IN2012DN02423A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02423A
IN2012DN02423A IN2423DEN2012A IN2012DN02423A IN 2012DN02423 A IN2012DN02423 A IN 2012DN02423A IN 2423DEN2012 A IN2423DEN2012 A IN 2423DEN2012A IN 2012DN02423 A IN2012DN02423 A IN 2012DN02423A
Authority
IN
India
Prior art keywords
mif
cxcr2
cxcr4
homomultimer
inhibits
Prior art date
Application number
Other languages
English (en)
Inventor
Jurgen Bernhagen
Christian Weber
Benedikt Vollrath
Court Turner
Joshua Robert Schultz
Alma Zernecke
Sergio Duron
Original Assignee
Carolus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carolus Therapeutics Inc filed Critical Carolus Therapeutics Inc
Publication of IN2012DN02423A publication Critical patent/IN2012DN02423A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IN2423DEN2012 2009-09-23 2010-09-23 IN2012DN02423A (OSRAM)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24521409P 2009-09-23 2009-09-23
US31903910P 2010-03-30 2010-03-30
PCT/US2010/050047 WO2011038149A2 (en) 2009-09-23 2010-09-23 Methods of treating inflammation

Publications (1)

Publication Number Publication Date
IN2012DN02423A true IN2012DN02423A (OSRAM) 2015-08-21

Family

ID=43796491

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2423DEN2012 IN2012DN02423A (OSRAM) 2009-09-23 2010-09-23

Country Status (9)

Country Link
EP (1) EP2480579A4 (OSRAM)
KR (1) KR20120105429A (OSRAM)
CN (1) CN102725311A (OSRAM)
AU (1) AU2010298249A1 (OSRAM)
BR (1) BR112012006468A2 (OSRAM)
CA (1) CA2773978A1 (OSRAM)
IN (1) IN2012DN02423A (OSRAM)
MX (1) MX2012003514A (OSRAM)
WO (1) WO2011038149A2 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2731970B1 (en) 2011-07-15 2018-11-28 MorphoSys AG Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
US9328174B2 (en) 2012-05-09 2016-05-03 Novartis Ag Chemokine receptor binding polypeptides
NZ702315A (en) * 2012-05-17 2016-10-28 Cyon Therapeutics Inc Methods and uses for pro protein convertase subtilisin kexin 9 (pcsk9) inhibitors
TW201605886A (zh) * 2013-11-14 2016-02-16 巴克斯特保健公司 作爲治療標靶的mif
CN113893252A (zh) 2016-03-11 2022-01-07 阿迪亚生命科学公司 用于治疗结晶性关节病症的cxcr-2抑制剂
MX2020013155A (es) 2018-06-05 2021-04-29 Anji Pharma Us Llc Composiciones y metodos para tratar la pancreatitis.
AU2019417313B2 (en) * 2018-12-26 2023-01-19 Colgate-Palmolive Company Biomarkers of neutrophil deregulation as diagnostic for gingivitis
KR20220166809A (ko) * 2020-03-11 2022-12-19 바이오라인알엑스 리미티드 급성 호흡곤란 증후군 및 바이러스 감염 치료를 위한 cxcr4 억제제
US20210338626A1 (en) * 2020-04-28 2021-11-04 Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch Methods for treating or preventing a viral infection or inhibiting viral replication
CN112656934A (zh) * 2021-01-22 2021-04-16 深圳市图微安创科技开发有限公司 多肽at03在治疗原发性胆汁性胆管炎药物中的应用
EP4378319A1 (en) * 2022-12-01 2024-06-05 Bioiberica, S.A.U. Composition comprising bioactive peptides
CN119318647A (zh) * 2024-08-14 2025-01-17 南方医科大学 Sb225002在制备治疗心肌梗死的药物中的应用、治疗心肌梗死的组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
WO2003072753A2 (en) * 2002-02-27 2003-09-04 Emory University Multimeric binding complexes
EP1483294B2 (en) * 2002-03-01 2019-10-30 Immunomedics, Inc. Internalizing anti-cd74 antibodies and methods of use
WO2005065328A2 (en) * 2003-12-30 2005-07-21 The United States Of America, As Represented By The Department Of Veterans Affairs Macrophage migration inhibitory factor (mif) as marker for urological inflammatory disease
US7612181B2 (en) * 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
KR20110014141A (ko) * 2008-03-20 2011-02-10 카롤러스 테라퓨틱스, 인코포레이티드 염증을 치료하는 방법
WO2010056910A2 (en) * 2008-11-12 2010-05-20 Carolus Therapeutics, Inc. Methods of treating cardiovascular disorders

Also Published As

Publication number Publication date
MX2012003514A (es) 2012-04-19
CA2773978A1 (en) 2011-03-31
CN102725311A (zh) 2012-10-10
BR112012006468A2 (pt) 2016-08-09
WO2011038149A3 (en) 2011-10-27
AU2010298249A1 (en) 2012-04-19
EP2480579A2 (en) 2012-08-01
EP2480579A4 (en) 2013-07-31
KR20120105429A (ko) 2012-09-25
WO2011038149A2 (en) 2011-03-31

Similar Documents

Publication Publication Date Title
IN2012DN02423A (OSRAM)
WO2009117710A3 (en) Methods of treating inflammation
MX2010006823A (es) Metodos para el tratamiento de la gota.
AU2008232453A8 (en) Methods and compositions for reduction of side effects of therapeutic treatments
MX2010009724A (es) Procedimientos de tratamiento del dolor inflamatorio-.
MX2018013333A (es) Composiciones de nucleasas terapeuticas y metodos.
MY191313A (en) Use of chimeric antigen receptor-modified t cells to treat cancer
MX2011007930A (es) Conjugados de insulina cristalina.
PH12014500075A1 (en) Pharmaceutical composition, methods for treating and uses thereof
TW200738262A (en) Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
WO2009080800A3 (en) Method for decreasing abdominal girth by administering a bifidobacterium bacteria
MX2011006725A (es) Combinacion de inhibidores de aurora cinasa y anticuerpos anti-cd20.
WO2011044523A3 (en) Compositions and methods for treating obesity
SG179069A1 (en) Cancer stem cell-targeted and drug resistant cancer therapy
EP2566502A4 (en) METHODS OF TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND PROVIDING CARDIOVASCULAR PROTECTION
MX2011012538A (es) Terapia de combinacion para el tratamiento del mieloma multiple.
AU2010298020A8 (en) Combination
WO2008073317A3 (en) Cytarabine for treatment of glioma
TN2011000206A1 (en) Compositions and methods of use soluble thrombomodulin variants
PH12012500873A1 (en) Multilayer pharmaceutical composition that can be dispersed in water and which contains a combination of antimalarial agents
UA41936U (ru) Способ лечения крауроза вульвы в детском возрасте
UA83743C2 (ru) Способ профилактики и коррекции сниженных функциональных возможностей центральной нервной системы
UA54014U (ru) Способ лечения больных хроническим некалькулезным холециститом в сочетании с ожирением
TN2010000463A1 (en) Compositions and methods for preparing and using same
UA27829U (en) Method for treating prosthetic stomatitis against the background of metabolic syndrome