IN2014CN04671A - - Google Patents
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- Publication number
- IN2014CN04671A IN2014CN04671A IN4671CHN2014A IN2014CN04671A IN 2014CN04671 A IN2014CN04671 A IN 2014CN04671A IN 4671CHN2014 A IN4671CHN2014 A IN 4671CHN2014A IN 2014CN04671 A IN2014CN04671 A IN 2014CN04671A
- Authority
- IN
- India
- Prior art keywords
- compounds
- poly
- pharmaceutical compositions
- present
- treating diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11190687 | 2011-11-25 | ||
EP12161489 | 2012-03-27 | ||
PCT/EP2012/073125 WO2013076090A1 (en) | 2011-11-25 | 2012-11-20 | 3-phenyl-isoquinolin-1(2h)-one derivatives as parp-1 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN04671A true IN2014CN04671A (ru) | 2015-09-18 |
Family
ID=47227787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN4671CHN2014 IN2014CN04671A (ru) | 2011-11-25 | 2012-11-20 |
Country Status (15)
Country | Link |
---|---|
US (1) | US9422243B2 (ru) |
EP (1) | EP2788328B1 (ru) |
JP (1) | JP6106182B2 (ru) |
KR (1) | KR20140097457A (ru) |
CN (1) | CN103946214B (ru) |
AU (1) | AU2012342562B2 (ru) |
BR (1) | BR112014012031A2 (ru) |
CA (1) | CA2856759A1 (ru) |
CL (1) | CL2014001323A1 (ru) |
EA (1) | EA027800B1 (ru) |
ES (1) | ES2676068T3 (ru) |
HK (1) | HK1200166A1 (ru) |
IN (1) | IN2014CN04671A (ru) |
MX (1) | MX2014006015A (ru) |
WO (1) | WO2013076090A1 (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2611504T3 (es) | 2012-03-07 | 2017-05-09 | Institute Of Cancer Research: Royal Cancer Hospital (The) | Compuestos de isoquinolin-1-ona 3-aril-5-sustituida y sus usos terapéuticos |
AU2014320149A1 (en) * | 2013-09-11 | 2016-04-07 | Institute Of Cancer Research: Royal Cancer Hospital (The) | 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use |
EP3094752A4 (en) * | 2014-01-16 | 2017-08-16 | Clovis Oncology, Inc. | Use of parp inhibitors to treat breast or ovarian cancer patients showing a loss of heterozygosity |
MX2018005215A (es) | 2015-11-06 | 2018-08-01 | Neurocrine Biosciences Inc | Derivados de n-[2-(1-bencilpiperidin-4-il)etil]-4-(pirazin-2-il)-p iperazin-1-carboxamida y compuestos relacionados como antagonistas del receptor muscarinico 4 (m4) para el tratamiento de enfermedades neurologicas. |
WO2023242302A1 (en) | 2022-06-15 | 2023-12-21 | Astrazeneca Ab | Combination therapy for treating cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004528376A (ja) | 2001-05-08 | 2004-09-16 | クドス ファーマシューティカルズ リミテッド | Parp阻害薬としてのイソキノリノン誘導体 |
EP1396488A1 (en) | 2001-05-23 | 2004-03-10 | Mitsubishi Pharma Corporation | Fused heterocyclic compound and medicinal use thereof |
US7425563B2 (en) * | 2002-07-24 | 2008-09-16 | Kyorin Pharmaceutical Co., Ltd. | 4-(Substituted aryl)-5-hydroxyisoquinolinone derivative |
EP2254888B1 (en) * | 2008-02-22 | 2014-12-24 | Msd K.K. | Novel aminopyridine derivatives having aurora a selective inhibitory action |
TWI499418B (zh) * | 2009-05-21 | 2015-09-11 | Nerviano Medical Sciences Srl | 異喹啉-1(2h)-酮衍生物 |
-
2012
- 2012-11-20 EA EA201491026A patent/EA027800B1/ru not_active IP Right Cessation
- 2012-11-20 ES ES12791464.6T patent/ES2676068T3/es active Active
- 2012-11-20 BR BR112014012031A patent/BR112014012031A2/pt not_active IP Right Cessation
- 2012-11-20 MX MX2014006015A patent/MX2014006015A/es unknown
- 2012-11-20 EP EP12791464.6A patent/EP2788328B1/en active Active
- 2012-11-20 US US14/358,537 patent/US9422243B2/en active Active
- 2012-11-20 KR KR1020147017409A patent/KR20140097457A/ko not_active Application Discontinuation
- 2012-11-20 WO PCT/EP2012/073125 patent/WO2013076090A1/en active Application Filing
- 2012-11-20 JP JP2014542801A patent/JP6106182B2/ja active Active
- 2012-11-20 IN IN4671CHN2014 patent/IN2014CN04671A/en unknown
- 2012-11-20 AU AU2012342562A patent/AU2012342562B2/en not_active Ceased
- 2012-11-20 CN CN201280057586.4A patent/CN103946214B/zh active Active
- 2012-11-20 CA CA2856759A patent/CA2856759A1/en not_active Abandoned
-
2014
- 2014-05-20 CL CL2014001323A patent/CL2014001323A1/es unknown
-
2015
- 2015-01-16 HK HK15100542.6A patent/HK1200166A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2856759A1 (en) | 2013-05-30 |
AU2012342562A1 (en) | 2014-07-10 |
EP2788328B1 (en) | 2018-01-31 |
BR112014012031A2 (pt) | 2017-05-30 |
JP6106182B2 (ja) | 2017-03-29 |
CN103946214A (zh) | 2014-07-23 |
CN103946214B (zh) | 2016-08-17 |
US20140336192A1 (en) | 2014-11-13 |
JP2014533709A (ja) | 2014-12-15 |
HK1200166A1 (en) | 2015-07-31 |
US9422243B2 (en) | 2016-08-23 |
ES2676068T3 (es) | 2018-07-16 |
MX2014006015A (es) | 2014-06-04 |
KR20140097457A (ko) | 2014-08-06 |
AU2012342562B2 (en) | 2017-02-23 |
CL2014001323A1 (es) | 2014-09-05 |
WO2013076090A1 (en) | 2013-05-30 |
EA027800B1 (ru) | 2017-09-29 |
EA201491026A1 (ru) | 2014-11-28 |
EP2788328A1 (en) | 2014-10-15 |
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