IN2014DN07982A - - Google Patents
Info
- Publication number
- IN2014DN07982A IN2014DN07982A IN7982DEN2014A IN2014DN07982A IN 2014DN07982 A IN2014DN07982 A IN 2014DN07982A IN 7982DEN2014 A IN7982DEN2014 A IN 7982DEN2014A IN 2014DN07982 A IN2014DN07982 A IN 2014DN07982A
- Authority
- IN
- India
- Prior art keywords
- preparation
- medetomidine
- aceton
- propanal
- perfumes
- Prior art date
Links
- WLPXNBYWDDYJTN-UHFFFAOYSA-N 1-bromo-2,3-dimethylbenzene Chemical compound CC1=CC=CC(Br)=C1C WLPXNBYWDDYJTN-UHFFFAOYSA-N 0.000 abstract 1
- GNEYVIZQCGXVEV-UHFFFAOYSA-N 2-(2,3-dimethylphenyl)propanal Chemical compound O=CC(C)C1=CC=CC(C)=C1C GNEYVIZQCGXVEV-UHFFFAOYSA-N 0.000 abstract 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 1
- HRLIOXLXPOHXTA-UHFFFAOYSA-N medetomidine Chemical compound C=1C=CC(C)=C(C)C=1C(C)C1=CN=C[N]1 HRLIOXLXPOHXTA-UHFFFAOYSA-N 0.000 abstract 1
- 229960002140 medetomidine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002304 perfume Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
- C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
- C07C1/22—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms by reduction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
- C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
- C07C1/24—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms by elimination of water
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/86—Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/228—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
- C07D301/12—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with hydrogen peroxide or inorganic peroxides or peracids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/24—Synthesis of the oxirane ring by splitting off HAL—Y from compounds containing the radical HAL—C—C—OY
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/0061—Essential oils; Perfumes compounds containing a six-membered aromatic ring not condensed with another ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2531/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- C07C2531/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
- C07C2531/025—Sulfonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261644198P | 2012-05-08 | 2012-05-08 | |
| EP12167135 | 2012-05-08 | ||
| EP12187354 | 2012-10-05 | ||
| PCT/EP2012/070873 WO2012172120A2 (en) | 2012-05-08 | 2012-10-22 | 2-(2,3-dimethylphenyl)-1-propanal and its use as perfume |
| EP12192621 | 2012-11-14 | ||
| PCT/EP2012/072797 WO2013011156A2 (en) | 2012-05-08 | 2012-11-15 | Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN07982A true IN2014DN07982A (de) | 2015-05-01 |
Family
ID=47558544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN7982DEN2014 IN2014DN07982A (de) | 2012-05-08 | 2012-11-15 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9126915B2 (de) |
| EP (1) | EP2847157B1 (de) |
| JP (1) | JP5777840B2 (de) |
| KR (1) | KR101537204B1 (de) |
| CN (1) | CN104203893B (de) |
| AU (1) | AU2012285676B2 (de) |
| CA (1) | CA2866431C (de) |
| CL (2) | CL2014002908A1 (de) |
| CY (1) | CY1117404T1 (de) |
| DK (1) | DK2847157T3 (de) |
| EA (2) | EA025591B1 (de) |
| ES (1) | ES2557638T3 (de) |
| HR (1) | HRP20151390T1 (de) |
| HU (1) | HUE026686T2 (de) |
| IN (1) | IN2014DN07982A (de) |
| MY (1) | MY165212A (de) |
| PL (1) | PL2847157T3 (de) |
| PT (1) | PT2847157E (de) |
| SG (1) | SG11201405611SA (de) |
| TW (1) | TWI531557B (de) |
| WO (1) | WO2013011156A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2014DN07982A (de) * | 2012-05-08 | 2015-05-01 | Lonza Ag | |
| HRP20160215T1 (hr) * | 2012-05-08 | 2016-03-25 | Lonza Ag | Postupak za pripravu medetomidina |
| JP5777841B2 (ja) | 2012-06-28 | 2015-09-09 | ロンザ・リミテッド | クロロアセトンを用いてメデトミジンを調製するための方法 |
| JP5779298B2 (ja) | 2012-06-28 | 2015-09-16 | ロンザ・リミテッド | クロロアセトンを用いて２−（２，３−ジメチルフェニル）−１−プロパナールを調製するための方法 |
| WO2016074118A1 (en) * | 2014-11-10 | 2016-05-19 | Givaudan Sa | Improvements in or relating to organic compounds |
| GB201501593D0 (en) * | 2015-01-30 | 2015-03-18 | Cambrex Karlskoga Ab | New compounds and processes |
| WO2022139117A1 (ko) * | 2020-12-21 | 2022-06-30 | 주식회사 엘지화학 | 알파-메틸스타이렌의 제조방법 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790604A (fr) | 1971-10-28 | 1973-04-26 | Sandoz Sa | Nouveaux aminoalcanols, leur preparation et leur application comme medicaments |
| DE2340812C2 (de) * | 1973-08-11 | 1982-05-27 | Basf Ag, 6700 Ludwigshafen | Phenylpropanale sowie ein Verfahren zu deren Herstellung |
| JPS51100041A (en) | 1975-02-26 | 1976-09-03 | Kanebo Ltd | 22 * 44 isobuchirufueniru * puropionsanno seizoho |
| JPS51100042A (en) | 1975-02-26 | 1976-09-03 | Kanebo Ltd | 22 * 44 isobuchirufueniru * puropionsanno seizoho |
| GB2092569B (en) | 1981-02-05 | 1984-09-19 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
| GB2101114B (en) | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
| ATE78722T1 (de) | 1984-02-24 | 1992-08-15 | Sagami Chem Res | Methode zum isomerisieren eines glycidats. |
| JPS62103037A (ja) * | 1985-10-29 | 1987-05-13 | Hamari Yakuhin Kogyo Kk | ２−（４−イソブチルフエニル）−プロピオンアルデヒドの製造法 |
| DE19714042A1 (de) | 1997-04-05 | 1998-10-08 | Henkel Kgaa | Verfahren zur Herstellung aromatischer Aldehyde |
| SE513474C2 (sv) | 1999-01-25 | 2000-09-18 | Hans Elwing Instutionen Foer C | Metod för att förhindra kräftdjurs, särskilt havstulpaners, etablering på fasta ytor med hjälp av en substans som stör nervsignaler, varvid substansen är medetomidin, dvs (+)-4-/1- (2,3-dimetylfenyl)-etyl/-IH-imidazol |
| EP1918282A1 (de) * | 2006-11-06 | 2008-05-07 | "Joint Stock Company Grindeks" | Verfahren zur Herstellung von Medetomidine und ihre Salzen |
| GB2453982B (en) | 2007-10-24 | 2009-09-16 | Norbrook Lab Ltd | Chemical process for the preparation of Medetomidine |
| US7902247B2 (en) | 2008-01-09 | 2011-03-08 | Allergan, Inc. | Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors |
| CN102753532B (zh) * | 2009-12-09 | 2015-05-13 | I-技术有限公司 | 美托咪定的制备方法 |
| IN2014DN07982A (de) * | 2012-05-08 | 2015-05-01 | Lonza Ag | |
| HRP20160215T1 (hr) * | 2012-05-08 | 2016-03-25 | Lonza Ag | Postupak za pripravu medetomidina |
| WO2012172119A2 (en) * | 2012-05-08 | 2012-12-20 | Lonza Ltd | Method for the preparation of medetomidine |
| WO2012172120A2 (en) * | 2012-05-08 | 2012-12-20 | Lonza Ltd | 2-(2,3-dimethylphenyl)-1-propanal and its use as perfume |
| WO2012172122A2 (en) * | 2012-06-28 | 2012-12-20 | Lonza Ltd | Method for the preparation of 2-(2,3-dimethylphenyl)-1-propanal |
| WO2012172121A1 (en) * | 2012-06-28 | 2012-12-20 | Lonza Ltd | Method for the preparation of medetomidine with chloroacetone |
| JP5777841B2 (ja) * | 2012-06-28 | 2015-09-09 | ロンザ・リミテッド | クロロアセトンを用いてメデトミジンを調製するための方法 |
| JP5779298B2 (ja) * | 2012-06-28 | 2015-09-16 | ロンザ・リミテッド | クロロアセトンを用いて２−（２，３−ジメチルフェニル）−１−プロパナールを調製するための方法 |
-
2012
- 2012-11-15 IN IN7982DEN2014 patent/IN2014DN07982A/en unknown
- 2012-11-15 KR KR1020147029913A patent/KR101537204B1/ko not_active Expired - Fee Related
- 2012-11-15 EA EA201400937A patent/EA025591B1/ru not_active IP Right Cessation
- 2012-11-15 MY MYPI2014002578A patent/MY165212A/en unknown
- 2012-11-15 EA EA201691508A patent/EA029130B1/ru not_active IP Right Cessation
- 2012-11-15 EP EP12784297.9A patent/EP2847157B1/de not_active Not-in-force
- 2012-11-15 US US14/386,020 patent/US9126915B2/en not_active Expired - Fee Related
- 2012-11-15 PL PL12784297T patent/PL2847157T3/pl unknown
- 2012-11-15 DK DK12784297.9T patent/DK2847157T3/en active
- 2012-11-15 CA CA2866431A patent/CA2866431C/en not_active Expired - Fee Related
- 2012-11-15 ES ES12784297.9T patent/ES2557638T3/es active Active
- 2012-11-15 HR HRP20151390TT patent/HRP20151390T1/hr unknown
- 2012-11-15 AU AU2012285676A patent/AU2012285676B2/en not_active Ceased
- 2012-11-15 JP JP2015510661A patent/JP5777840B2/ja not_active Expired - Fee Related
- 2012-11-15 HU HUE12784297A patent/HUE026686T2/en unknown
- 2012-11-15 WO PCT/EP2012/072797 patent/WO2013011156A2/en not_active Ceased
- 2012-11-15 CN CN201280072267.0A patent/CN104203893B/zh not_active Expired - Fee Related
- 2012-11-15 SG SG11201405611SA patent/SG11201405611SA/en unknown
- 2012-11-15 PT PT127842979T patent/PT2847157E/pt unknown
-
2013
- 2013-05-06 TW TW102116031A patent/TWI531557B/zh not_active IP Right Cessation
-
2014
- 2014-10-27 CL CL2014002908A patent/CL2014002908A1/es unknown
-
2015
- 2015-12-23 CY CY20151101185T patent/CY1117404T1/el unknown
-
2016
- 2016-06-29 CL CL2016001663A patent/CL2016001663A1/es unknown
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