IN2013MU03670A - - Google Patents

Info

Publication number
IN2013MU03670A
IN2013MU03670A IN3670MU2013A IN2013MU03670A IN 2013MU03670 A IN2013MU03670 A IN 2013MU03670A IN 3670MU2013 A IN3670MU2013 A IN 3670MU2013A IN 2013MU03670 A IN2013MU03670 A IN 2013MU03670A
Authority
IN
India
Prior art keywords
solvates
hydrates
intermediates
phenyl
formula
Prior art date
Application number
Other languages
English (en)
Inventor
Ashok J Kalaria
Mukesh Kumar
Ankur A Sidhdhpura
Yogendra Chauhan
Original Assignee
Unimark Remedies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unimark Remedies Ltd filed Critical Unimark Remedies Ltd
Priority to PCT/IB2014/066225 priority Critical patent/WO2015075678A1/en
Priority to IN3670MU2013 priority patent/IN2013MU03670A/en
Publication of IN2013MU03670A publication Critical patent/IN2013MU03670A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
IN3670MU2013 2013-11-21 2014-11-21 IN2013MU03670A (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/IB2014/066225 WO2015075678A1 (en) 2013-11-21 2014-11-21 A novel process for the preparation of 1-phenyl-3-aminopropane derivatives
IN3670MU2013 IN2013MU03670A (de) 2013-11-21 2014-11-21

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3670MU2013 IN2013MU03670A (de) 2013-11-21 2014-11-21

Publications (1)

Publication Number Publication Date
IN2013MU03670A true IN2013MU03670A (de) 2015-07-31

Family

ID=52144778

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3670MU2013 IN2013MU03670A (de) 2013-11-21 2014-11-21

Country Status (2)

Country Link
IN (1) IN2013MU03670A (de)
WO (1) WO2015075678A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2539442A (en) * 2015-06-16 2016-12-21 Azad Pharmaceutical Ingredients Ag New synthesis of tapentadol-HCI intermediates

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE19933421A1 (de) 1999-07-16 2001-01-25 Gruenenthal Gmbh 2-Benzyl-3-dimethylamino-1-phenyl-propanderi- vate
DE10326097A1 (de) 2003-06-06 2005-01-05 Grünenthal GmbH Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen
DE10328316A1 (de) 2003-06-23 2005-01-20 Grünenthal GmbH Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE102005033732B4 (de) 2005-05-27 2014-02-13 Grünenthal GmbH Trennung stereoisomerer N,N-Dialkylamino-2-alkyl-3-hydroxy-3-phenyl-alkane
TWI401237B (zh) 2006-07-24 2013-07-11 ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備
PT2046726E (pt) 2006-07-24 2010-04-15 Janssen Pharmaceutica Nv Preparação da (2r,3r)-3-(3-metoxifenil)-n,n,2- trimetilpentanamina
TWI448447B (zh) 2006-07-24 2014-08-11 Gruenenthal Chemie 製備（１ｒ，２ｒ）-３-（３-二甲胺基-１-乙基-２-甲基-丙基）-酚之方法
CN102002065B (zh) 2009-09-02 2014-09-10 上海特化医药科技有限公司 他喷他多的制备方法及其中间体
IT1397189B1 (it) 2009-12-01 2013-01-04 Archimica Srl Nuovo processo per la preparazione di tapentadol e suoi intermedi.
MX2012007759A (es) 2009-12-29 2012-08-01 Mapi Pharma Ltd Compuestos intermedios y procesos para la preparacion de tapentadol y compuestos relacionados.
WO2011080756A1 (en) 2009-12-29 2011-07-07 Ind-Swift Laboratories Limited Process for the preparation of 1-phenyl-3-dimethylaminopropane derivatives
WO2011092719A2 (en) 2010-02-01 2011-08-04 Ind-Swift Laboratories Limited Process for the preparation of l-phenyl-3-dimethylaminopropane derivatives
CA2790519A1 (en) 2010-03-05 2011-09-09 Actavis Group Ptc Ehf Improved resolution methods for isolating desired enantiomers of tapentadol intermediates and use thereof for the preparation of tapentadol
US20130096347A1 (en) * 2010-04-05 2013-04-18 Actavis Group Ptc Ehf Novel process for preparing highly pure tapentadol or a pharmaceutically acceptable salt thereof
WO2012051246A1 (en) * 2010-10-12 2012-04-19 Ratiopharm Gmbh Tapentadol hydrobromide and crystalline forms thereof
CN102320984B (zh) 2011-07-25 2014-04-02 江苏恩华药业股份有限公司 (r)-3-(3-甲氧基苯基)-n,n,2-三甲基戊-3-烯-1-胺的制备方法
EP2674414A1 (de) 2012-06-15 2013-12-18 Siegfried AG Verfahren zur Herstellung von 1-aryl-1-alkyl-3-dialkylaminopropan-Verbindungen
CN102936205B (zh) 2012-11-12 2014-06-18 合肥市新星医药化工有限公司 一种他喷他多的合成方法

Also Published As

Publication number Publication date
WO2015075678A1 (en) 2015-05-28

Similar Documents

Publication Publication Date Title
PH12015502031A1 (en) Tetrahydropyrrolothiazine compounds
PH12020551628A1 (en) A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
CO6852084A2 (es) Nuevos compuestos sustituidos con halógeno
TW201613853A (en) Synthesis of polycyclic-carbamoylpyridone compounds
IN2014CH00247A (de)
PH12017500833A1 (en) Synthesis of copanlisib and its dihydrochloride salt
MX2016010973A (es) Compuestos de aminocarbonilcarbamato.
MX2015015841A (es) Compuestos de fenoxietil dihidro-1h-isoquinolina.
JOP20200030A1 (ar) مركب خماسي الحلقة
IN2013MU03862A (de)
PH12017501404A1 (en) Diaza-benzofluoranthrene compounds
IN2014MU01192A (de)
IN2014MU00195A (de)
MX2016007186A (es) Nuevo procedimiento de sintesis de la agomelatina.
GB2564185A (en) Process for the preparation of derivatives of benzodioxole
IN2013MU03670A (de)
IN2014MU00194A (de)
IN2014MU01196A (de)
IN2013MU03565A (de)
MX2014012822A (es) Proceso para elaborar derivados de naftiridina.
IN2013MU01219A (de)
IN2014MU00072A (de)
IN2013MU02010A (de)
IN2013MU00777A (de)
IN2014MU00070A (de)