 2014-10-06 ZA ZA2014/07213A patent/ZA201407213B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2674673C2 (ru) | 2018-12-12 |
| HUE048557T2 (hu) | 2020-07-28 |
| PL2830666T3 (pl) | 2021-03-08 |
| IL234858A (en) | 2017-03-30 |
| ES2782504T3 (es) | 2020-09-15 |
| KR102040476B1 (ko) | 2019-11-06 |
| RS60085B1 (sr) | 2020-05-29 |
| BR112014023988B1 (pt) | 2021-02-02 |
| US9549995B2 (en) | 2017-01-24 |
| AU2013239870A1 (en) | 2014-10-23 |
| WO2013148710A1 (en) | 2013-10-03 |
| SI2830666T1 (sl) | 2020-07-31 |
| CA2868857A1 (en) | 2013-10-03 |
| US20130343995A1 (en) | 2013-12-26 |
| CN104321083B (zh) | 2017-11-10 |
| EP2830666A1 (en) | 2015-02-04 |
| PT2830666T (pt) | 2020-04-02 |
| DK2830666T3 (da) | 2020-04-06 |
| AU2013239870B2 (en) | 2017-07-20 |
| EP2830666B1 (en) | 2020-01-08 |
| JP2015512408A (ja) | 2015-04-27 |
| CN104321083A (zh) | 2015-01-28 |
| KR20140144720A (ko) | 2014-12-19 |
| JP6336695B2 (ja) | 2018-06-06 |
| EP2830666A4 (en) | 2015-11-04 |
| RU2014143024A (ru) | 2016-05-20 |
| ZA201407213B (en) | 2017-08-30 |
| CA2868857C (en) | 2020-06-02 |
| HK1204567A1 (en) | 2015-11-27 |
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