IN2013MU03442A - - Google Patents
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- Publication number
- IN2013MU03442A IN2013MU03442A IN3442MU2013A IN2013MU03442A IN 2013MU03442 A IN2013MU03442 A IN 2013MU03442A IN 3442MU2013 A IN3442MU2013 A IN 3442MU2013A IN 2013MU03442 A IN2013MU03442 A IN 2013MU03442A
- Authority
- IN
- India
- Prior art keywords
- glycerol
- present
- phenylbutyrate
- reacting
- iii
- Prior art date
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- VQDQISMDUHBUFF-UHFFFAOYSA-N 4-phenylbutanoyl chloride Chemical compound ClC(=O)CCCC1=CC=CC=C1 VQDQISMDUHBUFF-UHFFFAOYSA-N 0.000 abstract 2
- 229960002815 glycerol phenylbutyrate Drugs 0.000 abstract 2
- ZSDBFLMJVAGKOU-UHFFFAOYSA-N glycerol phenylbutyrate Chemical compound C=1C=CC=CC=1CCCC(=O)OCC(OC(=O)CCCC=1C=CC=CC=1)COC(=O)CCCC1=CC=CC=C1 ZSDBFLMJVAGKOU-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000004128 high performance liquid chromatography Methods 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2014/065578 WO2015063659A1 (en) | 2013-10-30 | 2014-10-24 | Process for the preparation of glycerol phenylbutyrate |
| IN3442MU2013 IN2013MU03442A (is") | 2013-10-30 | 2014-10-24 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3442MU2013 IN2013MU03442A (is") | 2013-10-30 | 2014-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MU03442A true IN2013MU03442A (is") | 2015-07-17 |
Family
ID=51982661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3442MU2013 IN2013MU03442A (is") | 2013-10-30 | 2014-10-24 |
Country Status (2)
| Country | Link |
|---|---|
| IN (1) | IN2013MU03442A (is") |
| WO (1) | WO2015063659A1 (is") |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2760479B1 (en) | 2011-09-30 | 2017-05-03 | Horizon Therapeutics, LLC | Nitrogen scavenging drug for use in a method of treating a nitrogen retention disorder |
| US9914692B2 (en) | 2016-05-25 | 2018-03-13 | Horizon Therapeutics, Llc | Procedure for the preparation of 4-phenyl butyrate and uses thereof |
| CN106117045A (zh) * | 2016-06-22 | 2016-11-16 | 北京阳光诺和药物研究有限公司 | 一种苯基丁酸的纯化方法 |
| US20190076383A1 (en) * | 2017-09-08 | 2019-03-14 | Horizon Therapeutics, Llc | Methods for treating urea cycle disorders |
| US10668040B2 (en) | 2017-09-11 | 2020-06-02 | Horizon Therapeutics, Llc | Treatment of urea cycle disorders in neonates and infants |
| WO2020070760A1 (en) * | 2018-10-04 | 2020-04-09 | Msn Laboratories Private Limited, R&D Center | An improved process for the preparation of 1,2,3-propanetriyl tris(4-phenylbutanoate) |
| CN113845420B (zh) * | 2021-10-22 | 2024-04-16 | 安徽沃泰生物医药有限公司 | 苯丁酸甘油酯的合成工艺 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE201013T1 (de) | 1995-02-07 | 2001-05-15 | Brusilow Entpr Llc | Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen |
| IT1317073B1 (it) | 2000-12-12 | 2003-05-26 | Mini Ricerca Scient Tecnolog | Esteri dell'acido fenilbutirrico, procedimenti per la loro produzionee loro impiego terapeutico. |
| EP2607366A1 (en) | 2011-12-21 | 2013-06-26 | Lunamed AG | Glycerol phenyl butyrate esters |
-
2014
- 2014-10-24 IN IN3442MU2013 patent/IN2013MU03442A/en unknown
- 2014-10-24 WO PCT/IB2014/065578 patent/WO2015063659A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015063659A1 (en) | 2015-05-07 |
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