IN2014DN07856A - 4-(3-BENZYLOXYPHENYLTHIO)-2-CHLORO-l-(3-NITROPROPYL)BENZENE CRYSTAL - Google Patents
4-(3-BENZYLOXYPHENYLTHIO)-2-CHLORO-l-(3-NITROPROPYL)BENZENE CRYSTALInfo
- Publication number
- IN2014DN07856A IN2014DN07856A IN7856DEN2014A IN2014DN07856A IN 2014DN07856 A IN2014DN07856 A IN 2014DN07856A IN 7856DEN2014 A IN7856DEN2014 A IN 7856DEN2014A IN 2014DN07856 A IN2014DN07856 A IN 2014DN07856A
- Authority
- IN
- India
- Prior art keywords
- benzyloxyphenylthio
- crystal
- compound
- nitropropyl
- chloro
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 4
- JCUWWTZYGLAQPG-UHFFFAOYSA-N 2-chloro-1-(3-nitropropyl)-4-(3-phenylmethoxyphenyl)sulfanylbenzene Chemical compound C1=C(Cl)C(CCC[N+](=O)[O-])=CC=C1SC1=CC=CC(OCC=2C=CC=CC=2)=C1 JCUWWTZYGLAQPG-UHFFFAOYSA-N 0.000 title abstract 2
- 229940125904 compound 1 Drugs 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 238000007670 refining Methods 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- RVYNIIJBIAINNT-UHFFFAOYSA-N propane-1,3-diol;hydrochloride Chemical compound Cl.OCCCO RVYNIIJBIAINNT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/26—Separation; Purification; Stabilisation; Use of additives
- C07C319/28—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012094758 | 2012-04-18 | ||
| PCT/JP2013/002585 WO2013157255A1 (ja) | 2012-04-18 | 2013-04-17 | 4-(3-ベンジルオキシフェニルチオ)-2-クロロ-1-(3-ニトロプロピル)ベンゼンの結晶 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN07856A true IN2014DN07856A (en) | 2015-04-24 |
Family
ID=49383225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN7856DEN2014 IN2014DN07856A (en) | 2012-04-18 | 2013-04-17 | 4-(3-BENZYLOXYPHENYLTHIO)-2-CHLORO-l-(3-NITROPROPYL)BENZENE CRYSTAL |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9315453B2 (de) |
| EP (1) | EP2840079B1 (de) |
| JP (1) | JP6062424B2 (de) |
| KR (1) | KR102025962B1 (de) |
| CN (1) | CN104379562B (de) |
| AU (1) | AU2013250625A1 (de) |
| CA (1) | CA2868252A1 (de) |
| ES (1) | ES2665312T3 (de) |
| IN (1) | IN2014DN07856A (de) |
| MX (1) | MX2014012435A (de) |
| RU (1) | RU2014146161A (de) |
| TW (1) | TWI554493B (de) |
| WO (1) | WO2013157255A1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2461212C (en) * | 2001-09-27 | 2010-08-17 | Kyorin Pharmaceutical Co., Ltd. | Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same |
| EP1806338B1 (de) * | 2004-10-12 | 2016-01-20 | Kyorin Pharmaceutical Co., Ltd. | Verfahren zur herstellung von 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorphenyl[ethyl]-1,3-propandiolhydrochlorid und hydraten davon, und zwischenprodukte in deren herstellung |
| CA2718987C (en) * | 2008-03-24 | 2016-03-08 | Kyorin Pharmaceutical Co., Ltd. | Method for crystallization of 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-ethyl]-1,3-propanediol hydrochloride |
-
2013
- 2013-04-17 WO PCT/JP2013/002585 patent/WO2013157255A1/ja not_active Ceased
- 2013-04-17 RU RU2014146161A patent/RU2014146161A/ru not_active Application Discontinuation
- 2013-04-17 IN IN7856DEN2014 patent/IN2014DN07856A/en unknown
- 2013-04-17 AU AU2013250625A patent/AU2013250625A1/en not_active Abandoned
- 2013-04-17 KR KR1020147028697A patent/KR102025962B1/ko not_active Expired - Fee Related
- 2013-04-17 CN CN201380020506.2A patent/CN104379562B/zh not_active Expired - Fee Related
- 2013-04-17 EP EP13778567.1A patent/EP2840079B1/de not_active Not-in-force
- 2013-04-17 ES ES13778567.1T patent/ES2665312T3/es active Active
- 2013-04-17 MX MX2014012435A patent/MX2014012435A/es unknown
- 2013-04-17 TW TW102113612A patent/TWI554493B/zh not_active IP Right Cessation
- 2013-04-17 CA CA2868252A patent/CA2868252A1/en not_active Abandoned
- 2013-04-17 JP JP2014511108A patent/JP6062424B2/ja not_active Expired - Fee Related
- 2013-04-17 US US14/385,854 patent/US9315453B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US9315453B2 (en) | 2016-04-19 |
| CN104379562A (zh) | 2015-02-25 |
| KR102025962B1 (ko) | 2019-09-26 |
| CA2868252A1 (en) | 2013-10-24 |
| CN104379562B (zh) | 2016-06-01 |
| AU2013250625A1 (en) | 2014-10-09 |
| TWI554493B (zh) | 2016-10-21 |
| RU2014146161A (ru) | 2016-06-10 |
| US20150073178A1 (en) | 2015-03-12 |
| EP2840079A4 (de) | 2015-11-18 |
| JPWO2013157255A1 (ja) | 2015-12-21 |
| EP2840079A1 (de) | 2015-02-25 |
| ES2665312T3 (es) | 2018-04-25 |
| EP2840079B1 (de) | 2018-02-21 |
| MX2014012435A (es) | 2014-12-10 |
| KR20150002665A (ko) | 2015-01-07 |
| WO2013157255A1 (ja) | 2013-10-24 |
| TW201348188A (zh) | 2013-12-01 |
| JP6062424B2 (ja) | 2017-01-18 |
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