IN2014DN05011A - - Google Patents

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Publication number
IN2014DN05011A
IN2014DN05011A IN5011DEN2014A IN2014DN05011A IN 2014DN05011 A IN2014DN05011 A IN 2014DN05011A IN 5011DEN2014 A IN5011DEN2014 A IN 5011DEN2014A IN 2014DN05011 A IN2014DN05011 A IN 2014DN05011A
Authority
IN
India
Prior art keywords
nmo
diagnosing
materials
methods
provides
Prior art date
Application number
Other languages
English (en)
Inventor
Vanda A Lennon
Thomas J Kryzer
Original Assignee
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation filed Critical Mayo Foundation
Publication of IN2014DN05011A publication Critical patent/IN2014DN05011A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/285Demyelinating diseases; Multipel sclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
IN5011DEN2014 2003-11-25 2004-11-24 IN2014DN05011A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/723,180 US7101679B2 (en) 2003-11-25 2003-11-25 Marker for neuromyelitis optica
PCT/US2004/039710 WO2005051178A2 (en) 2003-11-25 2004-11-24 Marker for neuromyelitis optica

Publications (1)

Publication Number Publication Date
IN2014DN05011A true IN2014DN05011A (enExample) 2015-07-10

Family

ID=34592190

Family Applications (1)

Application Number Title Priority Date Filing Date
IN5011DEN2014 IN2014DN05011A (enExample) 2003-11-25 2004-11-24

Country Status (9)

Country Link
US (5) US7101679B2 (enExample)
EP (1) EP1700120B1 (enExample)
JP (1) JP4538464B2 (enExample)
CN (1) CN1910456B (enExample)
AT (1) ATE424560T1 (enExample)
DE (1) DE602004019812D1 (enExample)
ES (1) ES2320006T3 (enExample)
IN (1) IN2014DN05011A (enExample)
WO (1) WO2005051178A2 (enExample)

Families Citing this family (31)

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US7101679B2 (en) 2003-11-25 2006-09-05 Mayo Foundation For Medical Education And Research Marker for neuromyelitis optica
US20070093673A1 (en) * 2005-10-24 2007-04-26 Andre Vachereau Boron-containing compounds, uses and preparation thereof
JP4273235B2 (ja) * 2006-06-01 2009-06-03 国立大学法人 新潟大学 アクアポリン4阻害薬
US8889102B2 (en) * 2007-09-20 2014-11-18 Mayo Foundation For Medical Education And Research Neuromyelitis optica autoantibodies as a marker for neoplasia
JP5117336B2 (ja) * 2008-09-18 2013-01-16 国立大学法人 千葉大学 多発性硬化症またはnmoの検査マーカーの測定方法
US9891219B2 (en) * 2008-10-10 2018-02-13 Mayo Foundation For Medical Education And Research Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive
GR1007341B (el) 2010-04-21 2011-07-05 ΕΛΛΗΝΙΚΟ ΙΝΣΤΙΤΟΥΤΟ ΠΑΣΤΕΡ (κατά ποσοστό 40%), Διαγνωστικος προσδιορισμος
JP2013528799A (ja) 2010-05-13 2013-07-11 ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー 神経変性疾患の検知および診断のための診断用自己抗体プロファイル
DE102011011280A1 (de) 2011-02-15 2012-08-16 Euroimmun Medizinische Labordiagnostika Ag Diagnosekit sowie ein Verfahren zur Untersuchung einer menschlichen Patientenprobe auf das Vorhandensein von Neuromyelitis-optica-spezifischen Antikörpern
KR20140059168A (ko) * 2011-04-21 2014-05-15 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 시신경 척수염 치료용 조성물 및 치료 방법
WO2013010003A1 (en) 2011-07-12 2013-01-17 University Of Medicine And Dentistry Of New Jersey Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease
CA2852469A1 (en) * 2011-10-21 2013-04-25 The Board Of Regents Of The University Of Texas System Codon signature for neuromyelitis optica
US10031139B2 (en) 2012-03-30 2018-07-24 Konica Minolta, Inc. Method for detecting biological material
WO2013177116A1 (en) * 2012-05-21 2013-11-28 The Regents Of The University Of California Enzymatic modification of anti-aqp4 autoantibody for modulating neuromyelitis optica
CN102898513B (zh) * 2012-10-31 2016-03-16 徐俊 ELISpot视神经脊髓炎诊断试剂盒及其应用
WO2014154907A1 (de) * 2013-03-28 2014-10-02 Protagen Ag Verfahren zur diagnose von neuromyelitis optica
EP3145528A4 (en) * 2014-05-19 2018-03-14 The Johns Hopkins University Highly soluble aquaporin-4 extracelluar loop c peptide immunization for treatment of neuromyelitis optica
WO2016001030A1 (en) * 2014-06-30 2016-01-07 Siemens Aktiengesellschaft Diagnosis of neuromyelitis optica vs. multiple sclerosis using mirna biomarkers
CN104698190A (zh) * 2015-03-16 2015-06-10 中国人民解放军总医院 用于中枢神经系统脱髓鞘疾病的生物诊断标记物
US10098935B2 (en) * 2015-05-01 2018-10-16 The Board Of Trustees Of The Leland Stanford Junior University Aquaporin tolerizing vaccines and methods of use thereof
EP3454920B1 (en) * 2016-05-13 2024-04-24 C. R. Bard, Inc. Peripherally inserted central catheter for pediatrics
CN106318974A (zh) * 2016-08-29 2017-01-11 南方医科大学南方医院 细胞固定工艺及通过该工艺制备aqp4抗体检测试剂盒
KR101977843B1 (ko) 2017-02-16 2019-05-13 국립암센터 시신경척수염 및 다발성경화증의 선별을 위한 바이오마커 및 이의 이용
WO2018190365A1 (ja) * 2017-04-12 2018-10-18 国立大学法人九州大学 神経障害性疼痛マーカー及びその使用
KR102089042B1 (ko) * 2017-05-16 2020-03-13 서울대학교병원 보체불활성화법을 이용한 항-아쿠아포린 4 항체의 개선된 검출 방법
CN108998450A (zh) * 2018-08-08 2018-12-14 昆明医科大学第附属医院 引物、cDNA、载体、AQP4单克隆抗体及制备方法
CN110618264A (zh) * 2019-09-10 2019-12-27 南方医科大学 基于量子点聚苯乙烯微球检测抗aqp4抗体的方法
CN111272998A (zh) * 2020-01-09 2020-06-12 天津天海新域生物科技有限公司 一种同时检测中枢脱髓鞘自身抗体aqp4、mog和mbp的方法
US20240082351A1 (en) * 2021-01-13 2024-03-14 Duke University Compositions for and methods of improving fluid flux in the brain
CN115232795B (zh) * 2021-07-22 2023-09-19 北京和合医学诊断技术股份有限公司 稳定表达aqp4-m23蛋白的细胞株及其构建方法、应用
CN113358881B (zh) * 2021-08-10 2021-11-30 首都医科大学附属北京天坛医院 用于nmosd预测或复发监测的生物标志物及其应用

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Also Published As

Publication number Publication date
JP2007518068A (ja) 2007-07-05
ATE424560T1 (de) 2009-03-15
US20080145870A1 (en) 2008-06-19
WO2005051178A3 (en) 2005-12-29
US20120219969A1 (en) 2012-08-30
US20050112116A1 (en) 2005-05-26
CN1910456B (zh) 2011-04-13
US7947254B2 (en) 2011-05-24
WO2005051178A2 (en) 2005-06-09
ES2320006T3 (es) 2009-05-18
EP1700120A4 (en) 2007-11-14
US20090143710A1 (en) 2009-06-04
US7101679B2 (en) 2006-09-05
US20140314796A1 (en) 2014-10-23
CN1910456A (zh) 2007-02-07
JP4538464B2 (ja) 2010-09-08
EP1700120A2 (en) 2006-09-13
DE602004019812D1 (de) 2009-04-16
US8524508B2 (en) 2013-09-03
EP1700120B1 (en) 2009-03-04

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