IN2012DN02576A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02576A
IN2012DN02576A IN2576DEN2012A IN2012DN02576A IN 2012DN02576 A IN2012DN02576 A IN 2012DN02576A IN 2576DEN2012 A IN2576DEN2012 A IN 2576DEN2012A IN 2012DN02576 A IN2012DN02576 A IN 2012DN02576A
Authority
IN
India
Prior art keywords
oxaliplatin
nanoparticle
mixed
supercritical fluid
mixture solution
Prior art date
Application number
Other languages
English (en)
Inventor
Sung Jae Lee
Young Hoon Kim
Sang Heon Lee
Kab Sig Kim
Original Assignee
Jw Pharmaceutical Corportion
Bio Synectics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jw Pharmaceutical Corportion, Bio Synectics Inc filed Critical Jw Pharmaceutical Corportion
Publication of IN2012DN02576A publication Critical patent/IN2012DN02576A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN2576DEN2012 2009-09-21 2010-09-20 IN2012DN02576A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20090089079 2009-09-21
PCT/KR2010/006459 WO2011034394A2 (fr) 2009-09-21 2010-09-20 Nanoparticules d'oxaliplatine et leur procédé de préparation

Publications (1)

Publication Number Publication Date
IN2012DN02576A true IN2012DN02576A (fr) 2015-08-28

Family

ID=43759199

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2576DEN2012 IN2012DN02576A (fr) 2009-09-21 2010-09-20

Country Status (11)

Country Link
US (1) US9393201B2 (fr)
EP (1) EP2481396A4 (fr)
JP (1) JP5759464B2 (fr)
KR (1) KR101396461B1 (fr)
CN (1) CN102665689B (fr)
AU (1) AU2010296180B2 (fr)
CA (1) CA2774669C (fr)
IN (1) IN2012DN02576A (fr)
MX (1) MX348668B (fr)
RU (1) RU2563997C2 (fr)
WO (1) WO2011034394A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015022234A2 (pt) * 2013-03-15 2017-07-18 Dsm Ip Assets Bv nanopartículas de lípidos sólidos (ii)
CA3022777A1 (fr) * 2017-04-21 2018-10-25 Bio-Synectics Inc. Procede de preparation de nanoparticules de materiau actif a l'aide de lipide en tant que lubrifiant en vue de broyage
KR101895237B1 (ko) * 2017-06-12 2018-09-07 목포대학교산학협력단 옥살리플라틴을 포함하는 경구용 약물전달 조성물 및 이의 제조방법
KR102184117B1 (ko) * 2017-10-31 2020-11-30 주식회사 삼양바이오팜 수용해도 및 생체이용율이 개선된 소라페닙 나노입자 경구용 조성물 및 이의 제조 방법
CA3111861C (fr) 2018-09-14 2023-11-07 Inserm (Institut National De La Sante Et De La Recherche Medicale) Systeme d'administration de medicaments a base de platine
CN113730570A (zh) * 2019-09-26 2021-12-03 苏州百迈生物医药有限公司 一种化疗免疫组合药物及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0774963B1 (fr) * 1994-08-08 2000-11-02 Debiopharm S.A. Preparation pharmaceutiquement stable d'oxaliplatine
FR2740686B1 (fr) 1995-11-03 1998-01-16 Sanofi Sa Formulation pharmaceutique lyophilisee stable
CN1191067C (zh) 1997-02-05 2005-03-02 法玛西雅厄普约翰美国公司 高不溶性铂配合物的脂质复合物和脂质体
GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations
CA2369263A1 (fr) * 1999-04-09 2000-10-19 Jessie Au Methodes et compositions ameliorant la diffusion d'agents therapeutiques a l'interieur de tissus
US7217735B1 (en) * 1999-04-09 2007-05-15 Au Jessie L-S Methods and compositions for enhancing delivery of therapeutic agents to tissues
US7012072B2 (en) 2000-12-12 2006-03-14 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
CN101022790A (zh) * 2003-08-28 2007-08-22 梅恩医药有限公司 含有酸的奥沙利铂制剂
KR100603974B1 (ko) * 2003-12-05 2006-07-25 김갑식 고체상 지질을 용매로 이용한 나노수준의 또는 비결정질입자의 제조 방법
CN1775216A (zh) * 2004-11-15 2006-05-24 胡才忠 一种新型的制剂——奥沙利铂脂质体
DE102005011786A1 (de) * 2005-03-11 2006-09-14 Pharmasol Gmbh Verfahren zur Herstellung ultrafeiner Submicron-Suspensionen
BRPI0617663A2 (pt) * 2005-10-21 2011-08-02 Panacea Biotec Ltd composições aperfeiçoadas para terapia de cáncer
KR20070067768A (ko) 2005-12-23 2007-06-29 주식회사 삼양사 안정한 옥살리플라틴 조성물 및 이의 제조방법
GR20060100144A (el) * 2006-03-03 2007-10-17 Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene
JP4830019B2 (ja) * 2006-05-04 2011-12-07 バイオ−シネクティクス インク. ナノスケールの活物質粒子の製造方法
KR101342119B1 (ko) * 2006-05-04 2013-12-18 (주)바이오시네틱스 디올 화합물을 이용한 나노수준의 활성물질 입자 제조 방법
CN1868455A (zh) * 2006-05-20 2006-11-29 沈阳药科大学 奥沙利铂磷脂复合物静脉给药的纳米混悬注射剂
KR100913063B1 (ko) 2006-09-13 2009-08-21 주식회사유한양행 옥살리플라틴-함유 주사용 용액
WO2008086756A1 (fr) * 2007-01-12 2008-07-24 Yanfang Li Matériaux emboliques de vaisseau sanguin, microsphériques, biodégradables et développables
CN100563646C (zh) * 2007-07-13 2009-12-02 陈祥峰 一种奥沙利铂脂质体葡萄糖制剂的制备方法
JP2010533714A (ja) * 2007-07-16 2010-10-28 ポニアード ファーマシューティカルズ, インコーポレイテッド ピコプラチンのための経口製剤

Also Published As

Publication number Publication date
JP5759464B2 (ja) 2015-08-05
US20120177728A1 (en) 2012-07-12
JP2013505291A (ja) 2013-02-14
WO2011034394A3 (fr) 2011-11-03
CA2774669C (fr) 2017-12-19
AU2010296180B2 (en) 2016-05-05
AU2010296180A1 (en) 2012-04-19
RU2012116085A (ru) 2013-10-27
CN102665689B (zh) 2015-04-22
US9393201B2 (en) 2016-07-19
MX2012003393A (es) 2012-07-25
EP2481396A2 (fr) 2012-08-01
RU2563997C2 (ru) 2015-09-27
KR101396461B1 (ko) 2014-05-20
KR20120046243A (ko) 2012-05-09
EP2481396A4 (fr) 2014-03-05
CA2774669A1 (fr) 2011-03-24
MX348668B (es) 2017-06-23
CN102665689A (zh) 2012-09-12
WO2011034394A2 (fr) 2011-03-24

Similar Documents

Publication Publication Date Title
IN2012DN02576A (fr)
MX2011006771A (es) Metodo de preparacion de una composicion de micelas polimericas que contienen un farmaco pobremente soluble en agua.
MY160460A (en) Agomelatine hydrochloride hydrate and preparation thereof
WO2013093648A3 (fr) Procédé de fabrication de nanoparticules lipidiques pour une administration de médicament
MY154015A (en) A hydrogen halide complex of agomelatine and preparation thereof
WO2007005633A8 (fr) Procede de preparation d'une forme posologique liquide contenant du 4-phenylbutyrate de sodium
MY194905A (en) Processes and Intermediates for Preparing a Medicament
MY167395A (en) Method for producing glufosinate p free acid
AR079580A1 (es) Procesos para la fabricacion de un agente farmaceuticamente activo
CN104586758B (zh) 一种对乙酰氨基酚注射液及其制备方法
WO2010045281A3 (fr) Formulations aqueuses stables de medicaments insolubles ou peu solubles dans l'eau
GB2505859A8 (en) Aripiprazole type I microcrystal, aripiprazole solid preparation, and preparation method
MX2013012206A (es) Metodo para producir substancias con gas sobresaturado,dispositivo de suministro transdermico de las mismas, y usos de las mismas.
MX2020010290A (es) Composiciones anestesicas de liberacion sostenida y metodos de preparacion de las mismas.
WO2011063774A3 (fr) Complexes stéroïdes à base de pectine et compositions pharmaceutiques réalisées à partir de ces complexes
MX2020001760A (es) Composicion farmaceutica que incluye un comprimido esferoide de multiples unidades que contiene esomeprazol y una sal farmaceuticamente aceptable esferoide de este, y metodo para preparar la composicion farmaceutica.
CN103126986A (zh) 一种丁酸氯维地平静脉注射用乳剂及其制备方法
WO2012145554A3 (fr) Procédé de production de substances comprenant un gaz sursaturé, dispositif d'administration transdermique de ces substances, et utilisations de celles-ci
CN104086611B (zh) 灯盏花甲素衍生物及其制备方法与用途
CN103751104A (zh) 依达拉奉注射液及其制备方法
WO2012145555A3 (fr) Procédé de production de substances comprenant un gaz sursaturé, dispositif d'administration transdermique de ces substances, et utilisations de celles-ci
CN102166185A (zh) 等渗纳洛酮注射液及其制备方法
CN102100668B (zh) 高级脂肪酸衍生物微乳及其制备方法和应用
CN102406605A (zh) 雄性激素类药物的醇质体制剂及其制备方法
CN101716169A (zh) 一种多西他赛药物组合物及其制备方法