IN2013DE03197A - - Google Patents
Info
- Publication number
- IN2013DE03197A IN2013DE03197A IN3197DE2013A IN2013DE03197A IN 2013DE03197 A IN2013DE03197 A IN 2013DE03197A IN 3197DE2013 A IN3197DE2013 A IN 3197DE2013A IN 2013DE03197 A IN2013DE03197 A IN 2013DE03197A
- Authority
- IN
- India
- Prior art keywords
- venlafaxine
- synthesis
- short
- isomer
- yield
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000003786 synthesis reaction Methods 0.000 abstract 3
- PNVNVHUZROJLTJ-MRXNPFEDSA-N 1-[(1s)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol Chemical compound C1=CC(OC)=CC=C1[C@@H](CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-MRXNPFEDSA-N 0.000 abstract 2
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 abstract 2
- 229960004688 venlafaxine Drugs 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/39—Preparation of carboxylic acid esters by oxidation of groups which are precursors for the acid moiety of the ester
- C07C67/42—Preparation of carboxylic acid esters by oxidation of groups which are precursors for the acid moiety of the ester by oxidation of secondary alcohols or ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3197DE2013 IN2013DE03197A (https=) | 2013-10-29 | 2014-10-29 | |
| PCT/IN2014/000687 WO2015063791A1 (en) | 2013-10-29 | 2014-10-29 | Novel process for total synthesis of venlafaxine |
| US15/033,506 US9527800B2 (en) | 2013-10-29 | 2014-10-29 | Process for total synthesis of venlafaxine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3197DE2013 IN2013DE03197A (https=) | 2013-10-29 | 2014-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013DE03197A true IN2013DE03197A (https=) | 2015-05-01 |
Family
ID=52144797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3197DE2013 IN2013DE03197A (https=) | 2013-10-29 | 2014-10-29 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9527800B2 (https=) |
| IN (1) | IN2013DE03197A (https=) |
| WO (1) | WO2015063791A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2013DE03197A (https=) | 2013-10-29 | 2015-05-01 | Council Scient Ind Res | |
| CN117700332A (zh) * | 2023-12-12 | 2024-03-15 | 上海佰利源医药科技有限公司 | 盐酸文拉法辛的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE56324B1 (en) * | 1982-12-13 | 1991-06-19 | American Home Prod | Phenethylamine derivatives and intermediates therefor |
| EP1249447B1 (en) | 2001-04-10 | 2008-10-22 | Alembic Limited | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol |
| US7612210B2 (en) | 2005-12-05 | 2009-11-03 | Wyeth | Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols |
| WO2010046808A2 (en) | 2008-10-21 | 2010-04-29 | Alembic Limited | A process for the preparation of venlafaxine hydrochloride |
| IN2013DE03197A (https=) | 2013-10-29 | 2015-05-01 | Council Scient Ind Res |
-
2014
- 2014-10-29 IN IN3197DE2013 patent/IN2013DE03197A/en unknown
- 2014-10-29 WO PCT/IN2014/000687 patent/WO2015063791A1/en not_active Ceased
- 2014-10-29 US US15/033,506 patent/US9527800B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20160272573A1 (en) | 2016-09-22 |
| US9527800B2 (en) | 2016-12-27 |
| WO2015063791A1 (en) | 2015-05-07 |
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