IN2014CN03508A - - Google Patents

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Publication number
IN2014CN03508A
IN2014CN03508A IN3508CHN2014A IN2014CN03508A IN 2014CN03508 A IN2014CN03508 A IN 2014CN03508A IN 3508CHN2014 A IN3508CHN2014 A IN 3508CHN2014A IN 2014CN03508 A IN2014CN03508 A IN 2014CN03508A
Authority
IN
India
Prior art keywords
sample
analyte
eis
measurement
nucleic acid
Prior art date
Application number
Other languages
English (en)
Inventor
Holger Schulze
Damion Corrigan
Till Bachmann
Original Assignee
Iti Scotland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iti Scotland Ltd filed Critical Iti Scotland Ltd
Publication of IN2014CN03508A publication Critical patent/IN2014CN03508A/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60Detection means characterised by use of a special device
    • C12Q2565/607Detection means characterised by use of a special device being a sensor, e.g. electrode
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
IN3508CHN2014 2011-11-22 2012-11-21 IN2014CN03508A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1120118.3A GB201120118D0 (en) 2011-11-22 2011-11-22 Detecting analytes
GB1212662.9A GB2496932A (en) 2011-11-22 2012-07-17 Nucleic acid detection using electrochemical impedance spectroscopy
PCT/EP2012/073240 WO2013076143A1 (en) 2011-11-22 2012-11-21 Detecting analytes

Publications (1)

Publication Number Publication Date
IN2014CN03508A true IN2014CN03508A (ko) 2015-10-09

Family

ID=45475523

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3508CHN2014 IN2014CN03508A (ko) 2011-11-22 2012-11-21

Country Status (13)

Country Link
US (1) US9777337B2 (ko)
EP (1) EP2776583A1 (ko)
JP (1) JP2015503095A (ko)
KR (1) KR20140096104A (ko)
CN (1) CN104145026A (ko)
AU (1) AU2012342522A1 (ko)
BR (1) BR112014012045A2 (ko)
GB (2) GB201120118D0 (ko)
IN (1) IN2014CN03508A (ko)
MX (1) MX2014006118A (ko)
RU (1) RU2014125212A (ko)
WO (1) WO2013076143A1 (ko)
ZA (1) ZA201404463B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201415864D0 (en) 2014-09-08 2014-10-22 Univ Edinburgh Methods of detecting of multidrug resistant bacteria
US10101275B2 (en) * 2015-01-13 2018-10-16 Arkray, Inc. Plasma spectrochemical analysis method and plasma spectrochemical analyzer
WO2016127077A2 (en) 2015-02-06 2016-08-11 Genapsys, Inc Systems and methods for detection and analysis of biological species
JP6876920B2 (ja) * 2015-02-20 2021-05-26 ソニーグループ株式会社 電気的特性測定装置、電気的特性測定システム、電気的特性測定方法、及び該方法をコンピューターに実現させるための電気的特性測定用プログラム
CN104914151B (zh) * 2015-05-08 2017-10-13 首都师范大学 一种用于氨苄西林和磺胺地索辛电化学传感器自组装钝化层的形成方法及其电化学传感器
US11486873B2 (en) 2016-03-31 2022-11-01 Ontera Inc. Multipore determination of fractional abundance of polynucleotide sequences in a sample
US10012645B2 (en) * 2016-08-24 2018-07-03 The Florida International University Board Of Trustees Rapid zika virus detection using nano-enabled electrochemical sensing system
MX2018013686A (es) * 2016-10-24 2019-05-02 Two Pore Guys Inc Abundancia fraccional de secuencias de polinucleotidos en una muestra.
WO2019026517A1 (ja) * 2017-07-31 2019-02-07 国立大学法人大阪大学 溶液中に存在する対象物質の検出方法および検出するためのシステム
CN108152250B (zh) * 2017-10-27 2020-02-18 南京邮电大学 生物识别探针的构建方法及其逻辑运算方法
KR102294374B1 (ko) * 2019-09-09 2021-08-26 한국교통대학교산학협력단 전기화학적 무선 진단이 가능한 탄소 양자점의 제조방법, 및 이를 활용한 전기화학적 무선진단방법
CN111562254A (zh) * 2020-05-27 2020-08-21 济南大学 一种基于功能化磁性二氧化硅的化学发光传感器的制备方法
WO2024235904A1 (en) * 2023-05-16 2024-11-21 Roche Molecular Systems, Inc. Detection of target analytes using multimodal signal probes

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4274561B2 (ja) * 1997-08-01 2009-06-10 キヤノン株式会社 プローブアレイとその製造方法
EP1144685B1 (de) 1999-01-18 2003-04-23 Friz Biochem GmbH Verfahren zur elektrochemischen detektion von nukleinsäure -oligomer- hybridisierungsereignissen
US6265170B1 (en) * 2000-01-24 2001-07-24 Ingeneus Corporation Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions
JP2002286736A (ja) 2001-03-28 2002-10-03 Canon Inc プローブ担体の製造方法およびプローブ担体の製造装置
JP2004177399A (ja) 2002-11-14 2004-06-24 Toyama Prefecture ハイブリダイゼーションの検出方法
US20060275786A1 (en) 2003-03-05 2006-12-07 Yi-Tao Long Electrochemical detection of DNA binding
DE10311315A1 (de) 2003-03-14 2004-09-30 Apibio Sas Verfahren und Vorrichtung zur Detektion von Biomolekülen
DE602004022042D1 (de) 2003-05-13 2009-08-27 Gen Probe Inc Verfahren und kit zur identifizierung antibiotikaresistenter mikroorganismen
US8252533B2 (en) 2007-02-23 2012-08-28 Panagene Inc. Method for increasing efficiency or specificity of hybridization between PNA probes immobilized on support and target nucleic acids
KR101072900B1 (ko) 2007-12-04 2011-10-17 주식회사 파나진 고정화된 펩티드핵산 프로브를 사용한 표적핵산의 선택적 표지 및 검출 방법
GB0804491D0 (en) 2008-03-11 2008-04-16 Iti Scotland Ltd Detecting analytes
GB0805814D0 (en) * 2008-03-31 2008-04-30 Cambridge Entpr Ltd Biosensor for analyte detection
WO2010060060A1 (en) * 2008-11-24 2010-05-27 Adnavance Technologies, Inc. Electrochemical methods of detecting nucleic acid hybridization
CN102753965B (zh) 2009-12-09 2016-01-13 Iti苏格兰有限公司 检测分析物

Also Published As

Publication number Publication date
GB2496932A (en) 2013-05-29
KR20140096104A (ko) 2014-08-04
AU2012342522A1 (en) 2014-05-29
WO2013076143A1 (en) 2013-05-30
MX2014006118A (es) 2015-04-16
BR112014012045A2 (pt) 2017-05-30
US9777337B2 (en) 2017-10-03
JP2015503095A (ja) 2015-01-29
GB201212662D0 (en) 2012-08-29
GB201120118D0 (en) 2012-01-04
CN104145026A (zh) 2014-11-12
US20150148257A1 (en) 2015-05-28
RU2014125212A (ru) 2015-12-27
EP2776583A1 (en) 2014-09-17
ZA201404463B (en) 2015-10-28

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