IN2013MU00916A - - Google Patents
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- Publication number
- IN2013MU00916A IN2013MU00916A IN916MU2013A IN2013MU00916A IN 2013MU00916 A IN2013MU00916 A IN 2013MU00916A IN 916MU2013 A IN916MU2013 A IN 916MU2013A IN 2013MU00916 A IN2013MU00916 A IN 2013MU00916A
- Authority
- IN
- India
- Prior art keywords
- formula
- preparation
- relates
- improved process
- sitagliptin phosphate
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 2
- 150000004682 monohydrates Chemical class 0.000 abstract 1
- 229960004034 sitagliptin Drugs 0.000 abstract 1
- MFFMDFFZMYYVKS-SECBINFHSA-N sitagliptin Chemical compound C([C@H](CC(=O)N1CC=2N(C(=NN=2)C(F)(F)F)CC1)N)C1=CC(F)=C(F)C=C1F MFFMDFFZMYYVKS-SECBINFHSA-N 0.000 abstract 1
- 229960004115 sitagliptin phosphate Drugs 0.000 abstract 1
- RTZRUVMEWWPNRR-UHFFFAOYSA-N tert-butyl n-(3-iodo-1h-pyrrolo[2,3-b]pyridin-5-yl)carbamate Chemical compound CC(C)(C)OC(=O)NC1=CN=C2NC=C(I)C2=C1 RTZRUVMEWWPNRR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN916MU2013 IN2013MU00916A (enrdf_load_html_response) | 2013-03-20 | 2013-03-20 | |
| US14/220,836 US9409912B2 (en) | 2013-03-20 | 2014-03-20 | Process for the preparation of sitagliptin phosphate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN916MU2013 IN2013MU00916A (enrdf_load_html_response) | 2013-03-20 | 2013-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MU00916A true IN2013MU00916A (enrdf_load_html_response) | 2015-06-26 |
Family
ID=52691500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN916MU2013 IN2013MU00916A (enrdf_load_html_response) | 2013-03-20 | 2013-03-20 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US9409912B2 (enrdf_load_html_response) |
| IN (1) | IN2013MU00916A (enrdf_load_html_response) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105175422B (zh) * | 2015-09-18 | 2018-04-20 | 深圳市海滨制药有限公司 | 一种磷酸西格列汀晶体及其制备方法和用途 |
| CN106124667B (zh) * | 2016-08-29 | 2018-07-31 | 上海应用技术学院 | 一种分离测定西格列汀有关物质的方法 |
| CN109651373A (zh) * | 2017-10-11 | 2019-04-19 | 江苏瑞科医药科技有限公司 | 一种西格列汀磷酸盐单水合物晶型的制备方法 |
| CN114262331A (zh) * | 2020-09-16 | 2022-04-01 | 江苏万邦生化医药集团有限责任公司 | 一种西格列汀磷酸盐一水合物的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
| JO2625B1 (en) | 2003-06-24 | 2011-11-01 | ميرك شارب اند دوم كوربوريشن | Phosphoric acid salts of dipeptidyl betidase inhibitor 4 |
| TW200602293A (en) | 2004-04-05 | 2006-01-16 | Merck & Co Inc | Process for the preparation of enantiomerically enriched beta amino acid derivatives |
| US20090123983A1 (en) | 2007-10-03 | 2009-05-14 | Valerie Niddam-Hildesheim | Processes for preparing an intermediate of sitagliptin via enzymatic reduction |
| US8334385B2 (en) * | 2007-11-02 | 2012-12-18 | Glenmark Generics Limited | Process for the preparation of R-sitagliptin and its pharmaceutically acceptable salts thereof |
| US20090192326A1 (en) | 2007-11-13 | 2009-07-30 | Nurit Perlman | Preparation of sitagliptin intermediate |
| CA2707790C (en) * | 2007-12-20 | 2015-04-21 | Dr. Reddy's Laboratories Limited | Processes for the preparation of sitagliptin and pharmaceutically acceptable salts thereof |
| EP2324027B1 (en) * | 2008-07-29 | 2016-02-24 | Medichem, S.A. | New crystalline salt forms of a 5,6,7,8-tetrahydro-1,2,4- triazolo[4,3-a]pyrazine derivative |
| WO2010122578A2 (en) | 2009-04-20 | 2010-10-28 | Msn Laboratories Limited | Process for the preparation of sitagliptin and its intermediates |
| JP6199556B2 (ja) * | 2009-05-11 | 2017-09-20 | ジェネリクス・［ユーケー］・リミテッド | シタグリプチンの合成 |
| KR101222679B1 (ko) * | 2009-10-21 | 2013-01-16 | 한미사이언스 주식회사 | 시타글립틴의 제조 방법 및 이에 사용되는 중간체 |
| ITMI20110765A1 (it) * | 2011-05-05 | 2012-11-06 | Chemo Iberica Sa | Processo per la produzione di sitagliptina |
| WO2013013833A1 (en) | 2011-07-27 | 2013-01-31 | Farma Grs, D.O.O. | Process for the preparation of sitagliptin and its pharmaceutically acceptable salts |
-
2013
- 2013-03-20 IN IN916MU2013 patent/IN2013MU00916A/en unknown
-
2014
- 2014-03-20 US US14/220,836 patent/US9409912B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20150087834A1 (en) | 2015-03-26 |
| US9409912B2 (en) | 2016-08-09 |