CN1910456B - 视神经脊髓炎的标记 - Google Patents

视神经脊髓炎的标记 Download PDF

Info

Publication number
CN1910456B
CN1910456B CN2004800408513A CN200480040851A CN1910456B CN 1910456 B CN1910456 B CN 1910456B CN 2004800408513 A CN2004800408513 A CN 2004800408513A CN 200480040851 A CN200480040851 A CN 200480040851A CN 1910456 B CN1910456 B CN 1910456B
Authority
CN
China
Prior art keywords
nmo
neuromyelitis optica
antigenic polypeptide
aquaporin
individual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN2004800408513A
Other languages
English (en)
Chinese (zh)
Other versions
CN1910456A (zh
Inventor
V·A·列农
T·J·克里泽尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Clinic in Florida
Original Assignee
Mayo Clinic in Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Clinic in Florida filed Critical Mayo Clinic in Florida
Publication of CN1910456A publication Critical patent/CN1910456A/zh
Application granted granted Critical
Publication of CN1910456B publication Critical patent/CN1910456B/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/285—Demyelinating diseases; Multipel sclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
CN2004800408513A 2003-11-25 2004-11-24 视神经脊髓炎的标记 Expired - Lifetime CN1910456B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/723,180 US7101679B2 (en) 2003-11-25 2003-11-25 Marker for neuromyelitis optica
US10/723,180 2003-11-25
PCT/US2004/039710 WO2005051178A2 (en) 2003-11-25 2004-11-24 Marker for neuromyelitis optica

Publications (2)

Publication Number Publication Date
CN1910456A CN1910456A (zh) 2007-02-07
CN1910456B true CN1910456B (zh) 2011-04-13

Family

ID=34592190

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800408513A Expired - Lifetime CN1910456B (zh) 2003-11-25 2004-11-24 视神经脊髓炎的标记

Country Status (9)

Country Link
US (5) US7101679B2 (enExample)
EP (1) EP1700120B1 (enExample)
JP (1) JP4538464B2 (enExample)
CN (1) CN1910456B (enExample)
AT (1) ATE424560T1 (enExample)
DE (1) DE602004019812D1 (enExample)
ES (1) ES2320006T3 (enExample)
IN (1) IN2014DN05011A (enExample)
WO (1) WO2005051178A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101679B2 (en) 2003-11-25 2006-09-05 Mayo Foundation For Medical Education And Research Marker for neuromyelitis optica
US20070093673A1 (en) * 2005-10-24 2007-04-26 Andre Vachereau Boron-containing compounds, uses and preparation thereof
JP4273235B2 (ja) * 2006-06-01 2009-06-03 国立大学法人 新潟大学 アクアポリン４阻害薬
US8889102B2 (en) * 2007-09-20 2014-11-18 Mayo Foundation For Medical Education And Research Neuromyelitis optica autoantibodies as a marker for neoplasia
JP5117336B2 (ja) * 2008-09-18 2013-01-16 国立大学法人 千葉大学 多発性硬化症またはｎｍｏの検査マーカーの測定方法
US9891219B2 (en) * 2008-10-10 2018-02-13 Mayo Foundation For Medical Education And Research Methods for treating neuromyelitis optica (NMO) by administration of eculizumab to an individual that is aquaporin-4 (AQP4)-IgG autoantibody positive
GR1007341B (el) 2010-04-21 2011-07-05 ΕΛΛΗΝΙΚΟ ΙΝΣΤΙΤΟΥΤΟ ΠΑΣΤΕΡ (κατά ποσοστό 40%), Διαγνωστικος προσδιορισμος
JP2013528799A (ja) 2010-05-13 2013-07-11 ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー 神経変性疾患の検知および診断のための診断用自己抗体プロファイル
DE102011011280A1 (de) 2011-02-15 2012-08-16 Euroimmun Medizinische Labordiagnostika Ag Diagnosekit sowie ein Verfahren zur Untersuchung einer menschlichen Patientenprobe auf das Vorhandensein von Neuromyelitis-optica-spezifischen Antikörpern
KR20140059168A (ko) * 2011-04-21 2014-05-15 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 시신경 척수염 치료용 조성물 및 치료 방법
WO2013010003A1 (en) 2011-07-12 2013-01-17 University Of Medicine And Dentistry Of New Jersey Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease
CA2852469A1 (en) * 2011-10-21 2013-04-25 The Board Of Regents Of The University Of Texas System Codon signature for neuromyelitis optica
US10031139B2 (en) 2012-03-30 2018-07-24 Konica Minolta, Inc. Method for detecting biological material
WO2013177116A1 (en) * 2012-05-21 2013-11-28 The Regents Of The University Of California Enzymatic modification of anti-aqp4 autoantibody for modulating neuromyelitis optica
CN102898513B (zh) * 2012-10-31 2016-03-16 徐俊 ELISpot视神经脊髓炎诊断试剂盒及其应用
WO2014154907A1 (de) * 2013-03-28 2014-10-02 Protagen Ag Verfahren zur diagnose von neuromyelitis optica
EP3145528A4 (en) * 2014-05-19 2018-03-14 The Johns Hopkins University Highly soluble aquaporin-4 extracelluar loop c peptide immunization for treatment of neuromyelitis optica
WO2016001030A1 (en) * 2014-06-30 2016-01-07 Siemens Aktiengesellschaft Diagnosis of neuromyelitis optica vs. multiple sclerosis using mirna biomarkers
CN104698190A (zh) * 2015-03-16 2015-06-10 中国人民解放军总医院 用于中枢神经系统脱髓鞘疾病的生物诊断标记物
US10098935B2 (en) * 2015-05-01 2018-10-16 The Board Of Trustees Of The Leland Stanford Junior University Aquaporin tolerizing vaccines and methods of use thereof
EP3454920B1 (en) * 2016-05-13 2024-04-24 C. R. Bard, Inc. Peripherally inserted central catheter for pediatrics
CN106318974A (zh) * 2016-08-29 2017-01-11 南方医科大学南方医院 细胞固定工艺及通过该工艺制备aqp4抗体检测试剂盒
KR101977843B1 (ko) 2017-02-16 2019-05-13 국립암센터 시신경척수염 및 다발성경화증의 선별을 위한 바이오마커 및 이의 이용
WO2018190365A1 (ja) * 2017-04-12 2018-10-18 国立大学法人九州大学 神経障害性疼痛マーカー及びその使用
KR102089042B1 (ko) * 2017-05-16 2020-03-13 서울대학교병원 보체불활성화법을 이용한 항-아쿠아포린 4 항체의 개선된 검출 방법
CN108998450A (zh) * 2018-08-08 2018-12-14 昆明医科大学第附属医院 引物、cDNA、载体、AQP4单克隆抗体及制备方法
CN110618264A (zh) * 2019-09-10 2019-12-27 南方医科大学 基于量子点聚苯乙烯微球检测抗aqp4抗体的方法
CN111272998A (zh) * 2020-01-09 2020-06-12 天津天海新域生物科技有限公司 一种同时检测中枢脱髓鞘自身抗体aqp4、mog和mbp的方法
US20240082351A1 (en) * 2021-01-13 2024-03-14 Duke University Compositions for and methods of improving fluid flux in the brain
CN115232795B (zh) * 2021-07-22 2023-09-19 北京和合医学诊断技术股份有限公司 稳定表达aqp4-m23蛋白的细胞株及其构建方法、应用
CN113358881B (zh) * 2021-08-10 2021-11-30 首都医科大学附属北京天坛医院 用于nmosd预测或复发监测的生物标志物及其应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US37273A (en) * 1863-01-06 Improved canteen
US4708713A (en) 1984-11-16 1987-11-24 Anisa Medical, Inc. Method and system for removing immunosuppressive components from the blood of mammals
US5258503A (en) 1987-09-08 1993-11-02 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Autoantibody adsorbent and apparatus for removing autoantibodies using the same
US5614192A (en) 1989-07-19 1997-03-25 Connective Therapeutics, Inc. T cell receptor peptides as therapeutics for immune-related disease
US5214136A (en) 1990-02-20 1993-05-25 Gilead Sciences, Inc. Anthraquinone-derivatives oligonucleotides
US5218105A (en) 1990-07-27 1993-06-08 Isis Pharmaceuticals Polyamine conjugated oligonucleotides
US5741671A (en) * 1991-12-12 1998-04-21 The Johns Hopkins University Isolation cloning and expression of transmembrane water channel aquaporin 1(AQP1)
US5324638A (en) 1992-05-13 1994-06-28 Sloan-Kettering Institute For Cancer Research Brain transcription factor, nucleic acids encoding same and uses thereof
DE4227695C1 (de) 1992-08-21 1993-10-07 Fresenius Ag Zentrifuge zum Auftrennen von Blut in seine Bestandteile
US5676644A (en) 1995-06-07 1997-10-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
WO1997017369A2 (en) 1995-11-09 1997-05-15 Trustees Of Boston University Dna comprising a neuron-specific transcriptional promoter and its use in a gene therapy vector
AU763929B2 (en) 1998-11-25 2003-08-07 Amarillo Biosciences, Inc. Interferon-alpha mediated upregulation of aquaporin expression
US20040014087A1 (en) 1999-06-01 2004-01-22 Incyte Corporation Molecules for diagnostics and therapeutics
US6409726B1 (en) * 1999-11-08 2002-06-25 Alan G. Ellman Electrosurgical instrument for ear surgery
US20030072737A1 (en) 2000-12-29 2003-04-17 Michael Brines Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
US20040048253A1 (en) 2001-02-21 2004-03-11 Panzer Scott R. Molecules for diagnostics and therapeutics
US7251568B2 (en) 2001-04-18 2007-07-31 Wyeth Methods and compositions for regulating bone and cartilage formation
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20040115629A1 (en) 2002-01-09 2004-06-17 Panzer Scott R Molecules for diagnostics and therapeutics
EP1376773B1 (de) * 2002-06-22 2006-08-16 Spinner GmbH Koaxialer Steckverbinder
US7101679B2 (en) 2003-11-25 2006-09-05 Mayo Foundation For Medical Education And Research Marker for neuromyelitis optica

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Haase CG and Schmidt S..Detection of brain-specific autoantibodies tomyelinoligodendrocyte glycoprotein, S100 beta and myelinbasicprotein in patients with Devic＇s neuromyelitis optica..Neuroscience Letters.307 2.2001,307(2),131-133..
Haase CG and Schmidt S..Detection of brain-specific autoantibodies tomyelinoligodendrocyte glycoprotein, S100 beta and myelinbasicprotein in patients with Devic＇s neuromyelitis optica..Neuroscience Letters.307 2.2001,307(2),131-133.. *
朱雨岚,王维治..视神经脊髓炎(Devic＇s综合症)临床研究进展.国外医学 神经病学神经外科学分册28 2.2001,28(2),90-93. *
朱雨岚，王维治。.视神经脊髓炎（Devic＇s综合症）临床研究进展.国外医学 神经病学神经外科学分册28 2.2001,28(2),90-93.

Also Published As

Publication number Publication date
JP2007518068A (ja) 2007-07-05
ATE424560T1 (de) 2009-03-15
US20080145870A1 (en) 2008-06-19
WO2005051178A3 (en) 2005-12-29
US20120219969A1 (en) 2012-08-30
US20050112116A1 (en) 2005-05-26
US7947254B2 (en) 2011-05-24
WO2005051178A2 (en) 2005-06-09
ES2320006T3 (es) 2009-05-18
EP1700120A4 (en) 2007-11-14
US20090143710A1 (en) 2009-06-04
US7101679B2 (en) 2006-09-05
US20140314796A1 (en) 2014-10-23
IN2014DN05011A (enExample) 2015-07-10
CN1910456A (zh) 2007-02-07
JP4538464B2 (ja) 2010-09-08
EP1700120A2 (en) 2006-09-13
DE602004019812D1 (de) 2009-04-16
US8524508B2 (en) 2013-09-03
EP1700120B1 (en) 2009-03-04

Similar Documents

Publication Publication Date Title
CN1910456B (zh) 视神经脊髓炎的标记
JP2014527398A (ja) がんの療法および診断のための組成物および方法
AU2014366827A1 (en) Method of diagnosis and treatment
JP2009284907A (ja) 膵癌の診断および治療のための方法、ならびにそれらに有用な組成物
US20130017206A1 (en) Mcam modulation and uses thereof
JP2020530978A (ja) Ｈｌａ−ｇ転写物およびアイソフォームおよびそれらの使用
KR20220122467A (ko) 사스-코로나바이러스-2에 특이적으로 결합하는 항체 및 그의 용도
CN110824156B (zh) 神经自身免疫疾病的诊断
US20100098715A1 (en) Annexin ii compositions for treating or monitoring inflammation or immune-mediated disorders
CN102778566B (zh) Dlk1在肝癌诊断及预后判断中的应用
JP7326108B2 (ja) 自己免疫性水疱症の診断
WO2024182718A2 (en) Compositions and methods related to transcobalamin receptor autoantibodies
WO2007039489A1 (en) Antibodies against april as biomarkers for early prognosis of lymphoma patients
US20140377883A1 (en) Peripherin-specific autoantibodies as a marker for neurological and endocrinological disease
US20140294850A1 (en) Early childhood membranous nephropathy due to cationic bovine serum albumin
CN111175484A (zh) 神经自身免疫性疾病的诊断
US20220120744A1 (en) Assessing and treating germ cell tumors and paraneoplastic autoimmunity
AU2009212789B2 (en) Ninjurin-1 and/or MCAM Modulation and Uses Thereof
CN112285363A (zh) 自身免疫类神经疾病的诊断
CA2790883A1 (en) Antibodies, compositions, and assays for detection of cardiac disease
WO2003052417A1 (fr) Methode de detection de granulysine extracellulaire

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term

Granted publication date: 20110413

CX01 Expiry of patent term