IN2012DN02634A - - Google Patents
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- IN2012DN02634A IN2012DN02634A IN2634DEN2012A IN2012DN02634A IN 2012DN02634 A IN2012DN02634 A IN 2012DN02634A IN 2634DEN2012 A IN2634DEN2012 A IN 2634DEN2012A IN 2012DN02634 A IN2012DN02634 A IN 2012DN02634A
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- Prior art keywords
- binding proteins
- activity
- binding
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/545—IL-1
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25185609P | 2009-10-15 | 2009-10-15 | |
PCT/US2010/052849 WO2011047266A1 (en) | 2009-10-15 | 2010-10-15 | Il-1 binding proteins |
Publications (1)
Publication Number | Publication Date |
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IN2012DN02634A true IN2012DN02634A (es) | 2015-09-04 |
Family
ID=43876580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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IN2634DEN2012 IN2012DN02634A (es) | 2009-10-15 | 2010-10-15 |
Country Status (17)
Country | Link |
---|---|
US (2) | US8398966B2 (es) |
EP (1) | EP2488201A4 (es) |
JP (1) | JP2013507929A (es) |
KR (1) | KR20120104542A (es) |
CN (1) | CN102655880A (es) |
AR (1) | AR078650A1 (es) |
AU (1) | AU2010306681A1 (es) |
BR (1) | BR112012007365A2 (es) |
CA (1) | CA2775402A1 (es) |
IL (1) | IL219202A0 (es) |
IN (1) | IN2012DN02634A (es) |
MX (1) | MX2012004412A (es) |
RU (1) | RU2012119788A (es) |
TW (1) | TW201124427A (es) |
UY (1) | UY32949A (es) |
WO (1) | WO2011047266A1 (es) |
ZA (1) | ZA201202610B (es) |
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MY154067A (en) | 2008-05-30 | 2015-04-30 | Xbiotech Inc | IL-1a ABS AND METHODS OF USE |
TW201006485A (en) | 2008-06-03 | 2010-02-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
WO2009149189A2 (en) | 2008-06-03 | 2009-12-10 | Abbott Laboratories | Dual variable domain immunoglobulins and uses thereof |
JP5674654B2 (ja) * | 2008-07-08 | 2015-02-25 | アッヴィ・インコーポレイテッド | プロスタグランジンe2二重可変ドメイン免疫グロブリンおよびその使用 |
AU2010289527C1 (en) * | 2009-09-01 | 2014-10-30 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
EP2488658A4 (en) * | 2009-10-15 | 2013-06-19 | Abbvie Inc | IMMUNOGLOBULINE WITH DOUBLE VARIABLE DOMAIN AND ITS USE |
UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
ES2684475T3 (es) * | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
CN107596365A (zh) | 2010-06-18 | 2018-01-19 | 埃克斯生物科技公司 | 关节炎治疗 |
BR112013002578A2 (pt) | 2010-08-03 | 2019-05-14 | Abbvie Inc. | imunoglobinas de domínio variável duplo e usos das mesmas |
KR101910760B1 (ko) | 2010-08-23 | 2018-10-22 | 엑스바이오테크, 인크. | 종양성 질병들에 대한 치료 |
TW201211252A (en) | 2010-08-26 | 2012-03-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
MY163368A (en) | 2010-12-21 | 2017-09-15 | Abbvie Inc | Il-1-alpha and -beta bispecific dual variable domain immunoglobulins and their use |
CN103596591B (zh) | 2011-02-08 | 2016-08-24 | Abbvie公司 | 骨关节炎和疼痛的治疗 |
US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
EP2726504A1 (en) * | 2011-05-27 | 2014-05-07 | Dutalys | Antibodies with improved folding stability |
RU2622021C2 (ru) | 2011-09-23 | 2017-06-08 | ИксБиотеч, Инк. | Лечение кахексии |
WO2013102042A2 (en) | 2011-12-30 | 2013-07-04 | Abbvie Inc. | Dual specific binding proteins directed against il-13 and/or il-17 |
DK2814843T3 (da) | 2012-02-13 | 2020-06-22 | Agency Science Tech & Res | IL-ß-NEUTRALISERENDE HUMANE MONOKLONALE ANTISTOFFER |
WO2014011955A2 (en) | 2012-07-12 | 2014-01-16 | Abbvie, Inc. | Il-1 binding proteins |
CN103588878A (zh) * | 2012-08-15 | 2014-02-19 | 江苏泰康生物医药有限公司 | 一种人源化抗人白细胞介素1 β单克隆抗体及其制备与应用 |
WO2014035361A1 (en) * | 2012-08-26 | 2014-03-06 | R-PHARM, CJSC (Closed Joint Stock Company) | IL-1β INHIBITOR COMPOSITION AND USE THEREOF |
US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
RU2017137740A (ru) | 2012-11-01 | 2019-02-11 | Эббви Инк. | Анти-vegf/dll4-иммуноглобулины с двойными вариабельными доменами и их применения |
EP2919811B1 (en) * | 2012-11-16 | 2018-12-26 | Novartis AG | Use of il-1beta binding antibodies for treating peripheral arterial disease |
US9550986B2 (en) | 2012-12-21 | 2017-01-24 | Abbvie Inc. | High-throughput antibody humanization |
EP2970459A2 (en) | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Dual specific binding proteins directed against il-1beta and il-17 |
US20160367520A1 (en) | 2014-02-10 | 2016-12-22 | Patara Pharma, LLC | Mast cell stabilizers for lung disease treatment |
SI3104853T1 (sl) | 2014-02-10 | 2020-03-31 | Respivant Sciences Gmbh | Zdravljenje s stabilizatorji mastocitov za sistemske motnje |
TW201623331A (zh) * | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法 |
WO2015168474A1 (en) | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Fusion proteins for treating cancer and related methods |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
US20160168640A1 (en) | 2014-11-10 | 2016-06-16 | Genentech, Inc. | Therapeutic and diagnostic methods for il-33-mediated disorders |
CA2963719A1 (en) * | 2014-11-10 | 2016-05-19 | F. Hoffmann-La Roche Ag | Anti-il-1beta antibodies and methods of use |
EP3218399A1 (en) | 2014-11-10 | 2017-09-20 | F. Hoffmann-La Roche AG | Bispecific antibodies and methods of use in ophthalmology |
EA201791029A1 (ru) | 2014-11-10 | 2017-12-29 | Дженентек, Инк. | Антитела против интерлейкина-33 и их применение |
WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
US20180291097A1 (en) * | 2015-06-04 | 2018-10-11 | Craig Basson | Use of il-1 beta binding antibodies to treat peripheral arterial disease |
TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
EP3331522A1 (en) | 2015-08-07 | 2018-06-13 | Patara Pharma LLC | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
US10265296B2 (en) | 2015-08-07 | 2019-04-23 | Respivant Sciences Gmbh | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
AU2017321495A1 (en) | 2016-08-31 | 2019-03-21 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
JP2019531308A (ja) | 2016-10-07 | 2019-10-31 | レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh | 肺線維症の治療のためのクロモリン組成物 |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
CA3046387A1 (en) * | 2016-12-21 | 2018-06-28 | David Jose Simon LAINE | Antibodies that specifically bind to human il-15 and uses thereof |
CA3053231A1 (en) | 2017-02-16 | 2018-08-23 | Xbiotech Inc. | Treatment of hidradenitis suppurativa |
JP2020533353A (ja) * | 2017-09-13 | 2020-11-19 | ノバルティス アーゲー | アルコール性肝炎の治療のためのil−1b結合抗体の使用 |
CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
US11434291B2 (en) | 2019-05-14 | 2022-09-06 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
KR102087743B1 (ko) * | 2019-06-10 | 2020-03-12 | 을지대학교 산학협력단 | IL-1beta에 특이적으로 결합하는 항체 및 그의 용도 |
KR20220152262A (ko) | 2020-03-13 | 2022-11-15 | 제넨테크, 인크. | 항-인터루킨-33 항체 및 이의 용도 |
US12006366B2 (en) | 2020-06-11 | 2024-06-11 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
EP4198055A1 (en) * | 2020-08-13 | 2023-06-21 | Sunshine Lake Pharma Co., Ltd. | Antibody of il-11 and use thereof |
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WO1995001997A1 (en) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
IL153567A0 (en) * | 2000-06-29 | 2003-07-06 | Abbott Lab | Dual specificity antibodies and methods of making and using |
US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
US20050070692A1 (en) * | 2002-02-28 | 2005-03-31 | Beals John Michael | Anti-interleukin-1 beta analogs |
EP1590369B1 (en) * | 2003-01-24 | 2016-03-16 | Applied Molecular Evolution, Inc. | Human il-1 beta antagonists |
GB0303337D0 (en) * | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
AU2004280333A1 (en) * | 2003-08-22 | 2005-04-21 | Medimmune, Llc | Humanization of antibodies |
SI1899378T1 (sl) * | 2005-06-21 | 2010-02-26 | Xoma Technology Ltd | IL-1Beta vezavna protitelesa in njihovi fragmenti |
US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
US20090215992A1 (en) * | 2005-08-19 | 2009-08-27 | Chengbin Wu | Dual variable domain immunoglobulin and uses thereof |
JP2009513645A (ja) * | 2005-10-26 | 2009-04-02 | ノバルティス アクチエンゲゼルシャフト | IL−1β化合物の新規使用 |
PL2097455T3 (pl) | 2006-11-02 | 2015-04-30 | Genentech Inc | Humanizowane przeciwciała przeciw czynnikowi D |
CA2710252C (en) * | 2007-12-20 | 2017-03-28 | Xoma Technology Ltd. | Methods for the treatment of gout |
PE20120586A1 (es) * | 2009-01-29 | 2012-06-17 | Abbott Lab | Proteinas de union a il-1 |
US20110016506A1 (en) * | 2009-07-15 | 2011-01-20 | Yung-Yu Lu | Set-Top Box |
TWI522365B (zh) * | 2010-05-14 | 2016-02-21 | 艾伯維有限公司 | Il-1結合蛋白 |
-
2010
- 2010-10-15 JP JP2012534395A patent/JP2013507929A/ja not_active Withdrawn
- 2010-10-15 IN IN2634DEN2012 patent/IN2012DN02634A/en unknown
- 2010-10-15 MX MX2012004412A patent/MX2012004412A/es not_active Application Discontinuation
- 2010-10-15 WO PCT/US2010/052849 patent/WO2011047266A1/en active Application Filing
- 2010-10-15 CN CN2010800563660A patent/CN102655880A/zh active Pending
- 2010-10-15 US US12/905,499 patent/US8398966B2/en active Active
- 2010-10-15 EP EP10824167.0A patent/EP2488201A4/en not_active Withdrawn
- 2010-10-15 CA CA2775402A patent/CA2775402A1/en not_active Abandoned
- 2010-10-15 TW TW099135501A patent/TW201124427A/zh unknown
- 2010-10-15 RU RU2012119788/10A patent/RU2012119788A/ru not_active Application Discontinuation
- 2010-10-15 BR BR112012007365A patent/BR112012007365A2/pt not_active IP Right Cessation
- 2010-10-15 KR KR1020127012405A patent/KR20120104542A/ko not_active Application Discontinuation
- 2010-10-15 UY UY0001032949A patent/UY32949A/es not_active Application Discontinuation
- 2010-10-15 AU AU2010306681A patent/AU2010306681A1/en not_active Abandoned
- 2010-10-15 AR ARP100103772A patent/AR078650A1/es unknown
-
2012
- 2012-04-11 ZA ZA2012/02610A patent/ZA201202610B/en unknown
- 2012-04-15 IL IL219202A patent/IL219202A0/en unknown
-
2013
- 2013-02-25 US US13/775,540 patent/US20130295004A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2013507929A (ja) | 2013-03-07 |
ZA201202610B (en) | 2012-12-27 |
KR20120104542A (ko) | 2012-09-21 |
CN102655880A (zh) | 2012-09-05 |
US20130295004A1 (en) | 2013-11-07 |
CA2775402A1 (en) | 2011-04-21 |
IL219202A0 (en) | 2012-06-28 |
AU2010306681A1 (en) | 2012-04-19 |
TW201124427A (en) | 2011-07-16 |
RU2012119788A (ru) | 2013-11-20 |
MX2012004412A (es) | 2012-05-08 |
US20110142761A1 (en) | 2011-06-16 |
US8398966B2 (en) | 2013-03-19 |
AR078650A1 (es) | 2011-11-23 |
EP2488201A4 (en) | 2013-12-25 |
EP2488201A1 (en) | 2012-08-22 |
UY32949A (es) | 2011-02-28 |
BR112012007365A2 (pt) | 2016-11-22 |
WO2011047266A1 (en) | 2011-04-21 |
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