IN2012DN04868A - - Google Patents

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Publication number
IN2012DN04868A
IN2012DN04868A IN4868DEN2012A IN2012DN04868A IN 2012DN04868 A IN2012DN04868 A IN 2012DN04868A IN 4868DEN2012 A IN4868DEN2012 A IN 4868DEN2012A IN 2012DN04868 A IN2012DN04868 A IN 2012DN04868A
Authority
IN
India
Prior art keywords
compounds
compound
formula
methods
preparation
Prior art date
Application number
Other languages
English (en)
Inventor
Wei-Guo Su
Weihan Zhang
Hong Jia
Yumin Cui
Yongxin Ren
Yang Sai
Zhenping Wu
Wenji Li
Jiangyong Shao
Zhenping Tian
Original Assignee
Hutchison Medipharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44029398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN04868(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hutchison Medipharma Ltd filed Critical Hutchison Medipharma Ltd
Publication of IN2012DN04868A publication Critical patent/IN2012DN04868A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IN4868DEN2012 2009-11-23 2010-11-23 IN2012DN04868A (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2009101992592A CN102070618B (zh) 2009-11-23 2009-11-23 一种化合物及其晶体
PCT/CN2010/078997 WO2011060746A1 (en) 2009-11-23 2010-11-23 Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use

Publications (1)

Publication Number Publication Date
IN2012DN04868A true IN2012DN04868A (uk) 2015-09-25

Family

ID=44029398

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4868DEN2012 IN2012DN04868A (uk) 2009-11-23 2010-11-23

Country Status (18)

Country Link
US (2) US8658658B2 (uk)
EP (1) EP2504331B1 (uk)
JP (1) JP5758399B2 (uk)
KR (1) KR101513784B1 (uk)
CN (2) CN102070618B (uk)
AU (1) AU2010321366B2 (uk)
BR (1) BR112012012138B1 (uk)
CA (1) CA2781066C (uk)
DK (1) DK2504331T3 (uk)
ES (1) ES2529105T3 (uk)
IN (1) IN2012DN04868A (uk)
MX (1) MX2012005926A (uk)
MY (1) MY161749A (uk)
NZ (1) NZ600266A (uk)
PL (1) PL2504331T3 (uk)
PT (1) PT2504331E (uk)
RU (1) RU2507203C1 (uk)
WO (1) WO2011060746A1 (uk)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070618B (zh) 2009-11-23 2013-08-21 和记黄埔医药(上海)有限公司 一种化合物及其晶体
NZ728102A (en) * 2014-06-19 2018-04-27 Merial Inc Parasiticidal compositions comprising indole derivatives, methods and uses thereof
CN105985326B (zh) * 2015-02-16 2020-04-14 上海宣创生物科技有限公司 嘧啶衍生物晶型ⅲ及其制备方法和用途
WO2016187767A1 (en) * 2015-05-25 2016-12-01 Hutchison Medipharma Limited Pharmaceutical compositions and use thereof
JP7308145B2 (ja) * 2016-11-18 2023-07-13 ハッチソン メディファーマ リミテッド 固形腫瘍を治療するための医薬組成物
JP2020164434A (ja) * 2019-03-28 2020-10-08 上野製薬株式会社 2,6−ナフタレンビス(2−オキサゾリン)の製造方法
TW202143969A (zh) * 2020-03-09 2021-12-01 大陸商和記黃埔醫藥(上海)有限公司 抗pd-1抗體和多受體酪胺酸激酶抑制劑的藥物組合及其使用方法
US20240043409A1 (en) * 2021-04-12 2024-02-08 Mitoimmune Therapeutics Inc. Crystalline forms of 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-n-(tetrahydro-2h-pyran-4-yl)-1h-indol-7-amine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005095357A2 (en) * 2004-03-30 2005-10-13 Taisho Pharmaceutical Co., Ltd. Pyrimidine derivatives and methods of treatment related to the use thereof
EP1934200A1 (en) 2005-09-15 2008-06-25 Merck & Co., Inc. Tyrosine kinase inhibitors
EP2154967B9 (en) * 2007-04-16 2014-07-23 Hutchison Medipharma Enterprises Limited Pyrimidine derivatives
CN101289444B (zh) * 2007-04-16 2012-01-04 和记黄埔医药(上海)有限公司 一种嘧啶衍生物及其医药用途
TW201008933A (en) * 2008-08-29 2010-03-01 Hutchison Medipharma Entpr Ltd Pyrimidine compounds
CN102070618B (zh) * 2009-11-23 2013-08-21 和记黄埔医药(上海)有限公司 一种化合物及其晶体

Also Published As

Publication number Publication date
PL2504331T3 (pl) 2015-04-30
CA2781066A1 (en) 2011-05-26
CA2781066C (en) 2014-09-16
ES2529105T3 (es) 2015-02-16
US8658658B2 (en) 2014-02-25
JP2013511475A (ja) 2013-04-04
US8946249B2 (en) 2015-02-03
AU2010321366A8 (en) 2012-07-05
RU2012126112A (ru) 2013-12-27
PT2504331E (pt) 2015-02-20
KR101513784B1 (ko) 2015-04-20
DK2504331T3 (en) 2014-12-08
EP2504331B1 (en) 2014-11-12
JP5758399B2 (ja) 2015-08-05
RU2507203C1 (ru) 2014-02-20
WO2011060746A1 (en) 2011-05-26
BR112012012138B1 (pt) 2023-02-07
MY161749A (en) 2017-05-15
EP2504331A1 (en) 2012-10-03
CN102070618B (zh) 2013-08-21
AU2010321366A1 (en) 2012-06-14
BR112012012138A2 (pt) 2017-03-07
CN102648194A (zh) 2012-08-22
MX2012005926A (es) 2012-11-23
US20120270889A1 (en) 2012-10-25
CN102070618A (zh) 2011-05-25
KR20120097526A (ko) 2012-09-04
CN102648194B (zh) 2014-10-29
US20140200232A1 (en) 2014-07-17
EP2504331A4 (en) 2013-04-17
AU2010321366B2 (en) 2014-07-24
NZ600266A (en) 2014-06-27

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