IN2012DN04868A - - Google Patents

Download PDF

Info

Publication number
IN2012DN04868A
IN2012DN04868A IN4868DEN2012A IN2012DN04868A IN 2012DN04868 A IN2012DN04868 A IN 2012DN04868A IN 4868DEN2012 A IN4868DEN2012 A IN 4868DEN2012A IN 2012DN04868 A IN2012DN04868 A IN 2012DN04868A
Authority
IN
India
Prior art keywords
compounds
compound
formula
methods
preparation
Prior art date
Application number
Other languages
English (en)
Inventor
Wei-Guo Su
Weihan Zhang
Hong Jia
Yumin Cui
Yongxin Ren
Yang Sai
Zhenping Wu
Wenji Li
Jiangyong Shao
Zhenping Tian
Original Assignee
Hutchison Medipharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44029398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN04868(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hutchison Medipharma Ltd filed Critical Hutchison Medipharma Ltd
Publication of IN2012DN04868A publication Critical patent/IN2012DN04868A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IN4868DEN2012 2009-11-23 2010-11-23 IN2012DN04868A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2009101992592A CN102070618B (zh) 2009-11-23 2009-11-23 一种化合物及其晶体
PCT/CN2010/078997 WO2011060746A1 (en) 2009-11-23 2010-11-23 Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use

Publications (1)

Publication Number Publication Date
IN2012DN04868A true IN2012DN04868A (ja) 2015-09-25

Family

ID=44029398

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4868DEN2012 IN2012DN04868A (ja) 2009-11-23 2010-11-23

Country Status (18)

Country Link
US (2) US8658658B2 (ja)
EP (1) EP2504331B1 (ja)
JP (1) JP5758399B2 (ja)
KR (1) KR101513784B1 (ja)
CN (2) CN102070618B (ja)
AU (1) AU2010321366B2 (ja)
BR (1) BR112012012138B1 (ja)
CA (1) CA2781066C (ja)
DK (1) DK2504331T3 (ja)
ES (1) ES2529105T3 (ja)
IN (1) IN2012DN04868A (ja)
MX (1) MX2012005926A (ja)
MY (1) MY161749A (ja)
NZ (1) NZ600266A (ja)
PL (1) PL2504331T3 (ja)
PT (1) PT2504331E (ja)
RU (1) RU2507203C1 (ja)
WO (1) WO2011060746A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070618B (zh) * 2009-11-23 2013-08-21 和记黄埔医药(上海)有限公司 一种化合物及其晶体
PT3157912T (pt) 2014-06-19 2019-06-04 Boehringer Ingelheim Animal Health Usa Inc Composições parasiticidas compreendendo derivados de indole, seus métodos e suas utilizações
CN105985326B (zh) * 2015-02-16 2020-04-14 上海宣创生物科技有限公司 嘧啶衍生物晶型ⅲ及其制备方法和用途
WO2016187767A1 (en) * 2015-05-25 2016-12-01 Hutchison Medipharma Limited Pharmaceutical compositions and use thereof
US20190276439A1 (en) * 2016-11-18 2019-09-12 Hutchison Medipharma Limited Method of treating solid tumors
JP2020164434A (ja) * 2019-03-28 2020-10-08 上野製薬株式会社 2,6−ナフタレンビス(2−オキサゾリン)の製造方法
WO2021180027A1 (zh) * 2020-03-09 2021-09-16 和记黄埔医药(上海)有限公司 抗pd-1抗体和多受体酪氨酸激酶抑制剂的药物组合及其使用方法
JP2024515630A (ja) * 2021-04-12 2024-04-10 ミトイミューン・セラピューティクス・インコーポレイテッド 5-[(1,1-ジオキシド-4-チオモルホリニル)メチル]-2-フェニル-n-(テトラヒドロ-2h-ピラン-4-イル)-1h-インドール-7-アミンの新規結晶形

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ549673A (en) * 2004-03-30 2010-03-26 Taisho Pharmaceutical Co Ltd Pyrimidine derivatives and methods of treatment related to the use thereof
EP1934200A1 (en) 2005-09-15 2008-06-25 Merck & Co., Inc. Tyrosine kinase inhibitors
CN101289444B (zh) * 2007-04-16 2012-01-04 和记黄埔医药(上海)有限公司 一种嘧啶衍生物及其医药用途
DK2154967T5 (en) * 2007-04-16 2014-11-17 Hutchison Medipharma Entpr Ltd Pyriminderivater
TW201008933A (en) 2008-08-29 2010-03-01 Hutchison Medipharma Entpr Ltd Pyrimidine compounds
CN102070618B (zh) 2009-11-23 2013-08-21 和记黄埔医药(上海)有限公司 一种化合物及其晶体

Also Published As

Publication number Publication date
JP5758399B2 (ja) 2015-08-05
MX2012005926A (es) 2012-11-23
CN102070618B (zh) 2013-08-21
EP2504331A1 (en) 2012-10-03
AU2010321366A1 (en) 2012-06-14
BR112012012138B1 (pt) 2023-02-07
BR112012012138A2 (pt) 2017-03-07
CA2781066C (en) 2014-09-16
DK2504331T3 (en) 2014-12-08
CN102648194B (zh) 2014-10-29
EP2504331A4 (en) 2013-04-17
CA2781066A1 (en) 2011-05-26
ES2529105T3 (es) 2015-02-16
KR20120097526A (ko) 2012-09-04
JP2013511475A (ja) 2013-04-04
US8658658B2 (en) 2014-02-25
CN102648194A (zh) 2012-08-22
CN102070618A (zh) 2011-05-25
PT2504331E (pt) 2015-02-20
NZ600266A (en) 2014-06-27
US20120270889A1 (en) 2012-10-25
KR101513784B1 (ko) 2015-04-20
RU2012126112A (ru) 2013-12-27
RU2507203C1 (ru) 2014-02-20
WO2011060746A1 (en) 2011-05-26
AU2010321366A8 (en) 2012-07-05
EP2504331B1 (en) 2014-11-12
MY161749A (en) 2017-05-15
US8946249B2 (en) 2015-02-03
PL2504331T3 (pl) 2015-04-30
US20140200232A1 (en) 2014-07-17
AU2010321366B2 (en) 2014-07-24

Similar Documents

Publication Publication Date Title
MX2012001872A (es) Formulaciones intravenosas de antagonistas de neurocinina 1.
IN2012DN04868A (ja)
UA105229C2 (uk) Фармацевтичний склад
MY187718A (en) Pharmaceutical formulations
MY193277A (en) Certain amino-pyrimidines, compositions thereof, and methods for their use
MX2013003019A (es) Compuestos de azabenzotiazol, composiciones y metodos de uso.
TN2012000152A1 (en) Spiropiperidine compounds and pharmaceutical use thereof for treating diabetes
TN2012000248A1 (en) Novel spiropiperidine compounds
EP2590655A4 (en) COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
IN2012DN03182A (ja)
MX2011010415A (es) Formulaciones farmaceuticas que comprenden derivados de nitrocatecol y metodos para hacer las mismas.
WO2010128050A3 (en) Dihydroorotate - dehydrogenasee inhibitors as virostatic compounds
MX345780B (es) Inhibidores triciclicos de girasa.
WO2012015681A3 (en) Drug-ligand conjugates, synthesis thereof, and intermediates thereto
WO2012135615A3 (en) Enopeptins, uses thereof, and methods of synthesis thereto
MY160392A (en) Triptolide prodrugs
MX2013011926A (es) Derivados de glicosido y usos de los mismos.
TN2012000105A1 (en) Spirolactam derivatives and uses of same
WO2010123545A3 (en) Angiogenesis inhibitors
IN2012DN01292A (ja)
MX2013009386A (es) Nuevos compuestos de azaespirodecanona.
WO2012015687A3 (en) Drug-ligand conjugates, synthesis thereof, and intermediates thereto
WO2010146595A3 (en) Novel polymorphs of flibanserin hydrochloride
GEP20156269B (en) New secondary 8-hydroxyquinoline-7- carboxamide derivatives
WO2011125006A3 (en) Sultam compounds