IN2013MU01113A - - Google Patents
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- Publication number
- IN2013MU01113A IN2013MU01113A IN1113MU2013A IN2013MU01113A IN 2013MU01113 A IN2013MU01113 A IN 2013MU01113A IN 1113MU2013 A IN1113MU2013 A IN 1113MU2013A IN 2013MU01113 A IN2013MU01113 A IN 2013MU01113A
- Authority
- IN
- India
- Prior art keywords
- rivaroxaban
- preparation
- relates
- present
- Prior art date
Links
- KGFYHTZWPPHNLQ-AWEZNQCLSA-N rivaroxaban Chemical compound S1C(Cl)=CC=C1C(=O)NC[C@@H]1OC(=O)N(C=2C=CC(=CC=2)N2C(COCC2)=O)C1 KGFYHTZWPPHNLQ-AWEZNQCLSA-N 0.000 abstract 1
- 229960001148 rivaroxaban Drugs 0.000 abstract 1
Classifications
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
 
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
 
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| IN1113MU2013 IN2013MU01113A (enrdf_load_html_response) | 2013-03-25 | 2014-03-21 | |
| PCT/IB2014/060028 WO2014155259A2 (en) | 2013-03-25 | 2014-03-21 | Process for the preparation of rivaroxaban | 
| US14/780,138 US9663505B2 (en) | 2013-03-25 | 2014-03-21 | Process for the preparation of rivaroxaban | 
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| IN1113MU2013 IN2013MU01113A (enrdf_load_html_response) | 2013-03-25 | 2014-03-21 | 
Publications (1)
| Publication Number | Publication Date | 
|---|---|
| IN2013MU01113A true IN2013MU01113A (enrdf_load_html_response) | 2015-06-19 | 
Family
ID=51625556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| IN1113MU2013 IN2013MU01113A (enrdf_load_html_response) | 2013-03-25 | 2014-03-21 | 
Country Status (3)
| Country | Link | 
|---|---|
| US (1) | US9663505B2 (enrdf_load_html_response) | 
| IN (1) | IN2013MU01113A (enrdf_load_html_response) | 
| WO (1) | WO2014155259A2 (enrdf_load_html_response) | 
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| CN109553611A (zh) * | 2017-09-23 | 2019-04-02 | 齐鲁制药有限公司 | 利伐沙班中间体的制备方法和用途 | 
| JP7205529B2 (ja) * | 2018-02-26 | 2023-01-17 | 住友化学株式会社 | オキサゾリジノン化合物の製造方法 | 
| CN108546265A (zh) * | 2018-06-22 | 2018-09-18 | 苏州中联化学制药有限公司 | 一种利伐沙班中间体的合成方法 | 
| CN114105970A (zh) * | 2022-01-05 | 2022-03-01 | 安徽悦康凯悦制药有限公司 | 一种利伐沙班的制备方法 | 
| CN115754056B (zh) * | 2022-11-15 | 2025-04-08 | 乳源东阳光药业有限公司 | 一种检测5-氯噻吩-2-甲醛的方法 | 
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung | 
| DE10300111A1 (de) | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid | 
| DE10342570A1 (de) | 2003-09-15 | 2005-04-14 | Bayer Healthcare Ag | Verfahren zur Herstellung von 4-(4-Aminophenyl)-3-morpholinon | 
| DE102004002044A1 (de) | 2004-01-15 | 2005-08-04 | Bayer Healthcare Ag | Herstellverfahren | 
| US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof | 
| SI2459555T1 (sl) * | 2009-07-31 | 2022-03-31 | Krka, D.D., Novo Mesto | Postopek kristalizacije rivaroksabana | 
| WO2011080341A1 (en) | 2010-01-04 | 2011-07-07 | Enantia, S.L. | Process for the preparation of rivaroxaban and intermediates thereof | 
| EP2354128A1 (en) | 2010-02-10 | 2011-08-10 | Sandoz Ag | Method for the preparation of rivaroxaban | 
| EP2388260A1 (de) | 2010-05-21 | 2011-11-23 | Archimica GmbH | Herstellungsverfahren für einen Inhibitor eines Blutgerinnungsfaktors | 
| US20130253187A1 (en) | 2010-09-14 | 2013-09-26 | Medichem, S.A. | Process for Determining the Suitability for Distribution of a Batch of Thiophene-2-Carboxamide Derivative | 
| WO2012051692A1 (en) | 2010-10-18 | 2012-04-26 | Apotex Pharmachem Inc. | Processes for the preparation of rivaroxaban and intermediates thereof | 
| ES2395304B1 (es) | 2011-05-20 | 2014-01-16 | Interquim, S.A. | Procedimiento de obtención de una tiofen-2-carboxamida. | 
| CN102250076A (zh) * | 2011-05-27 | 2011-11-23 | 横店集团家园化工有限公司 | 一种利伐沙班中间体及利伐沙班的制备方法 | 
| CN102250077B (zh) * | 2011-06-15 | 2013-11-13 | 浙江工业大学 | 一种利伐沙班中间体及其用于合成利伐沙班的方法 | 
| EP2812329A2 (en) | 2012-02-06 | 2014-12-17 | Megafine Pharma (P) Ltd. | A process for preparation of rivaroxaban and intermediates thereof | 
- 
        2014
        - 2014-03-21 WO PCT/IB2014/060028 patent/WO2014155259A2/en not_active Ceased
- 2014-03-21 IN IN1113MU2013 patent/IN2013MU01113A/en unknown
- 2014-03-21 US US14/780,138 patent/US9663505B2/en not_active Expired - Fee Related
 
Also Published As
| Publication number | Publication date | 
|---|---|
| WO2014155259A2 (en) | 2014-10-02 | 
| US9663505B2 (en) | 2017-05-30 | 
| WO2014155259A3 (en) | 2015-01-29 | 
| US20160052919A1 (en) | 2016-02-25 |